1. Peptides
  2. DOTATATE

DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

DOTATATE Chemical Structure

DOTATATE Chemical Structure

CAS No. : 177943-88-3

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1 mg USD 80 In-stock
5 mg USD 250 In-stock
10 mg USD 420 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of DOTATATE:

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  • Biological Activity

  • Purity & Documentation

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Description

DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT)[1][2][3][4].

In Vivo

177Lu-DOTATATE shows excellent antitumor effects in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

1435.62

Formula

C65H90N14O19S2

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

{DOTA}-{d-Phe}-CY-{d-Trp}-KTCT (Disulfide bridge:Cys2-Cys7)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (69.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6966 mL 3.4828 mL 6.9656 mL
5 mM 0.1393 mL 0.6966 mL 1.3931 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6966 mL 3.4828 mL 6.9656 mL 17.4141 mL
5 mM 0.1393 mL 0.6966 mL 1.3931 mL 3.4828 mL
10 mM 0.0697 mL 0.3483 mL 0.6966 mL 1.7414 mL
15 mM 0.0464 mL 0.2322 mL 0.4644 mL 1.1609 mL
20 mM 0.0348 mL 0.1741 mL 0.3483 mL 0.8707 mL
25 mM 0.0279 mL 0.1393 mL 0.2786 mL 0.6966 mL
30 mM 0.0232 mL 0.1161 mL 0.2322 mL 0.5805 mL
40 mM 0.0174 mL 0.0871 mL 0.1741 mL 0.4354 mL
50 mM 0.0139 mL 0.0697 mL 0.1393 mL 0.3483 mL
60 mM 0.0116 mL 0.0580 mL 0.1161 mL 0.2902 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DOTATATE
Cat. No.:
HY-106244
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