2. Others Antibody-drug Conjugate/ADC Related Neuronal Signaling GPCR/G Protein Apoptosis
  3. Drug Derivative Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor Apoptosis
  4. NOTA-Octreotide

NOTA‑Octreotide is a selective SSTR2‑targeting PET tracer. NOTA‑Octreotide binds specifically to SSTR2 and accumulates in SSTR2‑expressing tissues. NOTA‑Octreotide enables effective imaging of somatostatin receptor‑positive tumors in mice and shows high specific uptake in SSTR2‑expressing organs in healthy rats. NOTA-Octreotide can be used for PET imaging investigation of neuroendocrine tumors..

For research use only. We do not sell to patients.

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NOTA-Octreotide

NOTA-Octreotide Chemical Structure

CAS No. : 1427427-01-7

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NOTA-Octreotide Related Antibodies

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SSTR1 SSTR2 SSTR3 SSTR5 SSTR4

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Description

NOTA‑Octreotide is a selective SSTR2‑targeting PET tracer. NOTA‑Octreotide binds specifically to SSTR2 and accumulates in SSTR2‑expressing tissues. NOTA‑Octreotide enables effective imaging of somatostatin receptor‑positive tumors in mice and shows high specific uptake in SSTR2‑expressing organs in healthy rats. NOTA-Octreotide can be used for PET imaging investigation of neuroendocrine tumors.[1].

Molecular Weight

1304.54

Formula

C61H85N13O15S2
CAS No.
Sequence

NOTA-{d-Phe}-Cys-Phe-{d-Trp}-Lys-Thr-Cys-{Threoninol} (Disulfide bridge: Cys2-Cys7)
Sequence Shortening

NOTA-{d-Phe}-CF{d-Trp}-KTC-{Threoninol} (Disulfide bridge: Cys2-Cys7)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NOTA-Octreotide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOTA-Octreotide1427427-01-7Drug DerivativeRadionuclide-Drug Conjugates (RDCs)Somatostatin ReceptorApoptosisDrug derivativeSSTRsSSTRhealthy ratsSSTR2-expressing tissuesPETpositron emission tomographySSTR2somatostatin receptor 2neuroendocrine tumorsHPLCSSTR2-positive tumor miceInhibitorinhibitorinhibit

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