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Cat. No.: HY-P3902

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[D-Trp8] Somatostatin-14

[D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin.

For research use only. We do not sell to patients.

CAS No.: 58976-46-8
Formula: C₇₆H₁₀₄N₁₈O₁₉S₂
Molecular Weight:1637.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

[D-Trp8] Somatostatin-14 Chemical Structure

CAS No.: 58976-46-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

[D-Trp8] Somatostatin-14, a tetradecapeptide, is an analog of Somatostatin more potent than the native Somatostatin^[1].

All Somatostatin Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	2.3 nM Compound: 2, [DTrp8]-SRIF	Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography Displacement of 125I-[LTT]-SRIF-28 from human sst1 receptor in CHO cells after 2 hrs by autoradiography	[PMID: 21806016]
HEK293	IC₅₀	3.1 nM Compound: 2, [DTrp8]-SRIF	Displacement of 125I-[LTT]-SRIF-28 from human sst5 receptor in HEK293 cells after 2 hrs by autoradiography Displacement of 125I-[LTT]-SRIF-28 from human sst5 receptor in HEK293 cells after 2 hrs by autoradiography	[PMID: 21806016]

In Vitro

[D-Trp8] Somatostatin-14 is 6-8 times more potent than Somatostatin to inhibit the release of growth hormone, glucagon and Insulin^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 58976-46-8
Molecular Weight 1637.88
Formula C₇₆H₁₀₄N₁₈O₁₉S₂
Sequence Shortening

AGCKNFF-{D-Trp}-KTFTSC (disulfide bridge:Cys3-Cys14)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J Rivier, et al. D-Trp8-somatostatin: an analog of somatostatin more potent than the native molecule. Biochem Biophys Res Commun. 1975 Jul 22;65(2):746-51. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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[D-Trp8] Somatostatin-14

All Somatostatin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

[D-Trp8] Somatostatin-14 Related Classifications

HY-P3902 Related Classifications