JKC 301
JKC 301 is a selective Endothelin A receptor antagonist. JKC 301 attenuates the pressor effects of nicotine in rats. JKC 301 can be used to study cardiovascular disease caused by smoking.
For research use only. We do not sell to patients.
- CAS No.: 136553-96-3
- Formula: C32H44N6O7
- Molecular Weight:624.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Vasopressin Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 136553-96-3
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Molecular Weight 624.73
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Formula C32H44N6O7
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Sequence
Cyclo({d-Asp}-Pro-{d-Ile}-Leu-{d-Trp})
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Sequence Shortening
Cyclo({d-Asp}-P-{d-Ile}-L-{d-Trp})
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tanus-Santos JE, Sampaio RC, Hyslop S, Franchini KG, Moreno H Jr. Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. Eur J Pharmacol. 2000 May 12;396(1):33-7. [Content Brief]
[2]. Ngoka LC, et al. Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions. J Mass Spectrom. 2000 Feb;35(2):265-76. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)