(D-Trp6)-LHRH free acid

Name: (D-Trp6)-LHRH free acid
Brand: MedChemExpress
SKU: HY-P4572
Rating: 4.5 (1 reviews)

Cat. No.: HY-P4572 Pureza: 99.67%: Ficha de datos
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(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist.

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Síntesis de péptidos personalizados

(D-Trp6)-LHRH free acid Estructura química

No. CAS : 129418-54-8

Tamaño	Stock	Cantidad
1 mg	En stock	Estimated Time of Arrival: December 31
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto
100 mg	Obtener un presupuesto

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Revisión del cliente

Based on 1 publication(s) in Google Scholar

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•Related Small Molecules:

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Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

(D-Trp6)-LHRH free acid is a luteinizing hormone-releasing hormone (LHRH) agonist^[1].

In Vitro

(D-Trp6)-LHRH (10 μM; 24 h or 6 days) free acid reduces the proliferation of human epithelial ovarian cancer cell lines EFO-21 and EFO-27^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

1312.43

Fòrmula

C₆₄H₈₁N₁₇O₁₄

No. CAS

129418-54-8

Appearance

Solid

Color

White to off-white

Sequence

{Pyr}-His-Trp-Ser-Tyr-{d-Trp}-Leu-Arg-Pro-Gly

Sequence Shortening

{Pyr}-HWSY-{d-Trp}-LRPG

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture and light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvente y solubilidad

In Vitro:

DMSO : 100 mg/mL (76.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.7619 mL	3.8097 mL	7.6195 mL
5 mM	0.1524 mL	0.7619 mL	1.5239 mL
10 mM	0.0762 mL	0.3810 mL	0.7619 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.67%

Select Batch:

Ficha de datos (275 KB) SDS (419 KB)

COA (253 KB) RP-HPLC (266 KB) MS (69 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Emons G, et al. High affinity binding and direct antiproliferative effects of LHRH analogues in human ovarian cancer cell lines. Cancer Res. 1993 Nov 15;53(22):5439-46. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	0.7619 mL	3.8097 mL	7.6195 mL	19.0486 mL
	5 mM	0.1524 mL	0.7619 mL	1.5239 mL	3.8097 mL
	10 mM	0.0762 mL	0.3810 mL	0.7619 mL	1.9049 mL
	15 mM	0.0508 mL	0.2540 mL	0.5080 mL	1.2699 mL
	20 mM	0.0381 mL	0.1905 mL	0.3810 mL	0.9524 mL
	25 mM	0.0305 mL	0.1524 mL	0.3048 mL	0.7619 mL
	30 mM	0.0254 mL	0.1270 mL	0.2540 mL	0.6350 mL
	40 mM	0.0190 mL	0.0952 mL	0.1905 mL	0.4762 mL
	50 mM	0.0152 mL	0.0762 mL	0.1524 mL	0.3810 mL
	60 mM	0.0127 mL	0.0635 mL	0.1270 mL	0.3175 mL