1. GPCR/G Protein
    Neuronal Signaling
  2. Somatostatin Receptor
  3. BIM-23190

BIM-23190 

Cat. No.: HY-P3124
Handling Instructions

BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

BIM-23190 Chemical Structure

BIM-23190 Chemical Structure

CAS No. : 182153-96-4

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Description

BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly[1][3].

In Vitro

BIM-23190 tends to mildly stimulate PRL secretion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

BIM-23190 (50 μg/mouse, twice a day) exhibits significant anti-tumor (C6 glioma) activity[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male athymic nude (nu/nu) mice, 5-6 wk old (C6 glioma)[2].
Dosage: 50 μg/mouse
Administration: Injected twice a day for 19 days.
Result: Significantly reduced the tumor growth rate.
Molecular Weight

1202.45

Formula

C₅₇H₇₉N₁₃O₁₂S₂

CAS No.

182153-96-4

Sequence

{4-(2-Hydroxyethyl)-1-piperazinylacetyl}-{D-Phe}-Cys-Tyr-{D-Trp}-Lys-{Abu}-Cys-Thr-NH2 (Disulfide bridge: Cys2-Cys7)

Sequence Shortening

{4-(2-Hydroxyethyl)-1-piperazinylacetyl}-{D-Phe}-CY-{D-Trp}-K-{Abu}-CT-NH2 (Disulfide bridge: Cys2-Cys7)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

BIM-23190BIM23190BIM 23190Somatostatin ReceptorSSTRsSSTRanti-tumorgliomaInhibitorinhibitorinhibit

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BIM-23190
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HY-P3124
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