77 Results for "

adenosine derivative

" in MedChemExpress (MCE) Product Catalog:
Products (77)

77 Results for "adenosine derivative" in MCE Product Catalog:

30
30 Publications Verification
Cat. No.: HY-B1511
CAS No.: 60-92-4
Synonyms: Cyclic adenosine monophosphate; adenosine cyclic 3', 5'-monophosphate; cAMP
Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
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30
30 Publications Verification
Cat. No.: HY-B1511A
CAS No.: 37839-81-9
Synonyms: Cyclic adenosine monophosphate sodium; adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium
Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .
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20
20 Cited Publications
Cat. No.: HY-19528
CAS No.: 979-92-0
Synonyms: SAH (S-Adenosylhomocysteine)
SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM .
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15
15 Cited Publications
Cat. No.: HY-N0262
CAS No.: 73-03-0
Synonyms: 3'-Deoxyadenosine
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .
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9
9 Cited Publications
Cat. No.: HY-100937
CAS No.: 102146-07-6
Purity:  99.96%
Synonyms: PD 116948
Target:  

Adenosine Receptor

Research Areas:  

Cardiovascular Disease

DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective Adenosine A1 receptor antagonist, with a Ki of 0.46 nM in 3H-CHA binding to A1 receptors in rat whole brain membranes .
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4
4 Cited Publications
Cat. No.: HY-N6631
CAS No.: 1621-56-3
Target:  

AMPK

Research Areas:  

Metabolic Disease Cancer

7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
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1
1 Cited Publications
Cat. No.: HY-B0128
CAS No.: 479-18-5
Synonyms: Diprophylline
Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema .
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1
1 Cited Publications
Cat. No.: HY-B1505
CAS No.: 652-37-9
Synonyms: Theophyllineacetic acid; Theophylline-7-acetic acid
Acefylline (Theophyllineacetic acid), a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .
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1
1 Cited Publications
Cat. No.: HY-114986
CAS No.: 67786-53-2
Purity:  ≥99.0%
Synonyms: 6-keto-Prostaglandin E1
Target:  

β-glucuronidase

Research Areas:  

Cardiovascular Disease

6-Keto-PGE1 (6-keto-Prostaglandin E1) is a biologically active derivative of PGE1. 6-Keto-PGE1 inhibits adenosine diphosphate-induced platelet aggregation. 6-Keto-PGE1 reduces cardiac afterload, decreases the accumulation of plasma myocardial depressant factor (MDF), lowers arterial blood pressure, dilates vascular beds, inhibits the vasoconstrictive response of vascular smooth muscle, and increases pulmonary compliance. 6-Keto-PGE1 directly stabilizes isolated cat liver lysosomes and significantly reduces the release of β-glucuronidase and cathepsin D. 6-Keto-PGE1 prolongs the survival time of traumatized rats and exerts protective effects through hemodynamic and cytoprotective actions. 6-Keto-PGE1 reduces central airway resistance. 6-Keto-PGE1 can be used in studies related to traumatic shock .
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Cat. No.: HY-W017163
CAS No.: 552-62-5
7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity .
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Cat. No.: HY-W016009
CAS No.: 653-63-4
2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
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Cat. No.: HY-103322
CAS No.: 1135306-29-4
Target:  

PKA Potassium Channel

Research Areas:  

Metabolic Disease Cancer

6-Bnz-cAMP sodium, a derivative of cyclic adenosine monophosphate (cAMP), is a selective PKA activator with inhibitory activity against the bTREK-1 K + channel. 6-Bnz-cAMP sodium does not activate the Epac signaling pathway. It inhibits the bTREK-1 K + channel via a voltage-independent, ATP-dependent mechanism that is independent of the PKA/Epac/calmodulin kinase/MAP kinase pathway. 6-Bnz-cAMP sodium activates CREB phosphorylation to regulate osteoblast-specific gene expression, induces osteoblast differentiation, promotes extracellular matrix mineralization, supports osteoblast proliferation, and shows no cytotoxicity toward osteoblasts. It can be used in studies related to bone tissue repair and regeneration .
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Cat. No.: HY-W402064
CAS No.: 16265-37-5
Research Areas:  

Others

N-Acetyladenosine is an adenosine analog and an adenosine N 6-acylated derivative. N-Acetyladenosine can be produced via the heterolytic reaction between adenosine and diacetyl peroxide .
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Cat. No.: HY-W048491
CAS No.: 168427-74-5
Research Areas:  

Others

2′-O-(2-Methoxyethyl)adenosine is an ATP (HY-B2176) derivative. 2′-O-(2-Methoxyethyl)adenosine can be used for oligonucleotide synthesis .
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Cat. No.: HY-W250153
CAS No.: 109434-21-1
Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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Cat. No.: HY-119413
CAS No.: 2715-68-6
Purity:  99.87%
9-Ethyladenine is a precursor of competitive antagonists of adenosine receptors (A1, A2, A3), with no significant inhibitory effect on adenine phosphoribosyltransferase (APRT). 9-Ethyladenine derivatives have high affinity and selectivity for A1 (Ki=27 nM), A2A (Ki=46 nM), and A3 (Ki=86 nM) receptors. 9-Ethyladenine does not inhibit brain APRT activity, can be used in the study of adenosine receptor-related diseases (such as nervous system diseases) models .
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Cat. No.: HY-19528S
Synonyms: SAH (S-Adenosylhomocysteine)-d4
SAH-d4 is the deuterium labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM .
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Cat. No.: HY-B1511R
CAS No.: 60-92-4
Synonyms: Cyclic adenosine monophosphate (Standard); adenosine cyclic 3', 5'-monophosphate (Standard); cAMP (Standard)
Research Areas:  

Cancer

Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
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Cat. No.: HY-164090
CAS No.: 482-67-7
Target:  

P2Y Receptor

Research Areas:  

Cardiovascular Disease

Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
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Cat. No.: HY-W105272
CAS No.: 2922-74-9
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
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