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adenosine derivative

" in MedChemExpress (MCE) Product Catalog:

78

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5

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11

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1511
    Cyclic AMP
    Maximum Cited Publications
    25 Publications Verification

    Cyclic adenosine monophosphate; adenosine cyclic 3', 5'-monophosphate; cAMP

    		 Endogenous Metabolite Neurological Disease Metabolic Disease Cancer
    Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
    Cyclic AMP
  • HY-19528
    SAH
    15+ Cited Publications

    SAH (S-Adenosylhomocysteine)

    		 Endogenous Metabolite Metabolic Disease
    SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 µM .
    SAH
  • HY-N0262
    Cordycepin
    10+ Cited Publications

    3'-Deoxyadenosine

    		 TNF Receptor MMP Bacterial Autophagy Antibiotic Infection Inflammation/Immunology Cancer
    Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .
    Cordycepin
  • HY-B1511A
    Cyclic AMP sodium
    20+ Cited Publications

    Cyclic adenosine monophosphate sodium; adenosine cyclic 3', 5'-monophosphate sodium; cAMP sodium

    		 Biochemical Assay Reagents Neurological Disease Metabolic Disease Cancer
    Cyclic AMP (Cyclic adenosine monophosphate) sodium, adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP sodium is an important second messenger in many biological processes .
    Cyclic AMP sodium
  • HY-100937
    DPCPX
    5+ Cited Publications

    PD 116948

    		 Adenosine Receptor Cardiovascular Disease
    DPCPX (PD 116948), a xanthine derivative, is a highly potent and selective Adenosine A1 receptor antagonist, with a Ki of 0.46 nM in 3H-CHA binding to A1 receptors in rat whole brain membranes .
    DPCPX
  • HY-B0128
    Diphylline
    1 Publications Verification

    Diprophylline

    		 Adenosine Receptor Phosphodiesterase (PDE) Cardiovascular Disease Inflammation/Immunology
    Diphylline (Diprophylline) is a potent A1/A2 adenosine receptor antagonist and cyclic nucleotide phosphodiesterase inhibitor. Diphylline, a xanthine derivative, is a bronchodilator and vasodilator agent and has the potential for chronic bronchitis and emphysema .
    Diphylline
  • HY-W017163
    7-Methylxanthine

    		Endogenous Metabolite Adenosine Receptor Metabolic Disease
    7-Methylxanthine is an orally active methyl derivative of xanthine and a non-selective adenosine receptor antagonist. 7-Methylxanthine is also one of the purine components of human urinary calculi. 7-Methylxanthine has anti-myopia activity .
    7-Methylxanthine
  • HY-W016009
    2'-Deoxyadenosine-5'-monophosphate

    		Endogenous Metabolite Metabolic Disease
    2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2'-Deoxyadenosine-5'-monophosphate
  • HY-B1505
    Acefylline
    1 Publications Verification

    Theophyllineacetic acid; Theophylline-7-acetic acid

    		 Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE) Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Acefylline (Theophyllineacetic acid), a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .
    Acefylline
  • HY-103322
    6-Bnz-cAMP sodium salt

    		PKA Potassium Channel Metabolic Disease Cancer
    6-Bnz-cAMP sodium, a derivative of cyclic adenosine monophosphate (cAMP), is a selective PKA activator with inhibitory activity against the bTREK-1 K + channel. 6-Bnz-cAMP sodium does not activate the Epac signaling pathway. It inhibits the bTREK-1 K + channel via a voltage-independent, ATP-dependent mechanism that is independent of the PKA/Epac/calmodulin kinase/MAP kinase pathway. 6-Bnz-cAMP sodium activates CREB phosphorylation to regulate osteoblast-specific gene expression, induces osteoblast differentiation, promotes extracellular matrix mineralization, supports osteoblast proliferation, and shows no cytotoxicity toward osteoblasts. It can be used in studies related to bone tissue repair and regeneration .
    6-Bnz-cAMP sodium salt
  • HY-W402064
    N-Acetyladenosine

    		Nucleoside Antimetabolite/Analog Others
    N-Acetyladenosine is an adenosine analog and an adenosine N 6-acylated derivative. N-Acetyladenosine can be produced via the heterolytic reaction between adenosine and diacetyl peroxide .
    N-Acetyladenosine
  • HY-W048491
    2′-O-(2-Methoxyethyl)adenosine

    		DNA/RNA Synthesis Drug Derivative Others
    2′-O-(2-Methoxyethyl)adenosine is an ATP (HY-B2176) derivative. 2′-O-(2-Methoxyethyl)adenosine can be used for oligonucleotide synthesis .
    2′-O-(2-Methoxyethyl)adenosine
  • HY-W250153
    Adenosine 3'-phosphate 5'-phosphosulfate lithium

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate lithium, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
    Adenosine 3'-phosphate 5'-phosphosulfate lithium
  • HY-119413
    9-Ethyladenine

    		Adenosine Receptor Neurological Disease
    9-Ethyladenine is a precursor of competitive antagonists of adenosine receptors (A1, A2, A3), with no significant inhibitory effect on adenine phosphoribosyltransferase (APRT). 9-Ethyladenine derivatives have high affinity and selectivity for A1 (Ki=27 nM), A2A (Ki=46 nM), and A3 (Ki=86 nM) receptors. 9-Ethyladenine does not inhibit brain APRT activity, can be used in the study of adenosine receptor-related diseases (such as nervous system diseases) models .
    9-Ethyladenine
  • HY-19528S
    SAH-d4

    SAH (S-Adenosylhomocysteine)-d4

    		 Endogenous Metabolite Metabolic Disease
    SAH-d4 is the deuterium labeled SAH. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM .
    SAH-d4
  • HY-B1511R
    Cyclic AMP (Standard)

    Cyclic adenosine monophosphate (Standard); adenosine cyclic 3', 5'-monophosphate (Standard); cAMP (Standard)

    		 Endogenous Metabolite Reference Standards Cancer
    Cyclic AMP (Standard) is the analytical standard of Cyclic AMP. Cyclic AMP (Cyclic adenosine monophosphate), adenosine triphosphate derivative, is an intracellular signaling molecule responsible for directing cellular responses to extracellular signals. Cyclic AMP is an important second messenger in many biological processes .
    Cyclic AMP (Standard)
  • HY-N6631
    7-Methoxyisoflavone
    4 Publications Verification

    		 AMPK Metabolic Disease Cancer
    7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK).
    7-Methoxyisoflavone
  • HY-164090
    Adenosine 3'-phosphate 5'-phosphosulfate

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
    Adenosine 3'-phosphate 5'-phosphosulfate
  • HY-W105272
    2′-Deoxyadenosine 5′-monophosphate disodium

    		Endogenous Metabolite Metabolic Disease
    2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2′-Deoxyadenosine 5′-monophosphate disodium
  • HY-W010744
    DMT-dI

    5'-O-DMT-dI; 2'-Deoxy-5'-O-DMT-inosine

    		 Phosphoramidites Nucleoside Antimetabolite/Analog Cancer
    DMT-dI (5'-O-DMT-dI) is a deoxyribonucleoside containing a hypoxanthine base. DMT-dI can be used to prepare convertible nucleoside derivatives to prepare modified oligonucleotides complementary to target genes for gene editing. DMT-dI can be used to study various conditions, disorders or diseases modified by adenosine .
    DMT-dI
  • HY-101854
    N6-(2-Phenylethyl)adenosine

    N6-Phenethyladenosine; N6-Phenylethyladenosine

    		 Adenosine Receptor Inflammation/Immunology Cancer
    N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potent adenosine receptors (AR) agonist with Ki values of 11.8 nM, 30.1 nM, 0.63 nM for rat A1AR, human A1AR and hA3AR, respectively .
    N6-(2-Phenylethyl)adenosine
  • HY-111809
    N6-Ethyladenosine

    		Adenosine Receptor Others
    N6-Ethyladenosine is an adenosine derivative, acts as a Adenosine receptor agonist, with Kis of 4.9 and 4.7 nM for hA1AR and hA3AR, respectively .
    N6-Ethyladenosine
  • HY-W178327
    8-Chloro caffeine

    		Adenosine Receptor Cancer
    8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine .
    8-Chloro caffeine
  • HY-19528R
    SAH (Standard)

    SAH (S-Adenosylhomocysteine) (Standard)

    		 Reference Standards Endogenous Metabolite Metabolic Disease
    SAH (Standard) is the analytical standard of SAH. This product is intended for research and analytical applications. SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM .
    SAH (Standard)
  • HY-N0262R
    Cordycepin (Standard)

    3'-Deoxyadenosine (Standard)

    		 TNF Receptor Reference Standards MMP Bacterial Autophagy Antibiotic Infection Inflammation/Immunology Cancer
    Cordycepin (Standard) is the analytical standard of Cordycepin. This product is intended for research and analytical applications. Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner . Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase .
    Cordycepin (Standard)
  • HY-107203
    Propentofylline

    HWA 285

    		 Phosphodiesterase (PDE) Neurological Disease Inflammation/Immunology
    Propentofylline is a xanthine-derivative that inhibits adenosine uptake and blocks phosphodiesterase activity. Propentofylline has neuroprotective, antiproliferative, and anti-inflammatory effects that improve cognition and dementia severity in patients with Alzheimer's disease or vascular dementia.
    Propentofylline
  • HY-B1505A
    Acefylline piperazine

    Theophyllineacetic acid piperazine; Theophylline-7-acetic acid piperazine

    		 Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE) Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Acefylline (Theophyllineacetic acid) piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research .
    Acefylline piperazine
  • HY-D2361
    Adenosine 2'-PEG-Biotin

    		Nucleoside Antimetabolite/Analog Others
    Adenosine 2'-PEG-Biotin is a biochemical reagent derived from adenosine. Adenosine 2'-PEG-Biotin regulates cell signaling pathways by mimicking the effects of endogenous adenosine and binding to its receptors. Adenosine 2'-PEG-Biotin can be used in the research of bioprobes, biosensors and diagnostic reagents .
    Adenosine 2'-PEG-Biotin
  • HY-W016009R
    2'-Deoxyadenosine-5'-monophosphate (Standard)

    		Reference Standards Endogenous Metabolite Metabolic Disease
    2'-Deoxyadenosine-5'-monophosphate (Standard) is the analytical standard of 2'-Deoxyadenosine-5'-monophosphate. This product is intended for research and analytical applications. 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2'-Deoxyadenosine-5'-monophosphate (Standard)
  • HY-147908
    Adenosine receptor inhibitor 2

    		Xanthine Oxidase Adenosine Receptor Inflammation/Immunology
    Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor. Adenosine receptor inhibitor 2 shows dual affinity toward A1/A2A ARs with higher affinity for the A1- than the A2AAR. Adenosine receptor inhibitor 2 has Ki values of 52.2 nM for the A1AR and 167 nM for the A2AAR .
    Adenosine receptor inhibitor 2
  • HY-146332
    Collagen-IN-1

    		P-selectin Cardiovascular Disease
    Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .
    Collagen-IN-1
  • HY-162082
    METTL1-WDR4-IN-2

    		DNA Methyltransferase Cancer
    METTL1-WDR4-IN-2, an adenosine derivative, is a selective methyltransferase Like 1 (METTL1)-WDR4 inhibitor with an IC50 of 41 μM. METTL1-WDR4-IN-2 shows selectivity against METTL3-14 (IC50 of 958 μM) and METTL16 (IC50 of 208 μM). METTL1-WDR4-IN-2 can be used for the study of cancer .
    METTL1-WDR4-IN-2
  • HY-152656
    2-Hydrazinyl-adenosine

    		Drug Intermediate Adenosine Receptor Neurological Disease
    2-Hydrazinyl-adenosine is a synthetic intermediate. Derivatives of 2-Hydrazinyl-adenosine act as A2A adenosine receptor agonists. 2-Hydrazinyl-adenosine is used in the research of neurodegenerative diseases .
    2-Hydrazinyl-adenosine
  • HY-21601
    5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine

    		Phosphoramidites Nucleoside Antimetabolite/Analog Others
    5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
    5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
  • HY-N9422
    Adenosine 3'-phosphate 5'-phosphosulfate triethylamine

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate triethylamine, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate triethylamine can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
    Adenosine 3'-phosphate 5'-phosphosulfate triethylamine
  • HY-13631ES2
    Deruxtecan-d4-1

    MC-GGFG-DXD-d4-1

    		 Drug-Linker Conjugates for ADC Isotope-Labeled Compounds Others
    Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
    Deruxtecan-d4-1
  • HY-W016009S
    2'-Deoxyadenosine-5'-monophosphate-d12 dilithium

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    2'-Deoxyadenosine-5'-monophosphate-d12 dilithium is deuterium labeled 2'-Deoxyadenosine-5'-monophosphate (HY-W016009). 2′-Deoxyadenosine 5′-monophosphate, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate can be used to study adenosine-based interactions during DNA synthesis and DNA damage.
    2'-Deoxyadenosine-5'-monophosphate-d12 dilithium
  • HY-W105272S
    2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 disodium

    		Endogenous Metabolite Metabolic Disease
    2′-Deoxyadenosine 5′-monophosphate- 13C10, 15N5 (disodium) is the 13C and 15N labeled 2′-Deoxyadenosine 5′-monophosphate disodium . 2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide found in DNA. 2′-Deoxyadenosine 5′-monophosphate disodium can be used to study adenosine-based interactions during DNA synthesis and DNA damage .
    2′-Deoxyadenosine 5′-monophosphate-13C10,15N5 disodium
  • HY-N1717
    2-Acetylbenzoic acid

    		Platelet-activating Factor Receptor (PAFR) Cardiovascular Disease
    2-Acetylbenzoic acid, a Benzoic acid (HY-N0216) derivative, is a weak platelet aggregation inhibitor. 2-Acetylbenzoic acid inhibits Adenosine 5'-diphosphate (ADP, HY-W010918)-induced platelet aggregation .
    2-Acetylbenzoic acid
  • HY-W250153A
    Adenosine 3'-phosphate 5'-phosphosulfate lithium, hydrate

    		P2Y Receptor Cardiovascular Disease
    Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate, an adenine nucleotide derivative, is a selective P2Y1 antagonist with no effect on P2Y2, P2Y4, or P2Y6 receptors. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can competitive inhibit ADP-induced platelet aggregation, as well as the ability of ADP to cause shape change and increases in Ca 2+ in platelets, but had no effect on the inhibition of stimulated adenylate cyclase by ADP. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate is a co-substrate used for the sulfonation of glycans. Adenosine 3'-phosphate 5'-phosphosulfate lithium hydrate can be used for Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays, which as donor substrate to transfer a sulfonate group .
    Adenosine 3'-phosphate 5'-phosphosulfate lithium, hydrate
  • HY-19528S2
    SAH-13C10

    		Endogenous Metabolite Metabolic Disease
    SAH- 13C10 is the 13C labeled SAH . SAH (S-Adenosylhomocysteine) is an amino acid derivative and a modulartor in several metabolic pathways. It is an intermediate in the synthesis of cysteine and adenosine . SAH is an inhibitor for METTL3-METTL14 heterodimer complex (METTL3-14) with an IC50 of 0.9 μM .
    SAH-13C10
  • HY-131831A
    6-Bn-ADP sodium

    N6-benzyl ADP sodium

    		 ATP Synthase Cancer
    6-Bn-ADP (N6-benzyl ADP) sodium is a derivative of Adenosine 5'-diphosphate (ADP) (HY-W010918) that inhibits ATP hydrolysis. 6-Bn-ADP sodium inhibits the ATPase activities of Mortalin, Hsc70, and Hsp70 protein with Kis of 86.51 μM, 294.5 μM, and 1612 μM, respectively .
    6-Bn-ADP sodium
  • HY-B1505R
    Acefylline (Standard)

    Theophyllineacetic acid (Standard); Theophylline-7-acetic acid (Standard)

    		 Reference Standards Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE) Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Acefylline (Theophyllineacetic acid) (Standard) is the analytical standard of Acefylline (HY-B1505). This product is intended for research and analytical applications. Acefylline (Theophyllineacetic acid), a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline can be used in asthma research .
    Acefylline (Standard)
  • HY-103168
    XCC

    		Adenosine Receptor Neurological Disease
    XCC, 1,3,8-substituted xanthine derivative, is an adenosine receptor antagonist with Ki of 1.905 μM[1].
    XCC
  • HY-N7517
    Adenosine 5′-monophosphoramidate sodium

    		Nucleoside Antimetabolite/Analog Others
    Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP .
    Adenosine 5′-monophosphoramidate sodium
  • HY-173579
    2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate trisodium

    2'(3')-AEC-ADP trisodium

    		 Nucleoside Antimetabolite/Analog Others
    2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate (2'(3')-AEC-ADP) trisodium is a derivative of Adenosine 5'-diphosphate (ADP) (HY-W010918).
    2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate trisodium
  • HY-117715
    CK-3197

    		Phosphodiesterase (PDE) Cardiovascular Disease
    CK-3197 is a weak inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase (CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure .
    CK-3197
  • HY-134246
    7-CH-5'-dAMP

    5'-dTuMP

    		 Nucleoside Antimetabolite/Analog Others
    7-CH-5'-dAMP (5'-dTuMP) is an adenylate derivative that acts as a potential substrate, competitive inhibitor, or modulator of enzymes that interact with 2-deoxyadenosine-5-monophosphate .
    7-CH-5'-dAMP
  • HY-134372A
    Bis-Br-ANT-ATP tetrasodium

    		Adenylate Cyclase Bacterial Infection
    Bis-Br-ANT-ATP (tetrasodium) is a fluorescent derivative of adenosine-5’-triphosphate (ATP) (HY-B2176). Bis-Br-ANT-ATP (tetrasodium) selectively inhibits B. pertussis adenylyl cyclase toxin CyaA (Ki: 12.6 nM). Bis-Br-ANT-ATP (tetrasodium) can be used in Whooping cough research .
    Bis-Br-ANT-ATP tetrasodium
  • HY-134283
    8-Benzylthio-cAMP

    		PKA Apoptosis Others
    8-Benzylthio-cAMP is a derivative of cyclic adenosine monophosphate (cAMP). 8-Bn-cAMP is a site-selective activator of cAMP-dependent protein kinases. Compared with cyclic adenosine monophosphate, it is more stable to phosphodiesterase (PDE) hydrolysis and has higher membrane permeability. 8-Bn-cAMP can be used to study the role of cAMP in regulating cell proliferation, differentiation and apoptosis .
    8-Benzylthio-cAMP

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