1. GPCR/G Protein
  2. Adenosine Receptor
  3. N6-(2-Phenylethyl)adenosine

N6-(2-Phenylethyl)adenosine (Synonyms: N6-Phenethyladenosine; N6-Phenylethyladenosine)

Cat. No.: HY-101854 Purity: 99.86%
Handling Instructions

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potent adenosine receptors (AR) agonist with Ki values of 11.8 nM, 30.1 nM, 0.63 nM for rat A1AR, human A1AR and hA3AR, respectively.

For research use only. We do not sell to patients.

N6-(2-Phenylethyl)adenosine Chemical Structure

N6-(2-Phenylethyl)adenosine Chemical Structure

CAS No. : 20125-39-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
50 mg USD 228 In-stock
Estimated Time of Arrival: December 31
100 mg USD 396 In-stock
Estimated Time of Arrival: December 31
200 mg USD 708 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine), an adenosine derivative, is a potent adenosine receptors (AR) agonist with Ki values of 11.8 nM, 30.1 nM, 0.63 nM for rat A1AR, human A1AR and hA3AR, respectively[1].

IC50 & Target

Ki: 11.8 nM (rA1AR), 30.1 nM (hA1AR) and 0.63 nM (hA3AR)[1]

In Vitro

N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) inhibits rA2AR (IC50=560 nM), hA2AR (IC50=2250 nM) in CHO cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

371.39

Formula

C₁₈H₂₁N₅O₄

CAS No.

20125-39-7

SMILES

OC[[email protected]@H]1[[email protected]]([[email protected]]([[email protected]](N2C=NC3=C2N=CN=C3NCCC4=CC=CC=C4)O1)O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (269.26 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6926 mL 13.4629 mL 26.9259 mL
5 mM 0.5385 mL 2.6926 mL 5.3852 mL
10 mM 0.2693 mL 1.3463 mL 2.6926 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.73 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.86%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

N6-(2-Phenylethyl)adenosineN6-Phenethyladenosine N6-PhenylethyladenosineAdenosine ReceptorP1 receptoradenosinederivativeARA1ARA2ARA3ARInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
N6-(2-Phenylethyl)adenosine
Cat. No.:
HY-101854
Quantity:
MCE Japan Authorized Agent: