Acefylline (Theophyllineacetic acid) (GMP), a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline (GMP) is a peptidylarginine deiminase (PAD) activator. Acefylline (GMP) is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline (GMP) can be used in asthma research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 652-37-9
- Formule: C9H10N4O4
- Masse moléculaire:238.20
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
-
HY-B1505
AcefyllineAdenosine Receptor Antagonist -
HY-B1505R
Acefylline (Standard)Analytical Standard -
HY-19533
SCH 58261A2A Receptor Antagonist -
HY-19532
ZM241385A2A Receptor Antagonist -
HY-100937
DPCPXA1 Receptor Antagonist -
HY-103173
5'-N-EthylcarboxamidoadenosineAdenosine Receptor Agonist -
HY-Y1055
GuanineGuanine Nucleotide -
HY-10888
IstradefyllineAdenosine A2A Receptor Antagonist -
HY-B0809
TheophyllinePDE Inhibitor -
HY-B0715
PentoxifyllinePDE Inhibitor -
HY-A0168
RegadenosonVasodilator/A2A Adenosine Receptor Agonist -
HY-17422
AcyclovirHSV Inhibitor
Voir tous les produits spécifiques à Isoform Adenosine Receptor
More
Activité biologique
Description
In Vitro
Acefylline (GMP) (200 μM; 5-180 min) is an effective PDA activator[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 652-37-9
-
Masse moléculaire 238.20
-
Formule C9H10N4O4
-
SMILES
O=C(O)CN1C=NC(N(C)C(N2C)=O)=C1C2=O
-
Synonyms
Theophyllineacetic acid (GMP); Theophylline-7-acetic acid (GMP)
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Ferretti C, et al. Inhibitory effect of theophylline, theophylline-7-acetic acid, ambroxol and ambroxol-theophylline-7-acetate on rat lung cAMP phosphodiesterase isoenzymes. Int J Tissue React. 1992;14(1):31-6. [Content Brief]
[2]. Méchin MC, et, al. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. J Dermatol Sci. 2016 Feb;81(2):101-6. [Content Brief]
[3]. Tsvetkova B, Tencheva J, Peikov P. Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether. Acta Pharm. 2006 Jun;56(2):251-7. PMID: 16613730. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Acefylline (GMP) Related Classifications
HY-B1505G Related Classifications
Powered by Bioz