2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. Adenosine 5′-monophosphoramidate sodium

Adenosine 5′-monophosphoramidate sodium 

Cat. No.: HY-N7517 Purity: ≥96.0%
COA Handling Instructions

Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP.

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Adenosine 5′-monophosphoramidate sodium Chemical Structure

Adenosine 5′-monophosphoramidate sodium Chemical Structure

CAS No. : 102029-68-5

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Description

Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis. Adenosine 5′-monophosphoramidate has a significant effect on the accumulation of cyclic AMP[1].
Molecular Weight

368.22

Appearance

Solid

Formula

C10H14N6NaO6P
CAS No.
SMILES

O[[email protected]]([[email protected]@H]1O)[[email protected]](O[[email protected]@H]1CO[P](N)(O[Na])=O)([H])N2C3=NC=NC(N)=C3N=C2
Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro: 

DMSO : ≥ 25 mg/mL (67.89 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7158 mL 13.5788 mL 27.1577 mL
5 mM 0.5432 mL 2.7158 mL 5.4315 mL
10 mM 0.2716 mL 1.3579 mL 2.7158 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.79 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.79 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.79 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥96.0%

COA (255 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Adenosine 5′-monophosphoramidate102029-68-5Nucleoside Antimetabolite/AnalognucleotideNH2pAadenosine,derivative,cyclic AMPintermediatenucleotide synthesisInhibitorinhibitorinhibit

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Adenosine 5′-monophosphoramidate sodium
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