2'-NH2-ATP
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling.
For research use only. We do not sell to patients.
- CAS No.: 61468-88-0
- Formula: C10H17N6O12P3
- Molecular Weight:506.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2'-NH2-ATP (2 mM) did not replace ATP as a substrate for NH3-dependent cytidine 5'-triphosphate (CTP) formation catalyzed by CTP synthase[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 61468-88-0
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Molecular Weight 506.20
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Formula C10H17N6O12P3
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SMILES
OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](N)[C@@H]1O)(O)=O)(OP(O)(O)=O)=O
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Synonyms
2'-Amino-2'-deoxyadenosine-5'-triphosphate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8. [Content Brief]
[3]. Aström H, et, al. Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides. J Am Chem Soc. 2004 Nov 17;126(45):14710-1. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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