2'-NH2-ATP tetrasodium
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) tetrasodium, an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling.
For research use only. We do not sell to patients.
- Formula: C10H13N6Na4O12P3
- Molecular Weight:594.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2'-NH2-ATP (2 mM) tetrasodium dose not replace ATP as a substrate for NH3-dependent cytidine 5'-triphosphate (CTP) formation catalyzed by CTP synthase[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 594.12
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Formula C10H13N6Na4O12P3
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SMILES
O=P(OP(O[Na])(O[Na])=O)(O[Na])OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](N)[C@@H]1O)(O[Na])=O
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Synonyms
2'-Amino-2'-deoxyadenosine-5'-triphosphate tetrasodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Armstrong VW, et al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8. [Content Brief]
[3]. Aström H, et al. Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides. J Am Chem Soc. 2004 Nov 17;126(45):14710-1. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2'-NH2-ATP tetrasodium Related Classifications
HY-131760A Related Classifications
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