2-Chloro-ADP sodium solution (10 mM)
2-Chloro-ADP (2-Chloroadenosine 5′-diphosphate) sodium (10 mM) is a Adenosine 5'-diphosphate (ADP; HY-W010918) derivative that induces human platelet aggregation and inhibits stimulated adenylate cyclase. 2-Chloro-ADP sodium (10 mM) inhibits mortalin nucleotide-binding domain (NBD) with a Ki of 45.05 μM.
For research use only. We do not sell to patients.
- CAS No.: 82927-78-4
- Formula: C10H11ClN5Na3O10P2
- Molecular Weight:527.59
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Storage:
Solution, -20°C, 2 years
Biological Activity
Chemical Information
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CAS No. 82927-78-4
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Appearance Liquid
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Molecular Weight 527.59
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Formula C10H11ClN5Na3O10P2
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Color Colorless to light yellow
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C3=NC(Cl)=NC(N)=C3N=C2)O[C@@H]1COP(OP(O[Na])(O[Na])=O)(O[Na])=O
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Synonyms
2-Chloroadenosine 5′-diphosphate sodium solution (10 mM)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. N J Cusack, et al. Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate. Br J Pharmacol. 1982 Oct;77(2):329-33. [Content Brief]
[2]. Mitchell A Moseng, et al. 2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin. FEBS Lett. 2019 Aug;593(15):2030-2039. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)