2-Chloro-ADP
2-Chloro-ADP (2-Chloroadenosine 5′-diphosphate) sis a Adenosine 5'-diphosphate (ADP; HY-W010918) derivative that induces human platelet aggregation and inhibits stimulated adenylate cyclase. 2-Chloro-ADP inhibits mortalin nucleotide-binding domain (NBD) with a Ki of 45.05 μM.
For research use only. We do not sell to patients.
- CAS No.: 16506-88-0
- Formula: C10H14ClN5O10P2
- Molecular Weight:461.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 16506-88-0
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Molecular Weight 461.65
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Formula C10H14ClN5O10P2
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SMILES
O[C@H]1[C@@H](O)[C@H](N2C3=NC(Cl)=NC(N)=C3N=C2)O[C@@H]1COP(OP(O)(O)=O)(O)=O
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Synonyms
2-Chloroadenosine 5′-diphosphate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. N J Cusack, et al. Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate. Br J Pharmacol. 1982 Oct;77(2):329-33. [Content Brief]
[2]. Mitchell A Moseng, et al. 2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin. FEBS Lett. 2019 Aug;593(15):2030-2039. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Chloro-ADP Related Classifications
HY-131776 Related Classifications
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