2-Acetylbenzoic acid

Cat. No.: HY-N1717 Purity: 99.86%: Data Sheet
COA

SDS
Handling Instructions
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2-Acetylbenzoic acid, a Benzoic acid (HY-N0216) derivative, is a weak platelet aggregation inhibitor. 2-Acetylbenzoic acid inhibits Adenosine 5'-diphosphate (ADP, HY-W010918)-induced platelet aggregation.

For research use only. We do not sell to patients.

2-Acetylbenzoic acid Chemical Structure

CAS No. : 577-56-0

Size	Stock	Quantity
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Biological Activity
Purity & Documentation
References
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Description

Cellular Effect

Cell Line	Type	Value	Description	References
B16-F10	IC₅₀	852 μM Compound: 2AcBH	Cytotoxicity against mouse B16F10 cells assessed as cell viability after 72 hrs by MTT assay Cytotoxicity against mouse B16F10 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26774931]
K562	IC₅₀	501.7 μM Compound: 2AcBH	Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by tryphan blue assay Cytotoxicity against human K562 cells assessed as cell viability after 72 hrs by tryphan blue assay	[PMID: 26774931]
L929	IC₅₀	473.8 μM Compound: 2AcBH	Cytotoxicity against mouse L929 cells assessed as cell viability after 72 hrs by MTT assay Cytotoxicity against mouse L929 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26774931]
Melan-a	IC₅₀	774.8 μM Compound: 2AcBH	Cytotoxicity against mouse Melan-a cells assessed as cell viability after 72 hrs by MTT assay Cytotoxicity against mouse Melan-a cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26774931]

Molecular Weight

164.16

Formula

C₉H₈O₃

CAS No.

577-56-0

Appearance

Solid

Color

Off-white to yellow

SMILES

O=C(C1=C(C(C)=O)C=CC=C1)O

Structure Classification

Ketones, Aldehydes, Acids

Others

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Purity & Documentation

Purity: 99.87%

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Data Sheet (269 KB) SDS (393 KB)

COA (252 KB) HNMR (121 KB) RP-HPLC (210 KB)

Handling Instructions (2659 KB)

References

[1]. Cerskus I, et al. Relationship of inhibition of prostaglandin synthesis in platelets to anti-aggregatory and anti-inflammatory activity of some benzoic acid derivatives. Agents Actions. 1981 May;11(3):281-6. [Content Brief]