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Results for "

oxytocin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Oxytocin Receptor (77) Adenylate Cyclase (1) Adrenergic Receptor (1) Amino Acid Derivatives (1) Drug Derivative (2) Endogenous Metabolite (7) Isotope-Labeled Compounds (4) mAChR (3) Melanocortin Receptor (1) Opioid Receptor (1) P-glycoprotein (1) Potassium Channel (1) Reference Standards (5) Vasopressin Receptor (20)
By Research Areas:	Cancer (9) Cardiovascular Disease (11) Endocrinology (59) Metabolic Disease (10) Neurological Disease (27)

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Targets Recommended: Oxytocin Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17571

*Oxytocin* Maximum Cited Publications 27 Publications Verification α-Hypophamine; Oxytocic hormone	Oxytocin Receptor Endogenous Metabolite	Endocrinology Cancer
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .

HY-17571A

Oxytocin acetate Maximum Cited Publications 27 Publications Verification α-Hypophamine acetate; Oxytocic hormone acetate	Oxytocin Receptor Endogenous Metabolite	Endocrinology Cancer
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .

HY-17572

Atosiban 5+ Cited Publications RW22164; RWJ22164	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive *vasopressin/oxytocin* receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-108677

L-368,899 hydrochloride 5+ Cited Publications	Oxytocin Receptor	Endocrinology
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC₅₀s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .

HY-17573

Carbetocin 2 Publications Verification	Oxytocin Receptor	Neurological Disease Endocrinology
Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K_i of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K_i=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .

HY-124733A

LIT-001	Oxytocin Receptor	Neurological Disease
LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC₅₀=55 nM; K_i=226 nM). LIT-001 improves social interaction in a mouse model of autism .

HY-P3467

(Thr4,Gly7)-Oxytocin 3 Publications Verification	Oxytocin Receptor Potassium Channel	Neurological Disease
(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K ⁺ channels. .

HY-15023

Cligosiban 5+ Cited Publications PF-3274167	Oxytocin Receptor	Endocrinology
Cligosiban (PF-3274167) is an orally active, highly selective, and centrally permeable oxytocin receptor antagonist with good pharmacokinetics in rats and can inhibit physiological ejaculation in rodents ^[1][2].

HY-15522

WAY-267464 2 Publications Verification	Oxytocin Receptor	Neurological Disease
WAY-267464 is a non-peptide oxytocin receptor (OTR) agonist. WAY-267464 can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder .

HY-W048739

Fmoc-α-Me-Leu-OH	Amino Acid Derivatives	Others
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .

HY-17572A

Atosiban acetate 5+ Cited Publications RW22164 acetate; RWJ22164 acetate	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive *vasopressin/oxytocin* receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-P2168

Demoxytocin	Oxytocin Receptor Drug Derivative	Metabolic Disease
Demoxytocin is a heterologous cyclic peptide and an analog of Oxytocin (HY-17571). Demoxytocin affects the permeability of cell membranes and increases calcium ion levels in smooth muscle cells, thereby enhancing the contraction of smooth muscle cells. Demoxytocin also stimulates the contraction of uterine smooth muscle. Demoxytocin possesses the functions of oxytocin. Demoxytocin can be used to study labor stimulation in preterm premature rupture of membranes .

HY-15010

L-371,257 1 Publications Verification	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology
L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (K_i=19 nM) and vasopressin V1a receptor (K_i=3.7 nM) .

HY-17573A

Carbetocin acetate 2 Publications Verification	Oxytocin Receptor	Neurological Disease Endocrinology
Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K_i of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K_i=1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .

HY-W587861

5β-Dihydroprogesterone 1 Publications Verification 5βDHP	Oxytocin Receptor	Endocrinology
5β-Dihydroprogesterone (5βDHP) is the metabolite of Progesterone (HY-N0437). 5β-Dihydroprogesterone binds to oxytocin receptor, reduces the Oxytocin (HY-17571)-induced calcium signal transduction, thereby exhibiting the tocolytic activity .

HY-P0004

Lysipressin 2 Publications Verification Lysine vasopressin; [Lys8]-Vasopressin	Adenylate Cyclase Oxytocin Receptor	Cardiovascular Disease Neurological Disease
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-108679

WAY-267464 hydrochloride 2 Publications Verification	Oxytocin Receptor	Neurological Disease
WAY-267464 (hydrochloride) is a non-peptide oxytocin receptor (OTR) agonist. WAY-267464 (hydrochloride) can impair social recognition memory in rats through a vasopressin 1A receptor antagonist action. WAY-267464 (hydrochloride) can be used for the research of psychiatric disorders, such disorders include autism spectrum disorder, schizophrenia, and social anxiety disorder .

HY-P4990

Pro8-Oxytocin	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

HY-14778

Retosiban GSK 221149; GSK 221149A	Oxytocin Receptor	Neurological Disease Endocrinology
Retosiban (GSK221149A) is a potent, selective, and orally active oxytocin receptor antagonist (K_i (hOT) = 0.65 nM, K_i (rOT) = 4.1 nM) with no detectable agonist activity. Retosiban has nanomolar affinity for the oxytocin receptor with >1400-fold selectivity over the closely related vasopressin receptors. Retosiban inhibits spontaneous and induces uterine contractions. Retosiban can be studied in research for preterm labour .

HY-B0962A

Piperidolate	mAChR	Cardiovascular Disease
Piperidolate is a cholinergic antagonist. Piperidolate prevents ventricular fibrillation during hypothermic cardiac manipulations to support cardiac procedures post-preoperative defibrillation. Piperidolate causes dose-dependent cardiac depression. Piperidolate can be used for the research of ventricular fibrillation .

HY-B0962

Piperidolate hydrochloride	mAChR	Cardiovascular Disease
Piperidolate hydrochloride is a cholinergic antagonist. Piperidolate hydrochloride prevents ventricular fibrillation during hypothermic cardiac manipulations to support cardiac procedures post-preoperative defibrillation. Piperidolate hydrochloride causes dose-dependent cardiac depression. Piperidolate hydrochloride can be used for the research of ventricular fibrillation .

HY-P3215

Oxytocin parallel dimer	Oxytocin Receptor	Endocrinology
Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .

HY-P3221

[Leu3]-Oxytocin	Oxytocin Receptor	Endocrinology
[Leu3]-Oxytocin, an oxytocin analogue, is derived by structural variation in sequence position 3 replaced by leucine (Leu) .

HY-P4990A

*Pro8-Oxytocin* TFA**	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin TFA is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin TFA produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

HY-P4605

(Ile8)-Oxytocin Mesotocin	Endogenous Metabolite	Metabolic Disease
(Ile8)-Oxytocin is a neurohypophysial hormone mesotocin produced in marsupials .

HY-153963

PF-06655075	Oxytocin Receptor	Endocrinology
PF-06655075 is a novel andnon–brain-penetrant oxytocin receptor agonist with increased selectivity for the oxytocin receptor and significantly increased pharmacokinetic stability. PF-06655075 can be used as a tool compound to further explore the role of peripheral oxytocin in behavioral response .

HY-108678

TC OT 39	Oxytocin Receptor Vasopressin Receptor	Neurological Disease
TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC₅₀=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an K_i value of 330 nM. TC OT 39 exhibits sedative effects in mouse models .

HY-128351

SHR1653 1 Publications Verification	Oxytocin Receptor	Neurological Disease Endocrinology
SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC₅₀ of 15 nM for hOTR .

HY-P1390

d[Cha4]-AVP	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a K_i of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P3217A

*[Asp5]-Oxytocin* acetate**	Oxytocin Receptor	Endocrinology
[Asp5]-Oxytocin acetate is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin acetate causes uterine contractions in vitro, enhanced by Mg ²⁺. [Asp5]-Oxytocin acetate has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic .

HY-P4678

(Phe2,Orn8)-Oxytocin	Vasopressin Receptor	Neurological Disease
(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC₅₀ value of 280 nM .

HY-17571F

Biotin-Oxytocin Biotin-α-Hypophamine; Biotin-Oxytocic hormone	Oxytocin Receptor	Others
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.)

HY-P2626

[D-Ala2]-Met-Enkephalin	Opioid Receptor	Neurological Disease
[D-Ala2]-Met-Enkephalin, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalin inhibits ACh-induced and suckling-induced oxytocin (OT) release .

HY-P4397

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

HY-P3516

Barusiban FE-200440	Oxytocin Receptor	Endocrinology
Barusiban (FE-200440) is an oxytocin receptor (OT-R) antagonist (K_i=0.8 nM), inhibits OT-induced contraction. Barusiban can be used in preterm labor (PTL), in vitro fertilisation (IVF) and infertility research .

HY-P3219

N-Acetyloxytocin	Endogenous Metabolite	Endocrinology
N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat .

HY-P3218A

*[Glu4]-Oxytocin* acetate**	Drug Derivative	Endocrinology
[Glu4]-Oxytocin acetate is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of oxytocin-like molecules in aqueous solution .

HY-P3866

[Asu1,6]-Oxytocin	Oxytocin Receptor	Metabolic Disease
[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes .

HY-P4605A

*(Ile8)-Oxytocin* acetate**	Endogenous Metabolite	Metabolic Disease
(Ile8)-Oxytocin acetate is a neurohypophysial hormone interoxitocin produced in marsupials .

HY-P3216

Oxytocin free acid 9-Deamidooxytocin	Oxytocin Receptor	Endocrinology
Oxytocin free acid (9-Deamidooxytocin) is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior .

HY-P3216B

Oxytocin free acid TFA 15+ Cited Publications 9-Deamidooxytocin TFA	Oxytocin Receptor	Endocrinology
Oxytocin free acid (9-Deamidooxytocin) TFA is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior .

HY-15008

L-368,899	Oxytocin Receptor	Endocrinology
L-368,899 is an orally active and selective *OT (oxytocin* ) receptor antagonist, with IC₅₀*s of 8.9 and 26 nM for uterus of rat and human, respectively. L-368,899 can cross the blood-brain barrier (BBB). L-368,899 inhibits oxytocin*-stimulated uterine contractions in rats and can be used in study of preterm labor .

HY-P4895

(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-P3218

[Glu4]-Oxytocin	Oxytocin Receptor	Endocrinology
[Glu4]-Oxytocin is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of “oxytocin-like” molecules in aqueous solution .

HY-P3217

[Asp5]-Oxytocin	Oxytocin Receptor	Endocrinology
[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin causes uterine contractions in vitro, enhanced by Mg ²⁺. [Asp5]-Oxytocin has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic .

HY-16741

Erlosiban OBE001	Oxytocin Receptor	Endocrinology
Erlosiban (OBE001) is an orally active non-peptide type oxytocin receptor antagonist. Erlosiban inhibits the increase of intracellular calcium concentration, thereby reducing uterine smooth muscle contraction. Erlosiban can be used for research on premature birth and to improve embryo implantation and pregnancy rate in assisted reproductive technology (AR).

HY-105018

Epelsiban GSK 557296	Oxytocin Receptor	Endocrinology
Epelsiban (GSK 557296) is a potent, selective and orally bioavailable oxytocin receptor antagonist, with a pK_i of 9.9 for human oxytocin receptor.

HY-P1574A

[Arg8]-Vasotocin TFA Vasotocin TFA; Argiprestocin TFA; Arginine vasotocin TFA	Vasopressin Receptor Oxytocin Receptor	Neurological Disease
[Arg8]-Vasotocin (TFA) is a vertebrate neurohypophyseal peptide of the vasopressin/oxytocin hormone family .

HY-P0077

Merotocin	Oxytocin Receptor	Endocrinology
Merotocin is a selective, short-acting peptidic *oxytocin* receptor agonist. Merotocin can be used to support lactation .

HY-P10325

Kalata B7	Vasopressin Receptor Oxytocin Receptor	Cardiovascular Disease
Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of *oxytocin* and vasopressin V_1a receptors .

Cat. No.	Product Name	Target	Research Area

HY-17571

*Oxytocin* Maximum Cited Publications 27 Publications Verification α-Hypophamine; Oxytocic hormone	Oxytocin Receptor Endogenous Metabolite	Endocrinology Cancer
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .

HY-17571A

Oxytocin acetate Maximum Cited Publications 27 Publications Verification α-Hypophamine acetate; Oxytocic hormone acetate	Oxytocin Receptor Endogenous Metabolite	Endocrinology Cancer
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .

HY-17572

Atosiban 5+ Cited Publications RW22164; RWJ22164	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban (RW22164; RWJ22164) is a nonapeptide competitive *vasopressin/oxytocin* receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-17573

Carbetocin 2 Publications Verification	Oxytocin Receptor	Neurological Disease Endocrinology
Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K_i of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K_i=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .

HY-P3467

(Thr4,Gly7)-Oxytocin 3 Publications Verification	Oxytocin Receptor Potassium Channel	Neurological Disease
(Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K ⁺ channels. .

HY-W048739

Fmoc-α-Me-Leu-OH	Amino Acid Derivatives	Others
Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .

HY-17572A

Atosiban acetate 5+ Cited Publications RW22164 acetate; RWJ22164 acetate	Oxytocin Receptor Vasopressin Receptor	Cardiovascular Disease Endocrinology Cancer
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive *vasopressin/oxytocin* receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

HY-P2168

Demoxytocin	Oxytocin Receptor Drug Derivative	Metabolic Disease
Demoxytocin is a heterologous cyclic peptide and an analog of Oxytocin (HY-17571). Demoxytocin affects the permeability of cell membranes and increases calcium ion levels in smooth muscle cells, thereby enhancing the contraction of smooth muscle cells. Demoxytocin also stimulates the contraction of uterine smooth muscle. Demoxytocin possesses the functions of oxytocin. Demoxytocin can be used to study labor stimulation in preterm premature rupture of membranes .

HY-17573A

Carbetocin acetate 2 Publications Verification	Oxytocin Receptor	Neurological Disease Endocrinology
Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K_i of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K_i=1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .

HY-P0004

Lysipressin 2 Publications Verification Lysine vasopressin; [Lys8]-Vasopressin	Adenylate Cyclase Oxytocin Receptor	Cardiovascular Disease Neurological Disease
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

HY-P4990

Pro8-Oxytocin	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

HY-P3222

Oxytocin antiparallel dimer	Peptides	Endocrinology
Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .

HY-P3215

Oxytocin parallel dimer	Oxytocin Receptor	Endocrinology
Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .

HY-P3221

[Leu3]-Oxytocin	Oxytocin Receptor	Endocrinology
[Leu3]-Oxytocin, an oxytocin analogue, is derived by structural variation in sequence position 3 replaced by leucine (Leu) .

HY-P4990A

*Pro8-Oxytocin* TFA**	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin TFA is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin TFA produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

HY-P4605

(Ile8)-Oxytocin Mesotocin	Endogenous Metabolite	Metabolic Disease
(Ile8)-Oxytocin is a neurohypophysial hormone mesotocin produced in marsupials .

HY-153963

PF-06655075	Oxytocin Receptor	Endocrinology
PF-06655075 is a novel andnon–brain-penetrant oxytocin receptor agonist with increased selectivity for the oxytocin receptor and significantly increased pharmacokinetic stability. PF-06655075 can be used as a tool compound to further explore the role of peripheral oxytocin in behavioral response .

HY-P1390

d[Cha4]-AVP	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP is a potent and selective vasopressin (AVP) V1b receptor agonist with a K_i of 1.2 nM for human V1b receptor. d[Cha4]-AVP shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P3217A

*[Asp5]-Oxytocin* acetate**	Oxytocin Receptor	Endocrinology
[Asp5]-Oxytocin acetate is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin acetate causes uterine contractions in vitro, enhanced by Mg ²⁺. [Asp5]-Oxytocin acetate has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic .

HY-P4678

(Phe2,Orn8)-Oxytocin	Vasopressin Receptor	Neurological Disease
(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC₅₀ value of 280 nM .

HY-17571F

Biotin-Oxytocin Biotin-α-Hypophamine; Biotin-Oxytocic hormone	Oxytocin Receptor	Others
Biotin-Oxytocin (Biotin-α-Hypophamine; Biotin-Oxytocic hormone) is a biological active peptide. (This is Oxytocin (HY-17571) N-terminally labeled with Biotin.)

HY-P2626

[D-Ala2]-Met-Enkephalin	Opioid Receptor	Neurological Disease
[D-Ala2]-Met-Enkephalin, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalin inhibits ACh-induced and suckling-induced oxytocin (OT) release .

HY-P4397

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin	Oxytocin Receptor	Endocrinology
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, an oxytocin receptor antagonist, abolishes oxytocin-enhanced inhibitory postsynaptic currents in CA1 pyramidal neurons .

HY-P3516

Barusiban FE-200440	Oxytocin Receptor	Endocrinology
Barusiban (FE-200440) is an oxytocin receptor (OT-R) antagonist (K_i=0.8 nM), inhibits OT-induced contraction. Barusiban can be used in preterm labor (PTL), in vitro fertilisation (IVF) and infertility research .

HY-P3219

N-Acetyloxytocin	Endogenous Metabolite	Endocrinology
N-Acetyloxytocin is isolated and characterized in the neurointermediate lobe of the rat pituitary (NIL) and their presence in several brain areas of the rat .

HY-P3218A

*[Glu4]-Oxytocin* acetate**	Drug Derivative	Endocrinology
[Glu4]-Oxytocin acetate is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of oxytocin-like molecules in aqueous solution .

HY-P3866

[Asu1,6]-Oxytocin	Oxytocin Receptor	Metabolic Disease
[Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes .

HY-P4605A

*(Ile8)-Oxytocin* acetate**	Endogenous Metabolite	Metabolic Disease
(Ile8)-Oxytocin acetate is a neurohypophysial hormone interoxitocin produced in marsupials .

HY-P3216

Oxytocin free acid 9-Deamidooxytocin	Oxytocin Receptor	Endocrinology
Oxytocin free acid (9-Deamidooxytocin) is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior .

HY-P3216B

Oxytocin free acid TFA 15+ Cited Publications 9-Deamidooxytocin TFA	Oxytocin Receptor	Endocrinology
Oxytocin free acid (9-Deamidooxytocin) TFA is an analog of oxytocin in which the glycinamide residue at position 9 in oxytocin has been replaced by a glycine residue. Oxytocin is a pleiotropic, peptide hormone with broad implications for general health, adaptation, development, reproduction, and social behavior .

HY-P4184

Isotocin (Ser4,Ile8)-oxytocin	Peptides	Others
Isotocin ((Ser4,Ile8)-Oxytocin) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4895

(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin (OVT) is an oxytocin receptor antagonist. (d(CH2)51,Tyr(Me)2,Orn8)-Oxytocin can be used for the research of neurological disease .

HY-P3218

[Glu4]-Oxytocin	Oxytocin Receptor	Endocrinology
[Glu4]-Oxytocin is an appropriate derivative of oxytocin for conducting a comprehensive investigation by a variety of methods of the conformation of “oxytocin-like” molecules in aqueous solution .

HY-P3217

[Asp5]-Oxytocin	Oxytocin Receptor	Endocrinology
[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin causes uterine contractions in vitro, enhanced by Mg ²⁺. [Asp5]-Oxytocin has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic .

HY-P1574A

[Arg8]-Vasotocin TFA Vasotocin TFA; Argiprestocin TFA; Arginine vasotocin TFA	Vasopressin Receptor Oxytocin Receptor	Neurological Disease
[Arg8]-Vasotocin (TFA) is a vertebrate neurohypophyseal peptide of the vasopressin/oxytocin hormone family .

HY-P0077

Merotocin	Oxytocin Receptor	Endocrinology
Merotocin is a selective, short-acting peptidic *oxytocin* receptor agonist. Merotocin can be used to support lactation .

HY-P10325

Kalata B7	Vasopressin Receptor Oxytocin Receptor	Cardiovascular Disease
Kalata B7 is a cyclotide that can be isolated from Oldenlandia affinis DC (Rubiaceae) and possesses membrane-permeating capabilities. Kalata B7 is also a partial agonist of *oxytocin* and vasopressin V_1a receptors .

HY-P1390A

d[Cha4]-AVP TFA	Vasopressin Receptor	Endocrinology
d[Cha4]-AVP TFA is a potent and selective vasopressin (AVP) V1b receptor agonist with a K_i of 1.2 nM for human V1b receptor. d[Cha4]-AVP TFA shows more selective for V1b receptor than human V1a receptor, V2 receptor, and oxytocin receptors .

HY-P4994

Val9-Oxytocin	Vasopressin Receptor	Cardiovascular Disease
Val9-Oxytocin is a full antagonist of vasopressin (V_1a) receptor. Val9-Oxytocin is an analog of Oxytocin (HY-17571A) in which changing Gly9 to Val9 .

HY-P3220

[D-Asn5]-Oxytocin	Oxytocin Receptor	Endocrinology
[D-Asn5]-Oxytocin possesses very low specific oxytocic and vasodepressor activities. By cumulative dose-response studies for oxytocic activity, [D-Asn5]-Oxytocin has similar intrinsic activity to oxytocin .

HY-P3215A

Oxytocin parallel dimer TFA	Oxytocin Receptor	Endocrinology
Oxytocin parallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .

HY-P3222A

Oxytocin antiparallel dimer TFA	Peptides	Endocrinology
Oxytocin antiparallel dimer TFA is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin .

HY-P5017

(Val3,Pro8)-Oxytocin	Oxytocin Receptor	Endocrinology
(Val3,Pro8)-Oxytocin is the Gq-dependent pathway agonist. (Val3,Pro8)-Oxytocin is also a weaker agonist for the β-arrestin engagement and endocytosis toward the oxytocin receptor (OXTR) .

HY-P4678A

*(Phe2,Orn8)-Oxytocin* acetate**	Vasopressin Receptor	Neurological Disease
(Phe2,Orn8)-Oxytocin acetate is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin acetate induces a sustained contractility of rabbit epididymis with EC₅₀ value of 280 nM .

HY-P2034

Cargutocin	Oxytocin Receptor	Endocrinology
Cargutocin, an oxytocin analogue, targets the oxytocin receptor and acts as a uterine contraction agent .

HY-P4184A

Isotocin acetate (Ser4,Ile8)-oxytocin acetate	Peptides	Others
Isotocin (acetate) ((Ser4,Ile8)-Oxytocin (acetate)) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-153963A

PF-06655075 TFA	Oxytocin Receptor	Endocrinology
PF-06655075 (TFA) is the TFA form of PF-06655075 (HY-153963). PF-06655075 is a novel andnon–brain-penetrant oxytocin receptor agonist with increased selectivity for the oxytocin receptor and significantly increased pharmacokinetic stability. PF-06655075 can be used as a tool compound to further explore the role of peripheral oxytocin in behavioral response .

HY-P11144

Inotocin	Peptides	Neurological Disease
Inotocin is a neuropeptide belonging to the oxytocin/vasopressin family in insects. Inotocin does not participate in water balance regulation. Inotocin may regulate reproductive behavior, especially parental care .

HY-P2014

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin	Oxytocin Receptor	Neurological Disease
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,Tyr-NH29)-Vasotocin is an *oxytocin* antagonist and can be used for the research of sexual behavior .

HY-17572R

Atosiban (Standard) RW22164 (Standard); RWJ22164 (Standard)	Reference Standards Oxytocin Receptor Vasopressin Receptor	Endocrinology Cancer
Atosiban (Standard) is the analytical standard of Atosiban. This product is intended for research and analytical applications. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive *vasopressin/oxytocin* receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17571

*Oxytocin* Maximum Cited Publications 27 Publications Verification α-Hypophamine; Oxytocic hormone	Natural Products Monophenols Animals Classification of Application Fields Phenols Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Oxytocin Receptor Endogenous Metabolite
Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .

HY-17571A

Oxytocin acetate Maximum Cited Publications 27 Publications Verification α-Hypophamine acetate; Oxytocic hormone acetate	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification Cancer	Oxytocin Receptor Endogenous Metabolite
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma .

HY-P0004

Lysipressin 2 Publications Verification Lysine vasopressin; [Lys8]-Vasopressin	Monophenols Animals Classification of Application Fields Other Diseases Phenols Disease Research Fields Source Classification	Adenylate Cyclase Oxytocin Receptor
Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity .

Recombinant Proteins Recommended:

Oxytocin

Species:	Human (2)
Tag:	His (2) Flag (1)
Source:	Sf9 insect cells (1) P. pastoris (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71766

	OXT Protein, Human (P.pastoris, His) OXT; OT; oxytocin-neurophysin 1	Human	P. pastoris
	OXT, or oxytocin, induces physiological effects by binding to neurophysin 1 and interacting with the oxytocin receptor (OXTR). This interaction results in smooth muscle contraction in the uterus and mammary gland, crucial for labor and breastfeeding, respectively, by modulating OXTR activity. OXT Protein, Human (P.pastoris, His) is the recombinant human-derived OXT protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P703171

	OXYR Protein, Human (sf9, Flag, His) oxytocin receptor; OXTR; Homo sapiens; Human; OT-R; G-protein coupled receptor; Receptor; Transducer	Human	Sf9 insect cells
	OXYR Protein, Human (sf9, Flag, His) is the recombinant human-derived OXYR, expressed by sf9 insect cells , with His, Flag labeled tag. ,

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Cat. No.	Product Name	Chemical Structure

HY-17571BS

Oxytocin-d10 TFA

Oxytocin-d₁₀ TFA (α-Hypophamine-d₁₀ TFA) is the deuterium labeled Oxytocin TFA (HY-17571B). Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma.

HY-17571S

Oxytocin-13C6,15N TFA

Oxytocin- ¹³C₆, ¹⁵N (α-Hypophamine- ¹³C₆, ¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled Oxytocin TFA. Oxytocin (α-Hypophamine; Oxytocic hormone) is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma.

HY-17573S

Carbetocin-d7

Carbetocin-d₇ is the deuterium labeled Carbetocin (HY-17573). Carbetocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K_i of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K_i=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS .

HY-17572S

Atosiban-d5 TFA
Atosiban-d₅ TFA (RW22164-d₅ TFA) is the deuterium labeled Atosiban TFA. Atosiban (RW22164; RWJ22164) is a nonapeptide competitive *vasopressin/oxytocin* receptor** antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research .

Host:	Guinea pig (1) Rabbit (5)
Reactivity:	Human (5) Rat (4) Mouse (4)
Application:	IHC-P (4) ICC/IF (2) IF-Tissue (4) WB (3) IHC-F (4) ELISA (3)
Isotype:	IgG (5)
Conjugation:	Non-conjugated (6)
Clonality:	Polyclonal (3) Monoclonal (3) Recombinant (3)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P810307

	Oxytocin Antibody OXT, Neurophysin 1, Ocytocin Neurophysin 1, oxytocin, oxytocin neurophysin 1	IHC-P, IHC-F, ICC/IF, ELISA, IF-Tissue	Human
	Oxytocin Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Oxytocin.

HY-P810307A

	Oxytocin Antibody (PBS Only) OXT, Neurophysin 1, Ocytocin Neurophysin 1, oxytocin, oxytocin neurophysin 1	IHC-P, IHC-F, ICC/IF, ELISA, IF-Tissue	Human
	Oxytocin Antibody (PBS Only) is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Oxytocin.

HY-P87000

	Oxytocin-neurophysin 1/OXT Antibody (YA6693) MGC126890 antibody; MGC126892 antibody; Neurophysin 1 antibody; Neurophysin I antibody; Ocytocin antibody; OT antibody; OT NPI antibody; OXT antibody; oxytocin antibody; oxytocin Neurophysin preproprotein antibody; MGC126890 antibody; MGC126892 antibody; Neurophysin 1 antibody; Neurophysin I antibody; Ocytocin antibody; OT antibody; OT NPI antibody; OXT antibody; oxytocin antibody; oxytocin Neurophysin preproprotein antibody; oxytocin prepro (neurophysin I) antibody; oxytocin prepropeptide antibody; oxytocin-neurophysin 1 antibody;	IHC-F, IF-Tissue	Mouse, Rat
	Oxytocin-neurophysin 1/OXT Antibody (YA6693) is a Guinea pig-derived and non-conjugated monoclonal antibody, targeting to Oxytocin-neurophysin 1/OXT.

HY-P87001

	Oxytocin-neurophysin 1/OXT Antibody (YA6694) MGC126890 antibody; MGC126892 antibody; Neurophysin 1 antibody; Neurophysin I antibody; Ocytocin antibody; OT antibody; OT NPI antibody; OXT antibody; oxytocin antibody; oxytocin Neurophysin preproprotein antibody; MGC126890 antibody; MGC126892 antibody; Neurophysin 1 antibody; Neurophysin I antibody; Ocytocin antibody; OT antibody; OT NPI antibody; OXT antibody; oxytocin antibody; oxytocin Neurophysin preproprotein antibody; oxytocin prepro (neurophysin I) antibody; oxytocin prepropeptide antibody; oxytocin-neurophysin 1 antibody;	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
	Oxytocin-neurophysin 1/OXT Antibody (YA6694) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Oxytocin-neurophysin 1/OXT.

HY-P81145

	Oxytocin Receptor Antibody OXYR_HUMAN; oxytocin receptor; OXTR; OTR1; OT-R; OTR; OT R; OTR 1; OXT R;	WB, ELISA, IHC-P	Human, Mouse, Rat
	Oxytocin Receptor Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Oxytocin Receptor.

HY-P82615

	Oxytocin Receptor Antibody (YA2360) OT R; OTR; OTR1; OXT R; Oxtr	WB	Human, Mouse, Rat
	Oxytocin Receptor Antibody (YA2360) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Oxytocin Receptor.

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