1. GPCR/G Protein
  2. Oxytocin Receptor

Retosiban (Synonyms: GSK 221149; GSK 221149A)

Cat. No.: HY-14778
Handling Instructions

Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a Ki of 0.65 nM.

For research use only. We do not sell to patients.

Retosiban Chemical Structure

Retosiban Chemical Structure

CAS No. : 820957-38-8

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a Ki of 0.65 nM.

IC50 & Target

IC50: 0.65 nM (Oxytocin)[1]

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0219 mL 10.1096 mL 20.2192 mL
5 mM 0.4044 mL 2.0219 mL 4.0438 mL
10 mM 0.2022 mL 1.0110 mL 2.0219 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

494.58

Formula

C₂₇H₃₄N₄O₅

CAS No.

820957-38-8

SMILES

O=C([[email protected]@H](C1CC2=C(C=CC=C2)C1)N3)N([[email protected]](C4=COC(C)=N4)C(N5CCOCC5)=O)[[email protected]]([[email protected]](CC)C)C3=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Retosiban
Cat. No.:
HY-14778
Quantity:

Retosiban

Cat. No.: HY-14778