[Asp5]-Oxytocin acetate
Based on 1 Customer Validation
[Asp5]-Oxytocin acetate is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin acetate causes uterine contractions in vitro, enhanced by Mg2+. [Asp5]-Oxytocin acetate has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic.
For research use only. We do not sell to patients.
- Purity: 99.51%
- Formula: C45H69N11O15S2
- Molecular Weight:1068.22
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
![[Asp5]-Oxytocin acetate Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p3217a.gif "Click to View [Asp5]-Oxytocin acetate Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
[Asp5]-Oxytocin acetate retains not only a high affinity for the uterotonic receptor, but also an intrinsic activity identical with that of oxytocin[1].
[Asp5]-Oxytocin acetate displays an increasing intrinsic activity enhanced by 1 mM Mg2+[1].
[Asp5]-Oxytocin acetate exerts the same potencies of rat uterotonic, avian vasodepressor, and rat antidiuretic with 20.3, 41, and 0.14 units/mg dose[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1068.22
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Formula C45H69N11O15S2
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Color White to off-white
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Sequence
Cys-Tyr-Ile-Gln-Asp-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6)
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Sequence Shortening
CYIQDCPLG-NH2 (Disulfide bridge:Cys1-Cys6)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (93.61 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (284 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9361 mL | 4.6807 mL | 9.3614 mL | 23.4034 mL |
| 5 mM | 0.1872 mL | 0.9361 mL | 1.8723 mL | 4.6807 mL | |
| 10 mM | 0.0936 mL | 0.4681 mL | 0.9361 mL | 2.3403 mL | |
| 15 mM | 0.0624 mL | 0.3120 mL | 0.6241 mL | 1.5602 mL | |
| 20 mM | 0.0468 mL | 0.2340 mL | 0.4681 mL | 1.1702 mL | |
| 25 mM | 0.0374 mL | 0.1872 mL | 0.3745 mL | 0.9361 mL | |
| 30 mM | 0.0312 mL | 0.1560 mL | 0.3120 mL | 0.7801 mL | |
| 40 mM | 0.0234 mL | 0.1170 mL | 0.2340 mL | 0.5851 mL | |
| 50 mM | 0.0187 mL | 0.0936 mL | 0.1872 mL | 0.4681 mL | |
| 60 mM | 0.0156 mL | 0.0780 mL | 0.1560 mL | 0.3901 mL | |
| 80 mM | 0.0117 mL | 0.0585 mL | 0.1170 mL | 0.2925 mL |
[Asp5]-Oxytocin acetate Related Classifications
HY-P3217A Related Classifications
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