[Asp5]-Oxytocin
Based on 1 Customer Validation
[Asp5]-Oxytocin is the first 5-position neurohypophyseal hormone analogue possessing significant biological activity. [Asp5]-Oxytocin causes uterine contractions in vitro, enhanced by Mg2+. [Asp5]-Oxytocin has the ability of rat uteroconstrictor, avian vasodilator, and rat antidiuretic.
For research use only. We do not sell to patients.
- Purity: 99.51%
- CAS No.: 65907-78-0
- Formula: C43H65N11O13S2
- Molecular Weight:1008.17
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Storage:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
![[Asp5]-Oxytocin Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p3217.gif "Click to View [Asp5]-Oxytocin Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
[Asp5]-Oxytocin retains not only a high affinity for the uterotonic receptor, but also an intrinsic activity identical with that of oxytocin[1].
[Asp5]-Oxytocin displays an increasing intrinsic activity enhanced by 1 mM Mg2+[1].
[Asp5]-Oxytocin exerts the same potencies of rat uterotonic, avian vasodepressor, and rat antidiuretic with 20.3, 41, and 0.14 units/mg dose[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 65907-78-0
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Appearance Solid
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Molecular Weight 1008.17
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Formula C43H65N11O13S2
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Color White to off-white
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Sequence
Cys-Tyr-Ile-Gln-Asp-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6)
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Sequence Shortening
CYIQDCPLG-NH2 (Disulfide bridge:Cys1-Cys6)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (99.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9919 mL | 4.9595 mL | 9.9190 mL | 24.7974 mL |
| 5 mM | 0.1984 mL | 0.9919 mL | 1.9838 mL | 4.9595 mL | |
| 10 mM | 0.0992 mL | 0.4959 mL | 0.9919 mL | 2.4797 mL | |
| 15 mM | 0.0661 mL | 0.3306 mL | 0.6613 mL | 1.6532 mL | |
| 20 mM | 0.0496 mL | 0.2480 mL | 0.4959 mL | 1.2399 mL | |
| 25 mM | 0.0397 mL | 0.1984 mL | 0.3968 mL | 0.9919 mL | |
| 30 mM | 0.0331 mL | 0.1653 mL | 0.3306 mL | 0.8266 mL | |
| 40 mM | 0.0248 mL | 0.1240 mL | 0.2480 mL | 0.6199 mL | |
| 50 mM | 0.0198 mL | 0.0992 mL | 0.1984 mL | 0.4959 mL | |
| 60 mM | 0.0165 mL | 0.0827 mL | 0.1653 mL | 0.4133 mL | |
| 80 mM | 0.0124 mL | 0.0620 mL | 0.1240 mL | 0.3100 mL |
[Asp5]-Oxytocin Related Classifications
HY-P3217 Related Classifications
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