1. GPCR/G Protein
  2. Oxytocin Receptor
    Vasopressin Receptor
  3. L-371,257

L-371,257 

Cat. No.: HY-15010
Handling Instructions

L-371,257 is an orally bioavailable, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM).

For research use only. We do not sell to patients.

L-371,257 Chemical Structure

L-371,257 Chemical Structure

CAS No. : 162042-44-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 436 In-stock
Estimated Time of Arrival: December 31
5 mg USD 390 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Description

L-371,257 is an orally bioavailable, selective and competitive antagonist of oxytocin receptor (pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM)[1][2].

IC50 & Target

Ki: 19 nM (oxytocin receptor), 3.7 nM (vasopressin V1a receptor)[2]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

507.58

Formula

C₂₈H₃₃N₃O₆

CAS No.

162042-44-6

SMILES

O=C(OC1)N(C2CCN(C(C3=C(OC)C=C(OC4CCN(C(C)=O)CC4)C=C3)=O)CC2)C5=C1C=CC=C5

Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
L-371,257
Cat. No.:
HY-15010
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L-371,257

Cat. No.: HY-15010