2. GPCR/G Protein
  3. Oxytocin Receptor
  4. OT antagonist 1

OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.

For research use only. We do not sell to patients.

OT antagonist 1 Chemical Structure

OT antagonist 1 Chemical Structure

CAS No. : 479080-38-1

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OT antagonist 1 Related Antibodies

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Description

OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.

IC50 & Target

Ki: 50 nM (Oxytocin)[1]
In Vitro

Oxytocin (OT) is a nonapeptide hormone that acts on the OT receptor, a seven-transmembrane (7TM) (Gq-coupled) receptor. The OT receptor has no subtypes but is related to the vasopressin receptors V1A, V1B and V2. OT antagonists have therapeutic potential in a number of areas including pre-term labour: Benign Prostatic Hyperplasia and sexual dysfunction. As a result there is significant interest in the identification of potent, selective, orally bioavailable OT antagonists[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

OT antagonist 1 Related Antibodies
Molecular Weight

390.44

Formula

C22H22N4O3
CAS No.
SMILES

CC1=NOC([C@@H](N(C(C2=CC=C(C3=CC=CC=C3C)C=C2)=O)C/4)CC4=N/OC)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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OT antagonist 1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OT antagonist 1479080-38-1OT antagonist1OT antagonist-1Oxytocin ReceptorOXTRInhibitorinhibitorinhibit

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