1. GPCR/G Protein
  2. Oxytocin Receptor
  3. OT antagonist 1

OT antagonist 1 

Cat. No.: HY-103650
Handling Instructions

OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.

For research use only. We do not sell to patients.

OT antagonist 1 Chemical Structure

OT antagonist 1 Chemical Structure

CAS No. : 479080-38-1

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Description

OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.

IC50 & Target

Ki: 50 nM (Oxytocin)[1]

In Vitro

Oxytocin (OT) is a nonapeptide hormone that acts on the OT receptor, a seven-transmembrane (7TM) (Gq-coupled) receptor. The OT receptor has no subtypes but is related to the vasopressin receptors V1A, V1B and V2. OT antagonists have therapeutic potential in a number of areas including pre-term labour: Benign Prostatic Hyperplasia and sexual dysfunction. As a result there is significant interest in the identification of potent, selective, orally bioavailable OT antagonists[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

390.44

Formula

C₂₂H₂₂N₄O₃

CAS No.

479080-38-1

SMILES

CC1=NOC([[email protected]@H](N(C(C2=CC=C(C3=CC=CC=C3C)C=C2)=O)C/4)CC4=N/OC)=N1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
OT antagonist 1
Cat. No.:
HY-103650
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OT antagonist 1

Cat. No.: HY-103650