TC OT 39
Based on 1 Customer Validation
TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC50=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an Ki value of 330 nM. TC OT 39 exhibits sedative effects in mouse models.
For research use only. We do not sell to patients.
- Purity: 97.7%
- CAS No.: 479232-57-0
- Formula: C32H40N8O2S
- Molecular Weight:600.78
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Vasopressin Receptor Isoforms
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Biological Activity
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Avprla vasopressin receptor 300 nM (Ki) |
Oxytocin Receptor 180 nM (EC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
33 nM
Compound: 1
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Activity at human oxytocin receptor expressed in CHO cells by NFAT-luciferase gene reporter assay
Activity at human oxytocin receptor expressed in CHO cells by NFAT-luciferase gene reporter assay
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[PMID: 20104850] |
| CHO | EC50 |
850 nM
Compound: 1
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Activity at human vasopressin V2 receptor expressed in CHO cells by NFAT-luciferase gene reporter assay
Activity at human vasopressin V2 receptor expressed in CHO cells by NFAT-luciferase gene reporter assay
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[PMID: 20104850] |
Marble burying is based on the natural instinct of rodents to bury objects, commonly used in preclinical research to assess anxiety-like behavior in rodents[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 479232-57-0
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Appearance Solid
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Molecular Weight 600.78
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Formula C32H40N8O2S
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Color White to off-white
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SMILES
O=C(N1[C@H](C(N2CCN(C)CCC2)=S)CCC1)NCC3=CC=C(C(N4CC5=C(N(C)N=C5)NC6=CC=CC=C46)=O)C=C3C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)