SSR126768A free base
SSR126768A free base is an orally active antagonist for oxytocin receptor, with Ki of 0.44 nM. SSR126768A free base is a tocolytic agent, that antagonizes the Oxytocin (HY-17571)-induced intracellular Ca2+ increase and prostaglandin release in human uterine smooth muscle cells, inhibits thus the Oxytocin (HY-17571)-induced uterine contraction and delays parturition in pregnant rats in labor.
For research use only. We do not sell to patients.
- CAS No.: 785048-28-4
- Formula: C33H31Cl2N3O4
- Molecular Weight:604.52
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 785048-28-4
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Molecular Weight 604.52
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Formula C33H31Cl2N3O4
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SMILES
O=C(N(CC)CC1=CN=CC=C1)C2=CC=C(Cl)C([C@](C3=C(N4CC5=CC=C(OC)C=C5OC)C=CC(Cl)=C3)(C)C4=O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Serradeil-Le Gal C, et al., SSR126768A (4-chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, hydrochloride): a new selective and orally active oxytocin receptor antagonist for the prevention of preterm labor. J Pharmacol Exp Ther. 2004 Apr;309(1):414-24. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SSR126768A free base Related Classifications
HY-15018A Related Classifications
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