1. GPCR/G Protein
    Metabolic Enzyme/Protease
  2. Oxytocin Receptor
    Endogenous Metabolite
  3. Oxytocin acetate

Oxytocin acetate (Synonyms: α-Hypophamine acetate; Oxytocic hormone acetate)

Cat. No.: HY-17571A Purity: ≥99.0%
Handling Instructions

Oxytocin acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Oxytocin acetate Chemical Structure

Oxytocin acetate Chemical Structure

CAS No. : 6233-83-6

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10 mM * 1 mL in DMSO USD 99 In-stock
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50 mg USD 144 In-stock
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100 mg USD 240 In-stock
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500 mg USD 840 In-stock
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Customer Review

Based on 5 publication(s) in Google Scholar

Other Forms of Oxytocin acetate:

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Description

Oxytocin acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

During the LMA task, rat core body temperature are modestly decreased. Oxytocin acetate (subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3 mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60 min post injection, whereas 0.1 mg/kg slightly decreases temperature at the 30 min time point only[1].
Oxytocin acetate (0.1 mg/kg) engages in significantly more body sniffing and ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3 s), compared to those receiving vehicle (56.9±4.1 s)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Fifty-six male Lister-hooded rats (150–200 g)[1]
Dosage: 0.1 mg/kg-0.3 mg/kg
Administration: Subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose
Result: Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group.
Clinical Trial
Molecular Weight

1067.24

Formula

C₄₅H₇₀N₁₂O₁₄S₂

CAS No.
Sequence

Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge:Cys1-Cys6)

Sequence Shortening

CYIQNCPLG-NH2 (Disulfide bridge:Cys1-Cys6)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (46.85 mM; Need ultrasonic)

DMSO : ≥ 44 mg/mL (41.23 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9370 mL 4.6850 mL 9.3700 mL
5 mM 0.1874 mL 0.9370 mL 1.8740 mL
10 mM 0.0937 mL 0.4685 mL 0.9370 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Oxytocin acetate
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HY-17571A
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