(Phe2,Orn8)-Oxytocin
Based on 1 Customer Validation
(Phe2,Orn8)-Oxytocin is a selective V1 vasopressin agonist. (Phe2,Orn8)-Oxytocin induces a sustained contractility of rabbit epididymis with EC50 value of 280 nM.
For research use only. We do not sell to patients.
- Purity: 99.55%
- CAS No.: 2480-41-3
- Formula: C42H65N13O11S2
- Molecular Weight:992.18
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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GPCR/G Protein Compound Library
HY-L006
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Peptide Library
HY-L105
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Human Metabolite Library
HY-L123
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Highly Selective Activators Library
HY-L159
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MCE Bioactive Compound Library
HY-L001V
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Peptide Compound Library
HY-L105S
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High-Throughput Bioactive Compound Library
HY-L205
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Mass Spectrometry Human Metabolite Library
HY-L215
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Lactylation Compound Library
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All Vasopressin Receptor Isoforms
More
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO-K1 | EC50 |
>10000 nM
Compound: 7
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Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assay
Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assay
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[PMID: 21688787] |
| Flp-In-293 | EC50 |
25 nM
Compound: 7
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Agonist activity at recombinant human vasopressin V1b receptor expressed in Flp-In-293 cells by luciferase reporter gene assay
Agonist activity at recombinant human vasopressin V1b receptor expressed in Flp-In-293 cells by luciferase reporter gene assay
|
[PMID: 21688787] |
| HEK293 | EC50 |
0.12 nM
Compound: 7
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Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
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[PMID: 21688787] |
| HEK293 | EC50 |
0.27 nM
Compound: 7
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Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay
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[PMID: 21688787] |
| HEK293 | EC50 |
155 nM
Compound: 7
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Agonist activity at recombinant human vasopressin V2 receptor expressed in HEK293 cells by luciferase reporter gene assay
Agonist activity at recombinant human vasopressin V2 receptor expressed in HEK293 cells by luciferase reporter gene assay
|
[PMID: 21688787] |
Chemical Information
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CAS No. 2480-41-3
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Appearance Solid
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Molecular Weight 992.18
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Formula C42H65N13O11S2
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Color White to off-white
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Sequence
Cys-Phe-Ile-Gln-Asn-Cys-Pro-{Orn}-Gly-NH2 (Disulfide bridge: Cys1-Cys6)
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Sequence Shortening
CFIQNCP-{Orn}-G-NH2 (Disulfide bridge: Cys1-Cys6)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (50.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0079 mL | 5.0394 mL | 10.0788 mL | 25.1970 mL |
| 5 mM | 0.2016 mL | 1.0079 mL | 2.0158 mL | 5.0394 mL | |
| 10 mM | 0.1008 mL | 0.5039 mL | 1.0079 mL | 2.5197 mL | |
| 15 mM | 0.0672 mL | 0.3360 mL | 0.6719 mL | 1.6798 mL | |
| 20 mM | 0.0504 mL | 0.2520 mL | 0.5039 mL | 1.2599 mL | |
| 25 mM | 0.0403 mL | 0.2016 mL | 0.4032 mL | 1.0079 mL | |
| 30 mM | 0.0336 mL | 0.1680 mL | 0.3360 mL | 0.8399 mL | |
| 40 mM | 0.0252 mL | 0.1260 mL | 0.2520 mL | 0.6299 mL | |
| 50 mM | 0.0202 mL | 0.1008 mL | 0.2016 mL | 0.5039 mL |
(Phe2,Orn8)-Oxytocin Related Classifications
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