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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
77 Results for "
Aspergillus fumigatus
" in MedChemExpress (MCE) Product Catalog:
Products (77)
77 Results for "Aspergillus fumigatus" in MCE Product Catalog:
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Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. .
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Opelconazole (PC945), a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. Opelconazole is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B, with IC50s of 0.23 μM and 0.22 μM, respectively .
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1 Cited Publications
Cat. No.: HY-P2543
CAS No.: 150138-78-6
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Infection Zanthoxylum bungeanum Maxim. Monophenols Rutaceae Phenols Plants Disease Research Fields Zanthoxylum simulans Hance
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Cat. No.: HY-W007626
CAS No.: 7311-34-4
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APX2039 is a brain-penetrant and orally active Gwt1 protein inhibitor. APX2039 inhibits an early step in fungal glycosylphosphatidylinositol anchor biosynthesis. APX2039 can be used for the research of cryptococcal meningitis and invasive mycosis caused by Talaromyces marneffei .
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T-2307 is an antifungal agent with blood-brain barrier penetration. T-2307 exhibits broad-spectrum antifungal activity against Candida species, including echinocandin-resistant strains, Cryptococcus neoformans, Cryptococcus gattii, and some Aspergillus species. T-2307 selectively targets fungal mitochondrial respiratory chain complexes III and IV, causing collapse of the fungal mitochondrial membrane potential and exerting fungicidal or fungistatic effects. T-2307 can be used in research related to fungal infections such as invasive candidiasis, cryptococcosis, and aspergillosis .
Cat. No.: HY-N2198
CAS No.: 22136-74-9
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Flavonoids Guttiferae Phenols Polyphenols Plants Garcinia subelliptica Disease Research Fields Biflavones Cancer
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Cat. No.: HY-W068682
CAS No.: 528-71-2
Synonyms: Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin
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Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
1-Hydroxyphenazine (Hemipyocyanine; 1-Phenazinol; Hemi-pyocyanin) is an inhibitor for α-Amylase with an IC50 of 3.1 μg/mL . 1-Hydroxyphenazine exhibits anticancer and anti-inflammatory activity against cells A549, 1321N1 and RAW264.7, antifungal and antibacterial activity against strains Candida albicans, Aspergillus fumigatus, Escherichia coli and Xanthomonas campestris .
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Cat. No.: HY-P2274
CAS No.: 243975-37-3
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Cat. No.: HY-136153
CAS No.: 136135-57-4
Amphotericin X1 is an 13-O-methyl derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, C.parapsilosis 937A, Cryptococcus neoformans 451, Aspergillus niger 57A and A.fumigatus with MIC values of 1 μg/mL, 8 μg/mL, 1 μg/mL, 2 μg/mL and 2 μg/mL, respectively .
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Cat. No.: HY-170616
CAS No.: 3062848-75-0
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JH-FK-08 is an inhibitor for the serine/threonine-specific phosphatase calcineurin. JH-FK-08 exhibits antifungal activity that inhibits C. neoformans with MIC80 of 0.8 µg/mL. JH-FK-08 exhibits immunosuppressive activity and inhibits the IL-2 expression with an IC50 of 42.6 nM. JH-FK-08 exhibits anti-infectious activity in mouse models .
Cat. No.: HY-W782599
CAS No.: 93236-67-0
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Zanthoxylum bungeanum Maxim. Monophenols Rutaceae Phenols Plants Zanthoxylum simulans Hance
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Cat. No.: HY-B0751R
CAS No.: 23110-15-8
Synonyms: Amebacilin (Standard); NSC9168 (Standard)
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Cat. No.: HY-W077257
CAS No.: 6548-09-0
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
