(E,Z)-Platanoside
(E,Z)-Platanoside is a flavonoid glycoside. (E,Z)-Platanoside is a potent and highly selective MRSA inhibitor; it exhibits low activity against other tested strains, including Gram-negative bacteria, intracellular Mycobacterium intracellulare, Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. (E,Z)-Platanoside can be used in research on MRSA infections.
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- CAS No.: 1197343-17-1
- Formule: C39H32O14
- Masse moléculaire:724.66
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
11.9 μM
Compound: 11
|
Cytotoxicity against human HeLa cells assessed as growth inhibition by sulforhodamine B assay
Cytotoxicity against human HeLa cells assessed as growth inhibition by sulforhodamine B assay
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[PMID: 26722868] |
(E,Z)-Platanoside (0-100 μg/mL) exhibits bacteriostatic activity against MRSA and S. aureus (IC50 = 0.8 μg/mL for MRSA; IC50 = 1.6 μg/mL for S. aureus)[1].
(E,Z)-Platanoside (0-100 μg/mL) shows no cytotoxicity against Vero cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1197343-17-1
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Masse moléculaire 724.66
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Formule C39H32O14
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SMILES
O=C(C(O[C@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)OC(/C=C\C2=CC=C(C=C2)O)=O)OC(/C=C/C3=CC=C(C=C3)O)=O)=C(C4=CC=C(C=C4)O)OC5=CC(O)=C6)C5=C6O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)