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Argifin 

Cat. No.: HY-P2274
Handling Instructions

Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Argifin Chemical Structure

Argifin Chemical Structure

CAS No. : 243975-37-3

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Description

Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].

IC50 & Target

IC50: 0.025 μM (SmChiA), 6.4 μM (SmChiB), 1.1 μM (Aspergillus fumigatus chitinase B1), 4.5 μM (human chitotriosidase)[1]

In Vitro

Argifin inhibits L. cuprina chitinase with IC50 values of 3.7 μM at 37 ºC and 0.10 μM at 20 ºC[1].

In Vivo

Argifin has the ability to inhibit L. cuprina molting[1].

Molecular Weight

675.69

Formula

C₂₉H₄₁N₉O₁₀

CAS No.

243975-37-3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

ArgifinParasitechitinaseSmChiASmChiBchitotriosidaseInhibitorinhibitorinhibit

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Argifin
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