243975-37-3
243975-37-3
Chemical Structure
Argifin
- CAS No.: 243975-37-3
- Formula:C29H41N9O10
- Molecular Weight:675.69
InChIKey: UHBHXSDKGLPPGO-HTDHLNIYSA-N
SMILES: CN(C([C@@H](NC([C@H](NC1=O)C)=O)CCCNC(NC(NC)=O)=N)=O)[C@H](C(N[C@@H](CC(N[C@@H](C1)C(O)=O)=O)C(O)=O)=O)CC2=CC=CC=C2
Biological Activity: Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Argifin | 99.90% | Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively. | ||||||||||||||||||||
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Argifin (Standard) | ≥98% | Argifin (Standard) is the analytical standard of Argifin. This product is intended for research and analytical applications. Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.64
HY-16143Cilengitide TFA -
Similarity Score 0.64
HY-16141RCilengitide (Standard) -
Similarity Score 0.62
HY-P4907RGD Negative Control -
Similarity Score 0.61
HY-111413c(phg-isoDGR-(NMe)k) -
Similarity Score 0.61
HY-P2306Cyclo(Arg-Ala-Asp-D-Phe-Cys) -
Similarity Score 0.61
HY-P1613ACyclo(Arg-Gly-Asp-D-Phe-Val) TFA -
Similarity Score 0.61
HY-P5021Cyclo(Arg-Gly-Asp-(D-Phe)-Glu) -
Similarity Score 0.60
HY-P1613Cyclo(Arg-Gly-Asp-D-Phe-Val) -
Similarity Score 0.60
HY-P0031Cyclo(RADfK) -
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