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Olorofim (Synonyms: F901318)

Cat. No.: HY-104029
Handling Instructions

Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp..

For research use only. We do not sell to patients.

Olorofim Chemical Structure

Olorofim Chemical Structure

CAS No. : 1928707-56-5

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Description

Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp.[1].

IC50 & Target

Dihydroorotate dehydrogenase[1]

Molecular Weight

498.55

Formula

C₂₈H₂₇FN₆O₂

CAS No.

1928707-56-5

SMILES

O=C(NC1=CC=C(N2CCN(C3=NC=C(F)C=N3)CC2)C=C1)C(C4=C(C5=CC=CC=C5)C=C(C)N4C)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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