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Cat. No.: HY-153624

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Antifungal agent 59

Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety.

For research use only. We do not sell to patients.

CAS No.: 2422019-96-1
Formula: C₁₈H₁₅BrF₂N₂Se
Molecular Weight:456.19

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Antifungal agent 59 Chemical Structure

CAS No.: 2422019-96-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety^[1].

In Vitro

Antifungal agent 59 (compound A23) shows in vitro antifungal activity with MIC values of 0.02 μg/mL (Candida albicans), 0.01 μg/mL (Candida albicans), 0.25 μg/mL (Candida zeylanoides), 0.25 μg/mL (Cryptococcus neoformans), 0.06 μg/mL (Candida kruseii), 1 μg/mL (Candida glabrata), 0.02 μg/mL (Candida parapsilosis), and 1 μg/mL (Aspergillus fumigatus), respectively^[1].
Antifungal agent 59 (0.02 μg/mL ;48 h) potently kills Candida albicans^[1].
Antifungal agent 59 (1-16 μg/mL) shows hemolytic activity against rabbit red blood cells, with 93.47% hemolysis at concentrations of 8 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2422019-96-1
Molecular Weight 456.19
Formula C₁₈H₁₅BrF₂N₂Se
SMILES

FC1=CC=C(C([Se]CC2=CC=CC=C2Br)CN3C=CN=C3)C(F)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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