1. Anti-infection
  2. Fungal
  3. Antifungal agent 59

Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety.

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Antifungal agent 59 Chemical Structure

Antifungal agent 59 Chemical Structure

CAS No. : 2422019-96-1

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Description

Antifungal agent 59 is an antifungal agent, with MIC values of 0.01-1 μg/mL. Antifungal agent 59 prevents the formation of fungi biofilms, but also has safety[1].

In Vitro

Antifungal agent 59 (compound A23) shows in vitro antifungal activity with MIC values of 0.02 μg/mL (Candida albicans), 0.01 μg/mL (Candida albicans), 0.25 μg/mL (Candida zeylanoides), 0.25 μg/mL (Cryptococcus neoformans), 0.06 μg/mL (Candida kruseii), 1 μg/mL (Candida glabrata), 0.02 μg/mL (Candida parapsilosis), and 1 μg/mL (Aspergillus fumigatus), respectively[1].
Antifungal agent 59 (0.02 μg/mL ;48 h) potently kills Candida albicans[1].
Antifungal agent 59 (1-16 μg/mL) shows hemolytic activity against rabbit red blood cells, with 93.47% hemolysis at concentrations of 8 μg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

456.19

Formula

C18H15BrF2N2Se

CAS No.
SMILES

FC1=CC=C(C([Se]CC2=CC=CC=C2Br)CN3C=CN=C3)C(F)=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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References
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Antifungal agent 59 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antifungal agent 59
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HY-153624
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