Search Result
Results for "
Glucuronide
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
54
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-N12469
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Others
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Others
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Gypsogenin 3-O-glucuronide is a glucuronide that can be isolated from Gypsophila. Gypsogenin 3-O-glucuronide has cytotoxic effect on THP-1 cells .
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- HY-137339
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Others
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Others
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Amitriptyline N-β-D-glucuronide is an ammonium glucuronide and an urinary excretion metabolite of amitriptyline .
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- HY-148225
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Others
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Cancer
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Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer .
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- HY-126423
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Isorhamnetin 3-O-Glucuronide
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Others
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Cancer
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Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase .
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- HY-137321
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Estriol 3-β-D-Glucuronide sodium salt
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Endogenous Metabolite
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Metabolic Disease
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Estriol 3-glucuronide (Estriol 3-β-D-Glucuronide) sodium salt is a metabolite of Estriol. Estriol 3-glucuronide sodium salt competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide (4Mu-GlcU). Estriol 3-glucuronide sodium salt is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc) .
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- HY-113157
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Drug Metabolite
Endogenous Metabolite
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Others
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Estrone 3-glucuronide is deuterium labeled Estrone 3-glucuronide. Estrone 3-glucuronide, the dominant metabolite of estradiol, is determined to be the urinary marker for prediction of the fertile window .
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- HY-W778608
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Quercetin 7-O-β-Glucuronide
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Drug Metabolite
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Inflammation/Immunology
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Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a metabolite of Quercetin (HY-18085), can be isolated from Madagascarian Uncarina species. Quercetin 7-glucuronide can inhibit LDL oxidation .
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- HY-135955
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Thyroxine acyl-β-D-Glucuronide
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Endogenous Metabolite
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Metabolic Disease
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Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide), an endogenous metabolite, is the acyl glucuronide formation of thyroxine (T4) .
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- HY-137301S
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- HY-143911S
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- HY-143927S
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- HY-143957S
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- HY-144201S
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- HY-151706S
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- HY-135391
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Ezetimibe Glucuronide; Ezetimibe β-D-Glucuronide
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Drug Metabolite
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Metabolic Disease
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Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity . Ezetimibe is a potent cholesterol absorption inhibitor .
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- HY-125370S
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- HY-154762S
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- HY-113093S
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Isotope-Labeled Compounds
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Others
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Ethyl glucuronide-d5is the deuterium labeledEthyl glucuronide(HY-113093) . Ethyl glucuronide is an endogenous metabolite .
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- HY-151027S
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- HY-132618S
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- HY-N11429
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Others
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Metabolic Disease
Cancer
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Glycochenodeoxycholic acid 3-glucuronide is a type of steroid glucuronide and a plasma metabolite that can be used for biomarker research in diabetes and hepatocellular carcinoma (HCC) .
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- HY-113104S
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- HY-144247S
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- HY-W121901
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(S)-Naproxen-β-D-Glucuronide
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COX
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Inflammation/Immunology
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Naproxen glucuronide ((S)-Naproxen-β-D-glucuronide) is a non-selective COX inhibitor. Naproxen glucuronide, a metabolite of naproxen, is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same as ibuprofen) that relieves pain, fever, swelling, and stiffness .
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- HY-N7176
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Kaempferol-3-Glucuronide; Kaempferol-3-O-Glucuronide
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Interleukin Related
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Inflammation/Immunology
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Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide), one conjugated kaempferol metabolite, has anti-inflammatory effect. Kaempferol 3-O-β-D-glucuronide significantly inhibits various pro-inflammatory mediators like IL-1β, NO, PGE2, and LTB4. Kaempferol 3-O-β-D-glucuronide upregulates the secretion of anti-inflammatory cytokine IL-10 .
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- HY-141914S
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- HY-143929S
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- HY-135581
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Estrogen Receptor/ERR
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Endocrinology
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Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
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- HY-135582
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Estrogen Receptor/ERR
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Endocrinology
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Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
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- HY-113169
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- HY-135391S
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Ezetimibe Glucuronide-d4; Ezetimibe β-D-Glucuronide-d4
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Drug Metabolite
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Metabolic Disease
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Ezetimibe phenoxy glucuronide-d4 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
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- HY-135582S
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Estrogen Receptor/ERR
Isotope-Labeled Compounds
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Endocrinology
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Raloxifene 4'-glucuronide-d4 is deuterated labeled Raloxifene 4'-glucuronide (HY-135582). Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
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- HY-144166S
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- HY-111587
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Others
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Cardiovascular Disease
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Ifenprodil glucuronide is a derivative of Ifenprodil. Ifenprodil is a vasodilator and an inhibitor of platelet aggregation, and Ifenprodil glucuronide has no effect on platelet aggregation and arterial contraction .
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- HY-W016034
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p-Acetamidophenyl β-D-Glucuronide sodium salt; p-AAPG sodium salt
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Others
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Infection
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Acetaminophen glucuronide is a safe and effective
antipyretic analgesic. Acetaminophen glucuronide is potentially toxic to liver
and kidney .
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- HY-137301
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Drug Metabolite
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Cancer
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Mycophenolic acid glucuronide is a metabolite of the immunosuppressant mycophenolic acid (MPA). Mycophenolic acid glucuronide shows anti-tumor activity and can be used in adenocarcinoma research .
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- HY-123742
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Others
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Metabolic Disease
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Estradiol 3-sulfate 17-glucuronide potassium is metabolite of estradiol. Estradiol 3-sulfate 17-glucuronide potassium inhibits multidrug resistance protein (MRP) mediated 17β -Estradiol 17-(β -D-Glucuronide) transport with a Ki of 22 μM .
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- HY-113018A
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(S)-Ibuprofen Glucuronide
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Others
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Inflammation/Immunology
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(S)-Ibuprofen acyl-β-D-glucuronide ((S)-Ibuprofen glucuronide) is a compound used to study the metabolism and pharmacokinetics of S-ibuprofen, a non-steroidal anti-inflammatory drug. (S)-Ibuprofen acyl-β-D-glucuronide is an acylglucuronic acid metabolite produced by S-ibuprofen in the liver .
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- HY-113093
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- HY-N12394
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Others
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Inflammation/Immunology
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Norwogonin-8-O-glucuronide is a glucuronide that can be isolated from Scutellaria indica. Norwogonin-8-O-glucuronide has anti-inflammatory activity .
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- HY-135581S1
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Estrogen Receptor/ERR
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Endocrinology
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Raloxifene 6-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression[1][2][3].
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- HY-135582S1
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Estrogen Receptor/ERR
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Endocrinology
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Raloxifene 4'-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 4'-glucuronide. Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. [1][2]. Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression[3].
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- HY-N12028
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Others
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Others
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Acacetin 7-O-glucuronide is a glucuronide isolated from the methanolic leaf extract of Acacetin. Acacetin 7-O-glucuronide has potential applications in the development of nutraceuticals and pharmaceutical formulations .
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- HY-129889
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Febuxostat acyl-β-D-Glucuronide
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Drug Metabolite
Xanthine Oxidase
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Metabolic Disease
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Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor .
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- HY-137967
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Genistein 7-O-Glucuronide
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Others
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Endocrinology
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Genistein 7-β-D-Glucuronide is a natural product. Genistein 7-β-D-Glucuronide inhibits tubulogenesis and endothelial migration[1].
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- HY-135391S1
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Drug Metabolite
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Others
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Ezetimibe phenoxy glucuronide-d4-1 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2][3].
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- HY-135956
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- HY-W588241
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Others
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Others
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Serotonin glucuronide is the product of Serotonin glucuronidation .
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- HY-N2066
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Naringenin 7-O-β-D-Glucuronide
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Others
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Inflammation/Immunology
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Naringenin 7-O-glucuronide (Naringenin 7-O-β-D-glucuronide) is a bergamot juice metabolite that can be used in the study of inflammation .
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- HY-136307S
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Parasite
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Infection
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Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum[1].
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- HY-W416250
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Others
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Cardiovascular Disease
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p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD) .
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- HY-W016034S
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p-Acetamidophenyl β-D-Glucuronide-d3 sodium salt; p-AAPG-d3 sodium salt
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Isotope-Labeled Compounds
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Others
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Acetaminophen glucuronide-d3 sodium salt is the deuterium labeled Acetaminophen glucuronide sodium salt.
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- HY-137426A
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- HY-143915S
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- HY-N11026
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Others
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Others
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22-Beta-Acetoxyglycyrrhizin is a triterpene glucuronide that can be isolated from the roots of Glycyrrhiza .
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- HY-N2481
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Oroxyloside; Oroxylin A-7-O-β-D-Glucuronide
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Prolyl Endopeptidase (PREP)
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Neurological Disease
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Oroxylin A-7-O-glucuronide (Oroxyloside; Oroxylin A-7-O-β-D-glucuronide) is a flavonoid glucuronide isolated from the dried root of Scutellaria baicalensis, with prolyl oligopeptidase (POP) inhibitory activity .
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- HY-113018S
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- HY-N1454
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Apigenin 7-O-Glucuronide
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Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively.
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- HY-155792
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Others
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Others
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Troglitazone glucuronide (Compound M2) is an initial metabolite of troglitazone in the liver .
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- HY-N8841
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Others
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Others
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Daidzein-7-O-glucuronide (compound 3) is a main metabolite of daidzein. Daidzein-7-O-glucuronide has oral activity .
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- HY-W040047
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Endogenous Metabolite
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Endocrinology
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Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species .
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- HY-G0020S1
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- HY-W588194S
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- HY-N7390
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- HY-138795
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Others
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Cancer
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Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer .
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- HY-W008917S1
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- HY-141942S
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- HY-143953S
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- HY-160078
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Others
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Metabolic Disease
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Deferiprone O-β-D-glucuronide is a novel orally active iron chelator. Deferiprone O-β-D-glucuronide shows the capability of reducing the iron burden in patients with β-thalassemia .
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- HY-13930
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Quercetin 3-O-Glucuronide; Quercetin 3-Glucuronide
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Endogenous Metabolite
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Cancer
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Miquelianin (Quercetin 3-O-glucuronide) is a metabolite of quercetin and a type of natural flavonoid. Miquelianin is also a CBR1 inhibitor.
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- HY-122317
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Drug Metabolite
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Others
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Menthol glucuronide, a metabolite of Menthol (HY-N1369), is a plasma and urine biomarker of acute Menthol inhalation .
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- HY-132480S
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- HY-118774S
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- HY-142598S
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- HY-142266S
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- HY-113083
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APAP-glu
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Drug Metabolite
Endogenous Metabolite
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Others
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Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005) . Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor .
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- HY-111812
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- HY-W353102
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Endogenous Metabolite
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Metabolic Disease
Endocrinology
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Estradiol 17-(β-D-Glucuronide), a metabolite of estrogen, is well known to cause intrahepatic cholestasis in humans. Estradiol 17-(β-D-Glucuronide) is a high-affinity substrate for oatp organic anion transporter .
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- HY-137522S
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3'-Azido-3'-deoxythymidine β-D-Glucuronide-d3 sodium
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Isotope-Labeled Compounds
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Others
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Zidovudine O-β-D-glucuronide-d3 (sodium) (3'-Azido-3'-deoxythymidine β-D-glucuronide-d3 (sodium)) is a deuterium labeled Zidovudine O-β-D-glucuronide (sodium) (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .
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- HY-137522A
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3'-Azido-3'-deoxythymidine β-D-Glucuronide
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Drug Metabolite
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Others
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .
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- HY-N12025
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Others
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Others
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Eriodictyol 7-O-glucuronide is a flavonoid isolated from Cosmos sulphureus .
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- HY-141903S
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- HY-N7755
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Estrogen Receptor/ERR
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Cancer
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Estradiol 3-(β-D-Glucuronide) sodium is the glucuronic acid derivative of estradiol (HY-B0141). Estradiol 3-(β-D-Glucuronide) sodium is radiolabeled for use in tumor imaging and biodistribution studies .
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- HY-137083
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UGT1A4
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UGT
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Metabolic Disease
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Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation .
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- HY-137083A
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UGT1A4 chloride
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Others
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Neurological Disease
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Trifluoperazine N-glucuronide (UGT1A4) chloride is a metabolite of the antipsychotic agent trifluoperazine. Trifluoperazine N-glucuronide (UGT1A4) chloridecatalyzes the imipramine and trifluoperazine Nglucuronide formation .
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- HY-122813S1
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- HY-44221
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ADC Linker
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Cancer
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MAC glucuronide linker-1 is a claevable ADC linker for antibody-agent-conjugations (ADCs) .
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- HY-D0935
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4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
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- HY-145736
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Drug-Linker Conjugates for ADC
Apoptosis
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Cancer
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β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 has antitumor activity .
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- HY-137912
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Others
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Endocrinology
Cancer
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trans-Resveratrol-3-O-β-D-Glucuronide is an active metabolite of trans-resveratrol. trans-Resveratrol-3-O-β-D-Glucuronide reduces the proliferation of several intestinal cancer cell line. trans-Resveratrol-3-O-β-D-Glucuronide increases pyruvate production in livers .
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- HY-154772S
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- HY-N2376
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Others
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Others
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Chrysin-7-O-glucuronide is a flavonoid extracted from Scutellaria baicalensis, with antioxidant activity .
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- HY-142581S
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- HY-W040047S
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- HY-156180
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Drug Metabolite
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Neurological Disease
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DDC 3′-O-β-D glucuronide (compound 5) is a drug metabolite that can prevent the fibrillization and oligomerization of Aβ42. DDC 3′-O-β-D glucuronide has potential for the research of Alzheimer's disease .
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- HY-44222
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ADC Linker
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Cancer
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MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-113245
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Endogenous Metabolite
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Others
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3-Indolyl-β-D-glucuronide, a chromogenic substrate for β-D-glucuronidase, employs in the detection and enumeration of E. coli, yielding a blue precipitate upon cleavage. 3-Indolyl-β-D-glucuronide in? patients' plasma act as a new indicator of renal failure .
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- HY-N6851
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Glycyrrhetic acid 3-O-mono-β-D-Glucuronide; 3-monoglucuronyl-glycyrrhetinic acid
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Others
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Inflammation/Immunology
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Glycyrrhetic acid 3-O-β-D-glucuronide, isolated from glycyrrhiza, is an important derivative of glycyrrhizin (GL) with an anti -allergic activity . Glycyrrhetic acid 3-O-β-D-glucuronide (GAMG) shows that β-glucuronidases (β-GUS) are key GAMG-producing enzymes, displaying a high potential to convert GL directly into GAMG .Glycyrrhetic acid 3-O-β-D-glucuronide is valuable as a sweetener.
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- HY-137522
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3'-Azido-3'-deoxythymidine β-D-Glucuronide sodium
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Drug Metabolite
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Others
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection . Zidovudine O-β-D-glucuronide (sodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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- HY-128943
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Drug-Linker Conjugates for ADC
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Cancer
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MAC glucuronide phenol-linked SN-38 is a pH-susceptible lactone MAC glucuronide phenol-linked SN-38 (DNA topoisomerase I inhibitor) agent linker. MAC glucuronide phenol-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 113 and 67 ng/mL, respectively.Albumin-coupled MAC glucosidol-linked SN-38 shows good stability in mouse plasma .
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- HY-145736A
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Drug-Linker Conjugates for ADC
Apoptosis
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Cancer
|
β-Glucuronide-dPBD-PEG5-NH2 TFA is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD.β-glucuronide-linkage as a cleavable linker. β-Glucuronide-dPBD-PEG5-NH2 TFA, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 TFA can induce apoptosis and arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 TFA has antitumor activity .
|
-
- HY-137083S
-
UGT1A4-d3
|
Isotope-Labeled Compounds
|
Metabolic Disease
|
Trifluoperazine N-glucuronide-d3 is deuterium labeled Trifluoperazine N-Glucuronide. Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1].
|
-
- HY-D0935A
-
MUG
|
Fluorescent Dye
|
Others
|
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
|
-
- HY-137833
-
Naphthol AS-BI β-D-Glucuronide
|
Biochemical Assay Reagents
|
Others
|
Naphthol AS-BI β-D-Glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-141945S
-
|
Isotope-Labeled Compounds
|
Others
|
Taurochenodeoxycholic acid-3-o-glucuronide-d4 (disodium) is the deuterium labeled Taurochenodeoxycholic acid-3-o-glucuronide[1].
|
-
- HY-137912S1
-
-
- HY-142119S
-
-
- HY-120201S
-
-
- HY-137188
-
-
- HY-N8578
-
|
Others
|
Others
|
Luteolin 7,3′-di-O-glucuronide is a flavonoid compound of the luteolin family .
|
-
- HY-W039892
-
pNPG_1
|
Others
|
Others
|
4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-nitrophenol 4-Nitrophenyl β-D-glucuronide is a chromogenic compound and is the chromogenic substrate for β-glucuronidase .
|
-
- HY-136344
-
|
Drug Metabolite
|
Others
|
Simvastatin Acyl-β-D-glucuronide is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM .
|
-
- HY-137963
-
-
- HY-N6879
-
|
Others
|
Metabolic Disease
|
DiosMetin 7-O-β-D-Glucuronide is an antioxidant constituent in the fruits of Luffa cylindrical .
|
-
- HY-W145687
-
Diosgenin-3-O-Β-D-Glucuronide
|
Biochemical Assay Reagents
|
Others
|
Diosgenin-3-O-β-D-sodium glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-150985S
-
|
Isotope-Labeled Compounds
|
Others
|
2,2'-Dichloro bisphenol a mono-D-glucuronide-d12 is the deuterium labeled 2,2'-Dichloro bisphenol a mono-D-glucuronide[1].
|
-
- HY-132723S
-
-
- HY-132723AS
-
-
- HY-118774
-
-
- HY-135245
-
SCH 488128; Ezetimibe hydroxy β-D-Glucuronide
|
Drug Metabolite
|
Cardiovascular Disease
|
Ezetimibe hydroxy glucuronide (SCH 488128) is a trace metabolite detected in dog and human plasma samples after oral administration of Ezetimibe (HY-17376) .
|
-
- HY-129987
-
-
- HY-D1460
-
|
Bacterial
|
Infection
|
Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies .
|
-
- HY-137816
-
|
Others
|
Others
|
6-Chloro-3-indolyl-β-D-glucuronide cyclohexylammonium salt is a chromogenic substrate for β-glucuronidase. 6-Chloro-3-indolyl-β-D-glucuronide cyclohexylammonium salt produces a salmon colored precipitate upon cleavage .
|
-
- HY-128942
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a stabilized lactone MAC glucuronide α-hydroxy lactone-linked SN-38 agent linker. MAC glucuronide α-hydroxy lactone-linked SN-38 is cytotoxic across L540cy cells and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively .
|
-
- HY-153642
-
-
- HY-136329
-
|
ADC Linker
|
Cancer
|
β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-N10647
-
|
Others
|
Inflammation/Immunology
|
Isoscutellarein 8-O-β-D-glucuronide is a flavonoid antioxidant, can be isolated from Theobroma grandiflorum seeds .
|
-
- HY-142279S
-
-
- HY-N1463
-
Luteolin 7-Glucuronide
|
|
|
Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively .
|
-
- HY-W145619
-
|
Biochemical Assay Reagents
|
Others
|
4-Nitrophenyl α-D-Glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W154341
-
|
Biochemical Assay Reagents
|
Others
|
3-Indolyl-β-D-glucuronide cyclohexanamine is the glucose component of X-Gluc staining buffer. 3-Indolyl-β-D-glucuronide cyclohexanamine can be used to detect gene expression. The active ingredient of the stain, β-Glucuronidase (GUS), reacts with the enzyme, causing the target gene to appear blue-purple in tissues or cells, so that the expression level and tissue distribution of the gene can be visually observed .
|
-
- HY-126373
-
SN-38G
|
Drug Metabolite
|
Cancer
|
SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .
|
-
- HY-N4099
-
|
Others
|
Inflammation/Immunology
|
Luteolin-3-O-beta-D-glucuronide is a luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 3'-position.
|
-
- HY-126848
-
-
- HY-N12588
-
|
Others
|
Others
|
Quercetin 3-O-β-D-glucuronide-6″-methyl ester is a flavonoid isolated from Atraphaxis spinosa L .
|
-
- HY-135588
-
|
Drug Metabolite
|
Metabolic Disease
|
Raloxifene 6,4'-Bis-β-D-glucuronide (compound IV) is a metabolite of Raloxifene. Raloxifene is a selective estrogen receptor antagonist for the prevention of osteoporosis .
|
-
- HY-N7035
-
Wogonoside methyl ester
|
Others
|
Metabolic Disease
|
Wogonin 7-O-beta-D-glucuronide methyl ester is a natural compound isolated from Huanglian Jiedutang .
|
-
- HY-126373S1
-
SN-38G-13C6
|
Isotope-Labeled Compounds
|
Others
|
SN-38 glucuronide- 13C6 is the 13C labeled SN-38 glucuronide (HY-126373) . SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .
|
-
- HY-N10799
-
|
Others
|
Others
|
Oroxylin A 7-O-β-D-glucuronide methyl ester is a nature product that could be isolated form the roots of Scutellaria baicalensis Georgi .
|
-
- HY-113105
-
Estriol 16-glucosiduronate
|
Endogenous Metabolite
|
Others
|
Estriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy .
|
-
- HY-129993
-
-
- HY-118634S
-
-
- HY-N8029
-
|
Others
|
Others
|
6-Hydroxyapigenin 6-O-β-D-glucoside-7-O-β-D-glucuronide (compound 8) is a kind of flavonoid. 6-Hydroxyapigenin 6-O-β-D-glucoside-7-O-β-D-glucuronide can be isolated from the water extract of Carthamus tinctorius .
|
-
- HY-118634
-
R-4G
|
FATP
|
Metabolic Disease
|
Trans-Resveratrol-4'-O-D-Glucuronide (R-4G) is a metabolite of resveratrol with anti-fat accumulation property, and can be used for metabolic research .
|
-
- HY-155313
-
|
Drug-Linker Conjugates for ADC
|
Cancer
|
β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE (compound 20) is auristatins-glucuronide conjugate. Antitumor agent-122 shows in vitro antiproliferative activities against β-glucuronidase pretreated and untreated cancer cells with an IC50 value of 5.7 nM - 9.7 nM. Antitumor agent-122 shows potent antitumor efficacy in HCT-116 xenograft mouse model without inducing side effects .
|
-
- HY-154774S
-
-
- HY-160251
-
(3'R,5k'S)-trans-3'-Hydroxycotinine Glucuronide
|
Others
|
Others
|
3-HC-Gluc ((3’R,5k’s)-trans-3’ -Hydroxycotinine glucuronide) The trans-structure of 3-HC, the main metabolite of nicotine .
|
-
- HY-N12299
-
Quercetin 3-O-β-D-Glucuronide butyl ester
|
Others
|
Cancer
|
Parthenosin (Quercetin 3-O-β-D-glucuronide butyl ester) is a flavonoid, that can be isolated from the aerial parts of Calligoum polygonoides. Parthenosin shows cytotoxic activity against HepG2 and MCF-7 cell lines with IC50 values of 60.46 and 61.4 μg/mL, respectively .
|
-
- HY-N1439
-
Gypsogenin-3-O-(6-O-methyl)-glucoside
|
|
|
Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila .
|
-
- HY-148044
-
|
Bacterial
|
Infection
|
UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes .
|
-
- HY-157129
-
|
AMPK
|
Cardiovascular Disease
|
AMPK-α1β1γ1 activator 1 (M1) is an acyl glucuronide metabolite of Indole-3-carboxylic Acid-based AMPK activator. AMPK-α1β1γ1 activator 1 can selectively activated human β1 isoforms with an EC50 value of 38.1nM. AMPK-α1β1γ1 activator 1 can direct binding with human AMPK α1β1γ1 isoform. AMPK-α1β1γ1 activator 1 can be used for the research of diabetic nephropathy .
|
-
- HY-148379
-
|
Others
|
Others
|
Tetrahydrocortisone acetate is a intermediate product for production of tetrahydrocortisone 3-glucuronide .
|
-
- HY-148378
-
|
Others
|
Others
|
5β-Dihydrocortisone acetate can be used for the synthesis of tetrahydrocortisone 3-glucuronide .
|
-
- HY-135591
-
|
Others
|
Others
|
Methyl Raloxifene 4'-(2,3,4-Tri-O-acetyl-β-D-glycopyranuronate) is an analogue of Raloxifene 4'-glucuronide.
|
-
- HY-135587
-
|
Others
|
Others
|
4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene (Compound 4) is a reaction product of Raloxifene with tertbutyldimethylsilyl chloride. 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene is used to synthesize Raloxifene 6-glucuronide .
|
-
- HY-50175
-
-
- HY-50175A
-
-
- HY-125678S
-
-
- HY-W777199
-
|
Drug Metabolite
|
Others
|
Tianeptine metabolite MC5 sodium salt is a major active metabolite of tianeptine. Tianeptine and MC5 metabolite are eliminated with bile as glucuronide and glutamine conjugates .
|
-
- HY-N0197
-
Baicalin
Maximum Cited Publications
17 Publications Verification
Baicalein 7-O-β-D-Glucuronide
|
NF-κB
Autophagy
HIV
|
Inflammation/Immunology
Cancer
|
Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB .
|
-
- HY-D1707
-
|
Fluorescent Dye
|
Others
|
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .
|
-
- HY-113972A
-
|
Others
|
Inflammation/Immunology
|
(E/Z)-Methyl mycophenolate is a racemic compound of (Z)-Methyl mycophenolate and (E)-Methyl mycophenolate isomers. Methyl mycophenolate is a methyl ester of mycophenolic acid. Methyl mycophenolate can be used to synthesize mycophenolic acid β-D-glucuronide and phenolic glycosides .
|
-
- HY-113095
-
|
Drug Metabolite
Endogenous Metabolite
|
Others
|
γ-CEHC is a γ-tocopherol (HY-N7148) metabolite. γ-CEHC is mainly excreted into the urine rather than into the bile. γ-CEHC is present in conjugated form in human urine, mainly as glucuronide .
|
-
- HY-B0947
-
|
Bacterial
|
Infection
|
Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) .
|
-
- HY-W097018
-
|
Biochemical Assay Reagents
|
Others
|
Iomeprol intermediate-1 (compound 5) is an iodinated polysaccharide compound used in the synthesis of contrast agents. The amino group of Iomeprol intermediate-1 can be coupled to the carboxyl group of the D-glucuronide subunit of non-animal stable hyaluronic acid (NASHA), providing a water-soluble, radiopaque moiety .
|
-
- HY-B0947S1
-
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
Sulfanitran- 13C6 is the 13C labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
|
-
- HY-137869
-
5-Bromo-6-chloro-3-indolyl β-D-Glucuronide cyclohexylammonium
|
Biochemical Assay Reagents
|
Others
|
Magenta-β-D-GlcA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
Cat. No. |
Product Name |
Type |
-
- HY-D0935A
-
MUG
|
Chromogenic Substrates
|
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
|
-
- HY-D1460
-
|
Fluorescent Dyes/Probes
|
Fluorescein Di-β-D-Glucuronide, a fluorescent probe, can be utilized to non-invasively image the intestinal bacterial β-glucuronidase activity in nude mice. Fluorescein Di-β-D-Glucuronide-based imaging reveals the in vitro and in vivo activity of intestinal bacterial β-glucuronidase, which would facilitate pharmacodynamic studies of specific bacterial β-glucuronidase inhibitors in animal studies .
|
-
- HY-D1707
-
|
Fluorescent Dyes/Probes
|
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm) .
|
Cat. No. |
Product Name |
Type |
-
- HY-137833
-
Naphthol AS-BI β-D-Glucuronide
|
Biochemical Assay Reagents
|
Naphthol AS-BI β-D-Glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W145687
-
Diosgenin-3-O-Β-D-Glucuronide
|
Biochemical Assay Reagents
|
Diosgenin-3-O-β-D-sodium glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W145619
-
|
Biochemical Assay Reagents
|
4-Nitrophenyl α-D-Glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-137869
-
5-Bromo-6-chloro-3-indolyl β-D-Glucuronide cyclohexylammonium
|
Biochemical Assay Reagents
|
Magenta-β-D-GlcA is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-137301S
-
|
Mycophenolic acid glucuronide-d3 is the deuterium labeled Mycophenolic acid glucuronide[1].
|
-
-
- HY-143911S
-
|
Acetaminophen glucuronide-d3 is the deuterium labeled Acetaminophen glucuronide[1].
|
-
-
- HY-143927S
-
|
Belinostat glucuronide-d5 is the deuterium labeled Belinostat glucuronide[1].
|
-
-
- HY-143957S
-
|
Fenretinide glucuronide-d4 is the deuterium labeled Fenretinide glucuronide[1].
|
-
-
- HY-144201S
-
|
Serotonin glucuronide-d4 is the deuterium labeled Serotonin glucuronide[1].
|
-
-
- HY-151706S
-
|
Temazepam glucuronide-d5 is a deuterium labeled Temazepam glucuronide[1].
|
-
-
- HY-125370S
-
|
Phenylephrine glucuronide-d3 is deuterium labeled Phenylephrine glucuronide.
|
-
-
- HY-154762S
-
|
Acetaminophen glucuronide-d4 is deuterated labeled Acetaminophen glucuronide.
|
-
-
- HY-113093S
-
|
Ethyl glucuronide-d5is the deuterium labeledEthyl glucuronide(HY-113093) . Ethyl glucuronide is an endogenous metabolite .
|
-
-
- HY-151027S
-
|
Androsterone-d4 glucuronide is the deuterium labeled Androsterone glucuronide[1].
|
-
-
- HY-132618S
-
|
N-Acetyltyramine Glucuronide-d3 is the deuterium labeled N-Acetyltyramine Glucuronide[1].
|
-
-
- HY-113104S
-
|
Androsterone glucuronide-d4 (sodium) is the deuterium labeled Androsterone glucuronide sodium[1].
|
-
-
- HY-144247S
-
|
Edaravone glucuronide-d5 (sodium) is the deuterium labeled Edaravone glucuronide sodium[1].
|
-
-
- HY-141914S
-
|
Cortisol-21-glucuronide-d4 (sodium) is the deuterium labeled Cortisol-21-glucuronide[1].
|
-
-
- HY-143929S
-
|
Bazedoxifene-5-glucuronide-d4 is the deuterium labeled Bazedoxifene-5-glucuronide[1].
|
-
-
- HY-135391S
-
|
Ezetimibe phenoxy glucuronide-d4 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
|
-
-
- HY-135582S
-
|
Raloxifene 4'-glucuronide-d4 is deuterated labeled Raloxifene 4'-glucuronide (HY-135582). Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression .
|
-
-
- HY-144166S
-
|
Silodosin glucuronide-d4 (lithium) is the deuterium labeled Silodosin glucuronide lithium[1].
|
-
-
- HY-135581S1
-
|
Raloxifene 6-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 6-glucuronide. Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression[1][2][3].
|
-
-
- HY-135582S1
-
|
Raloxifene 4'-glucuronide-d4 (lithium) is deuterium labeled Raloxifene 4'-glucuronide. Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. [1][2]. Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression[3].
|
-
-
- HY-135391S1
-
|
Ezetimibe phenoxy glucuronide-d4-1 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2][3].
|
-
-
- HY-136307S
-
|
Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum[1].
|
-
-
- HY-W016034S
-
|
Acetaminophen glucuronide-d3 sodium salt is the deuterium labeled Acetaminophen glucuronide sodium salt.
|
-
-
- HY-143915S
-
|
Amitriptyline-N-glucuronide-d3 is the deuterium labeled Amitriptyline-N-glucuronide[1].
|
-
-
- HY-113018S
-
|
Ibuprofen acyl-β-D-glucuronide-d3 is the deuterium labeled Ibuprofen acyl-β-D-glucuronide[1].
|
-
-
- HY-G0020S1
-
|
Nicotine N-β-D-glucuronide-d3 (Nicotine N-glucuronide-d3) is a deuterium labeled compound.
|
-
-
- HY-W588194S
-
|
(±)-Cotinine-N-β-Glucuronide-d3 is deuterated labeled (±)-Cotinine-N-β-Glucuronide.
|
-
-
- HY-W008917S1
-
|
Estrone β-D-glucuronide-d4 (sodium) is deuterium labeled Estrone beta-D-glucuronide sodium salt.
|
-
-
- HY-141942S
-
|
Dehydroepiandrosterone-3-o-glucuronide-d6 is the deuterium labeled Dehydroepiandrosterone-3-o-glucuronide[1].
|
-
-
- HY-143953S
-
|
Estrone ß-D-Glucuronide-d4 (lithium) is the deuterium labeled Estrone ß-D-Glucuronide[1].
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- HY-132480S
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Ciclopirox-d11 β-D-Glucuronide is the deuterium labeled Ciclopirox β-D-Glucuronide[1].
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- HY-118774S
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Propofol-d17 β-D-glucuronide is the deuterium labeled Propofol β-D-glucuronide[1].
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- HY-142598S
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Serotonin-d4 β-D-glucuronide is the deuterium labeled Serotonin β-D-glucuronide[1].
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- HY-142266S
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Retigabine N-β-D-glucuronide-d4 is the deuterium labeled Retigabine N-β-D-glucuronide[1].
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- HY-137522S
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Zidovudine O-β-D-glucuronide-d3 (sodium) (3'-Azido-3'-deoxythymidine β-D-glucuronide-d3 (sodium)) is a deuterium labeled Zidovudine O-β-D-glucuronide (sodium) (HY-137522). Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection .
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- HY-141903S
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Taurocholic acid-3-o-glucuronide-d4 is the deuterium labeled Taurocholic acid-3-o-glucuronide[1].
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- HY-122813S1
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Dabigatran acyl-β-D-glucuronide-d3 (TFA) is the deuterium labeled Dabigatran Acyl-β-D-Glucuronide trifluoroacetate[1].
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- HY-154772S
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trans-3’-Hydroxycotinine-O-β-glucuronide-d3 is deuterated labeled trans-3’-Hydroxycotinine-O-β-glucuronide.
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- HY-142581S
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1-Naphthol β-D-glucuronide-d7 (sodium) is the deuterium labeled 1-Naphthol β-D-glucuronide sodium[1].
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- HY-W040047S
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Pregnanediol 3-glucuronide- 13C5 is 13C-labeled Pregnanediol (HY-107850) Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo.
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- HY-137083S
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Trifluoperazine N-glucuronide-d3 is deuterium labeled Trifluoperazine N-Glucuronide. Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation[1].
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- HY-141945S
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Taurochenodeoxycholic acid-3-o-glucuronide-d4 (disodium) is the deuterium labeled Taurochenodeoxycholic acid-3-o-glucuronide[1].
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- HY-137912S1
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Resveratrol-3-O-beta-D-glucuronide- 13C6 is deuterium labeled trans-Resveratrol-3-O-β-D-Glucuronide.
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- HY-142119S
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5-Hydroxy tryptophol β-D-glucuronide-d4 is the deuterium labeled 5-Hydroxy tryptophol β-D-glucuronide[1].
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- HY-120201S
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7-Hydroxy Coumarin-d5 β-D-glucuronide (sodium) is the deuterium labeled 7-Hydroxy Coumarin β-D-glucuronide sodium[1].
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- HY-150985S
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2,2'-Dichloro bisphenol a mono-D-glucuronide-d12 is the deuterium labeled 2,2'-Dichloro bisphenol a mono-D-glucuronide[1].
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- HY-132723S
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17β-Estradiol-3-β-D-glucuronide-d3 is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].
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- HY-132723AS
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17β-Estradiol-3-β-D-glucuronide-d3 (sodium) is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].
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- HY-142279S
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17β-Estradiol 17-acetate 3-β-D-glucuronide-d3 is the deuterium labeled 17β-Estradiol 17-acetate 3-β-D-glucuronide[1].
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- HY-126373S1
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SN-38 glucuronide- 13C6 is the 13C labeled SN-38 glucuronide (HY-126373) . SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer .
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- HY-118634S
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trans-Resveratrol-4'-O-D-Glucuronide-d4 (R-4G-d4) is deuterium labeled trans-Resveratrol-4'-O-D-Glucuronide.
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- HY-154774S
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Tetrahydro-11-deoxy-Cortisol-d5-21-O-β-Glucuronide is deuterated labeled Tetrahydro-11-deoxy-Cortisol.
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- HY-125678S
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Jasmine lactone-d2 is deuterated labeled (±)-Cotinine-N-β-Glucuronide (HY-W588194).
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- HY-B0947S1
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Sulfanitran- 13C6 is the 13C labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
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Cat. No. |
Product Name |
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Classification |
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- HY-137522
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3'-Azido-3'-deoxythymidine β-D-Glucuronide sodium
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Azide
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Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection . Zidovudine O-β-D-glucuronide (sodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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