1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. MAC glucuronide linker-2

MAC glucuronide linker-2 

Cat. No.: HY-44222
Handling Instructions

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

MAC glucuronide linker-2 Chemical Structure

MAC glucuronide linker-2 Chemical Structure

CAS No. : 229977-57-5

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Estimated Time of Arrival: December 31
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Description

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Cleavable

 

Molecular Weight

455.41

Formula

C₂₀H₂₅NO₁₁

CAS No.

229977-57-5

SMILES

O=C(OC)[[email protected]@H](O1)[[email protected]@H](OC(C)=O)[[email protected]](OC(C)=O)[[email protected]@H](OC(C)=O)[[email protected]@H]1OC2=CC=C(CO)C=C2N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (439.16 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1958 mL 10.9791 mL 21.9582 mL
5 mM 0.4392 mL 2.1958 mL 4.3916 mL
10 mM 0.2196 mL 1.0979 mL 2.1958 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Keywords:

MAC glucuronide linker-2MAC glucuronide linker2MAC glucuronide linker 2ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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MAC glucuronide linker-2
Cat. No.:
HY-44222
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