1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. Ezetimibe phenoxy glucuronide-d4

Ezetimibe phenoxy glucuronide-d4  (Synonyms: Ezetimibe glucuronide-d4; Ezetimibe β-D-glucuronide-d4)

Cat. No.: HY-135391S
Handling Instructions

Ezetimibe phenoxy glucuronide-d4 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].

For research use only. We do not sell to patients.

Ezetimibe phenoxy glucuronide-d<sub>4</sub> Chemical Structure

Ezetimibe phenoxy glucuronide-d4 Chemical Structure

CAS No. : 1426174-41-5

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Description

Ezetimibe phenoxy glucuronide-d4 is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].

In Vivo

After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

589.57

Formula

C30H25D4F2NO9

CAS No.
SMILES

O[[email protected]]([[email protected]]([[email protected]@H]([[email protected]@H](C(O)=O)O1)O)O)[[email protected]@H]1OC2=CC=C([[email protected]]([[email protected]]3CC[[email protected]@H](C4=CC=C(F)C=C4)O)N(C5=C([2H])C([2H])=C(F)C([2H])=C5[2H])C3=O)C=C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ezetimibe phenoxy glucuronide-d4
Cat. No.:
HY-135391S
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