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Cat. No.: HY-126423

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Isorhamnetin 3-glucuronide

(Synonyms: Isorhamnetin 3-O-glucuronide)

Isorhamnetin 3-glucuronide is a potent anticancer agent. Isorhamnetin 3-glucuronide shows anti-proliferative activity. Isorhamnetin 3-glucuronide induces Apoptosis and cell cycle arrest at S-phase.

For research use only. We do not sell to patients.

CAS No.: 36687-76-0
Formula: C₂₂H₂₀O₁₃
Molecular Weight:492.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Isorhamnetin 3-glucuronide Chemical Structure

CAS No.: 36687-76-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Isorhamnetin 3-glucuronide (0-100 µM; 48 h) shows anti-proliferative activity in a dose-dependent manner for MCF-7 cells^[1].
Isorhamnetin 3-glucuronide (0-100 µM; 48 h) induces apoptosis and cell cycle arrest at S-phase in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[1]

Cell Line:

MCF-7 cells
Concentration:

0, 25, 50, 100 µM
Incubation Time:

48 h
Result:

Inhibited cell proliferation in a dose-dependent manner.

Apoptosis Analysis^[1]

Cell Line:

MCF-7 cells
Concentration:

25, 100 µM
Incubation Time:

48 h
Result:

Induced apoptosis with the rate of 16.8%, 49.8% at 25, 100 µM, respectively.

Cell Cycle Analysis^[1]

Cell Line:

MCF-7 cells
Concentration:

0, 50, 100 µM
Incubation Time:

48 h
Result:

Induced cell cycle arrest at S-phase.

Chemical Information

CAS No. 36687-76-0
Molecular Weight 492.39
Formula C₂₂H₂₀O₁₃
SMILES

O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(C3=CC=C(O)C(OC)=C3)OC4=CC(O)=CC(O)=C4C2=O
Synonyms

Isorhamnetin 3-O-glucuronide
Structure Classification
- Flavonoids
- Flavones
Initial Source
- Endogenous metabolite
human plasma
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu Q, et al. Differential Effects of Quercetin and Two of Its Derivatives, Isorhamnetin and Isorhamnetin-3-glucuronide, in Inhibiting the Proliferation of Human Breast-Cancer MCF-7 Cells. J Agric Food Chem. 2018 Jul 11;66(27):7181-7189. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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Isorhamnetin 3-glucuronide

High-Throughput Bioactive Compound Library

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Isorhamnetin 3-glucuronide Related Classifications

HY-126423 Related Classifications