FDGlcU
Based on 1 Customer Validation
FDGlcU can be used as a fluorescent probe for non-invasively image with a high level of fluorescent activity. FDGlcU is non-fluorescent when the fluorescein is conjugated with two mono-glucuronides (Ex/Em=480/514 nm).
For research use only. We do not sell to patients.
- Purity: 96.00%
- CAS No.: 209540-67-0
- Formula: C39H28F5NO18
- Molecular Weight:893.63
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
FDGlcU (0.5 μg/mL; 12 h) shows enzymatic activity and inhibits βG activity in live bacteria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
Whole-body imaging for intestinal βG activity[1]:
1. On the day of imaging, gavage mice with 50 μL of DDW, FDGlcU (7.3 μM/kg), and fluorescein (7.3 μM/kg). 2. Anesthetize mice with isoflurane and whole-body optical images using an IVIS spectrum optical imaging system with a GFP filter set. 3. In biodistribution study, mice are sacrificed 3 hour after gavaged with FDGlcU or fluorescein (λex =480 nm, λem =514 nm).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 209540-67-0
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Appearance Solid
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Molecular Weight 893.63
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Formula C39H28F5NO18
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Color Light yellow to yellow
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SMILES
O=C1OC2(C3=CC=C(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)C(O)=O)C=C3OC5=CC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=CC=C52)C7=CC=C(NC(C8=C(C(F)=C(C(F)=C8F)F)F)=O)C=C71
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)