1. Metabolic Enzyme/Protease
  2. Drug Metabolite Endogenous Metabolite
  3. Acetaminophen glucuronide

Acetaminophen glucuronide  (Synonyms: APAP-glu)

Cat. No.: HY-113083 Purity: ≥99.0%
COA Handling Instructions

Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005). Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.

For research use only. We do not sell to patients.

Acetaminophen glucuronide Chemical Structure

Acetaminophen glucuronide Chemical Structure

CAS No. : 16110-10-4

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Based on 1 publication(s) in Google Scholar

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Description

Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen (HY-66005)[1][2]. Acetaminophen is a selective cyclooxygenase-2 (COX-2) inhibitor and a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[3][4].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Acetaminophen is metabolized in the liver mainly by glucuronidation and sulfation, thus generating the nontoxic metabolites, Acetaminophen glucuronide (APAP-glu). Acetaminophen glucuronide is a substrate for both canalicular Mrp2 and basolateral Mrp3 in rodents[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

327.29

Formula

C14H17NO8

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=CC=C(C=C2)NC(C)=O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

References
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Acetaminophen glucuronide Related Classifications

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Product Name:
Acetaminophen glucuronide
Cat. No.:
HY-113083
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