SN-38 glucuronide-13C6
Based on 1 Customer Validation
SN-38 glucuronide-13C6 is the 13C labeled SN-38 glucuronide (HY-126373). SN-38 glucuronide is an inactive metabolite of the cancer agent Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer.
For research use only. We do not sell to patients.
- Purity: 96.13%
- Formula: C2213C6H28N2O11
- Molecular Weight:574.48
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 121080-63-5
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Appearance Solid
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Molecular Weight 574.48
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Formula C2213C6H28N2O11
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Color Light yellow to yellow
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SMILES
CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=N[13C]5=[13CH][13CH]=[13C](O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)[13CH]=[13C]51
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Synonyms
SN-38G-13C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (174.07 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7407 mL | 8.7035 mL | 17.4070 mL | 43.5176 mL |
| 5 mM | 0.3481 mL | 1.7407 mL | 3.4814 mL | 8.7035 mL | |
| 10 mM | 0.1741 mL | 0.8704 mL | 1.7407 mL | 4.3518 mL | |
| 15 mM | 0.1160 mL | 0.5802 mL | 1.1605 mL | 2.9012 mL | |
| 20 mM | 0.0870 mL | 0.4352 mL | 0.8704 mL | 2.1759 mL | |
| 25 mM | 0.0696 mL | 0.3481 mL | 0.6963 mL | 1.7407 mL | |
| 30 mM | 0.0580 mL | 0.2901 mL | 0.5802 mL | 1.4506 mL | |
| 40 mM | 0.0435 mL | 0.2176 mL | 0.4352 mL | 1.0879 mL | |
| 50 mM | 0.0348 mL | 0.1741 mL | 0.3481 mL | 0.8704 mL | |
| 60 mM | 0.0290 mL | 0.1451 mL | 0.2901 mL | 0.7253 mL | |
| 80 mM | 0.0218 mL | 0.1088 mL | 0.2176 mL | 0.5440 mL | |
| 100 mM | 0.0174 mL | 0.0870 mL | 0.1741 mL | 0.4352 mL |
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