117 Results for "

bacterial metabolite

" in MedChemExpress (MCE) Product Catalog:
Products (117)

117 Results for "bacterial metabolite" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-B1367
CAS No.: 7421-40-1
Carbenoxolone disodium is the active metabolite of Glycyrrhizic acid (HY-N0184) and the inhibitor of human 11β-HSD and bacterial 3α, 20β-HSD . Carbenoxolone disodium is an uncoupling agent for gap junctions and a potent inhibitor of Vaccinia virus replication . Carbenoxolone disodium is used for the study of peptic, esophageal and oral ulceration and inflammation. Carbenoxolone disodium inhibits Vaccinia virus replication.
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6
6 Cited Publications
Cat. No.: HY-N7378
CAS No.: 115819-92-6
Synonyms: 1-Hydroxy-2-piperidinecarboxylic acid; NHP
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection .
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5
5 Cited Publications
Cat. No.: HY-N0904
CAS No.: 39262-14-1
Synonyms: Ginsenoside compound K; Ginsenoside K
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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3
3 Cited Publications
Cat. No.: HY-A0132
CAS No.: 7512-17-6
Synonyms: N-Acetyl-2-amino-2-deoxy-D-glucose
N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose), the D isomer of N-acetylglucosamine, is an orally active monosaccharide derivative of glucose with anti-tumor and anti-inflammation properties. N-Acetyl-D-Glucosamine is also a bacterial metabolite, which is found in Escherichia coli. N-Acetyl-D-Glucosamine can induce yeast-mycelial conversion in Candida albicans. N-Acetyl-D-Glucosamine also enhances healing of cartilaginous injuries in rabbits .
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3
3 Cited Publications
Cat. No.: HY-N1029
CAS No.: 3542-72-1
Synonyms: Mangiferitin
Norathyriol (Mangiferitin) is a natural metabolite of Mangifera. Norathyriol inhibits α-glucosidase in a noncompetitive manner with an IC50 of 3.12 μM . Norathyriol inhibits PPARα, PPARβ, and PPARγ with IC50s of 92.8 µM, 102.4 µM, and 153.5 µM, respectively . Antioxidant, anticancer, antimicrobial, anti-inflammatory, anti-bacterial activities.
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1
1 Cited Publications
Cat. No.: HY-135470
CAS No.: 13411-16-0
Purity:  98.70%
Synonyms: P-7138
Target:  

Bacterial

Research Areas:  

Infection

Nifurpirinol (P-7138) is a selective prosubstrate of bacterial nitroreductase (NTR). NTR catalyzes the reduction of nifurpirinol to generate cytotoxic metabolites that induce apoptosis in target cells. Nifurpirinol selectively ablates NTR-expressing cells such as pancreatic β cells, osteoblasts, dopaminergic neurons, and podocytes in transgenic zebrafish models. Nifurpirinol can be used in regeneration studies and disease modeling such as focal segmental glomerulosclerosis (FSGS) .
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1
1 Cited Publications
Cat. No.: HY-A0111
CAS No.: 65052-63-3
Synonyms: Ro 15-8074; Deacetoxycefotaxime
Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis .
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1
1 Cited Publications
Cat. No.: HY-N0606
CAS No.: 105558-26-7
Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 treatment in human retinal cells induces Nrf2 activation.
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1
1 Cited Publications
Cat. No.: HY-113474
CAS No.: 775-01-9
Purity:  98.56%
3,4‑Dihydroxymandelic acid is a metabolite of Norepinephrine (HY-13715) with free radical scavenging and antioxidant activities. 3,4-Dihydroxymandelic acid acts as a chemoattractant for enterohaemorrhagic Escherichia coli (EHEC), regulates virulence gene expression and bacterial adhesion to intestinal epithelial cells in a QseC-dependent manner, and targets EHEC to preferred infection sites. 3,4‑Dihydroxymandelic acid can be used in studies related to oxidative stress and enterohaemorrhagic Escherichia coli infection .
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Cat. No.: HY-W015450
CAS No.: 923-16-0
Synonyms: D-Alanyl-D-alanine; H-D-Ala-D-Ala-OH
D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase .
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Cat. No.: HY-N13356
CAS No.: 5652-48-2
Synonyms: gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .
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Cat. No.: HY-138877
CAS No.: 13147-57-4
Phosphoglycolic acid is a metabolite and a bacterial cytoplasmic component. Phosphoglycolic acid acts as a by-product generated during the preparation of phosphoglycolohydroxamic acid via hydrolysis of ethyl phosphoglycolate. Phosphoglycolic acid also functions as an active component of postbiotics .
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Cat. No.: HY-48814
CAS No.: 570-63-8
Target:  

Bacterial FXR

Research Areas:  

Infection Inflammation/Immunology

3-Epideoxycholic acid is a secondary bile acid and a microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR in dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exerts anti-inflammatory activity. 3-Epideoxycholic acid can promote the growth of the bacterium Bacteroides. 3-Epideoxycholic acid can be used in research related to inflammatory and immune diseases as well as bacterial infections .
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Cat. No.: HY-115249
CAS No.: 1010-93-1
Purity:  99.88%
Target:  

Bacterial

Research Areas:  

Infection

Metronidazole acetic acid is a metabolite of Metronidazole (HY-B0318) and exhibits mutagenic activity in bacterial .
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Cat. No.: HY-125407
CAS No.: 126127-31-9
Purity:  95.9%
Synonyms: N-Palmitoyl serinol
Target:  

Cannabinoid Receptor

Research Areas:  

Inflammation/Immunology

Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin .
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Cat. No.: HY-W014701
CAS No.: 31519-22-9
1,4-Dihydroxy-2-naphthoic acid is an aryl hydrocarbon receptor (AhR) agonist. 1,4-Dihydroxy-2-naphthoic acid is also a bacterially derived metabolite and has anti-inflammatory activity .
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Cat. No.: HY-128736C
Purity:  89.70%
L-2-Phosphoglyceric acid sodium hydrate is an endogenous metabolite. L-2-Phosphoglyceric acid sodium hydrate serves as a substrate for phosphatases and releases inorganic phosphate upon catalytic dephosphorylation. L-2-Phosphoglyceric acid sodium hydrate is upregulated in human oral fibroblasts treated with Porphyromonas gingivalis bacterial extracellular vesicles. L-2-Phosphoglyceric acid sodium hydrate is useful for research related to prostate cancer and periodontitis .
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Cat. No.: HY-128736
CAS No.: 23295-92-3
L-2-Phosphoglyceric acid is an endogenous metabolite. L-2-Phosphoglyceric acid serves as a substrate for phosphatases and releases inorganic phosphate upon catalytic dephosphorylation. L-2-phosphoglyceric acid is upregulated in human oral fibroblasts treated with Porphyromonas gingivalis bacterial extracellular vesicles. L-2-Phosphoglyceric acid is useful for research related to prostate cancer and periodontitis .
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Cat. No.: HY-N9934
CAS No.: 2922-42-1
Synonyms: 3-DHS; 5-Dehydroshikimic acid
(-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions .
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Cat. No.: HY-N7921
CAS No.: 1006683-97-1
Urolithin M6 is a polyhydroxy-rich metabolite with potential antioxidant activity. Urolithin M6 is produced by intestinal microbial metabolism and may act as an analog of tannic acid compounds. The production of Urolithin M6 in humans requires specific bacterial 3-dehydroxylase activity, which provides a new mechanism for its biotransformation. The metabolic profile of Urolithin M6 helps to stratify volunteers and further explore its potential role in health and disease .
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