1. Anti-infection
  2. Bacterial Fungal
  3. (±)-Lomatin

(±)-Lomatin (Xanthogalol) (Compound 10) is a coumarin-type secondary metabolite. (±)-Lomatin can be found in Coleonema album. (±)-Lomatin can be used for the research of bacterial infections, mycobacterial infections, and fungal infections.

For research use only. We do not sell to patients.

(±)-Lomatin

(±)-Lomatin Chemical Structure

CAS No. : 1147-25-7

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Description

(±)-Lomatin (Xanthogalol) (Compound 10) is a coumarin-type secondary metabolite. (±)-Lomatin can be found in Coleonema album. (±)-Lomatin can be used for the research of bacterial infections, mycobacterial infections, and fungal infections[1].

Cellular Effect
Cell Line Type Value Description References
CHO Inhibition
142.315 %
Compound: LOMATIN
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
[PMID: 23571415]
CHO Inhibition
92.9117 %
Compound: LOMATIN
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
[PMID: 23571415]
In Vitro

(±)-Lomatin (Xanthogalol) (Compound 10) (0.019-2.5 mg/mL; 24 h) inhibits the growth of E. coli, P. aeruginosa, E. faecalis, S. aureus, C. albicans, and M. tuberculosis with MIC values ranging from 0.156 mg/mL to 1 mg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

246.26

Formula

C14H14O4

CAS No.
SMILES

O=C1OC2=C(C=C1)C=CC=3OC(C)(C)C(O)CC32

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(±)-Lomatin
Cat. No.:
HY-N11685
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