Search Result
Results for "
glucose glycoside
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N0755
-
|
|
Insulin Receptor
GLUT
NF-κB
p38 MAPK
Autophagy
|
Metabolic Disease
Endocrinology
Cancer
|
|
Rhoifolin is a flavone glycoside can be isolated from Rhus succedanea. Rhoifolin has anti-diabetic effect acting through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation. Rhoifolin has an anti-inflammatory action via multi-level regulation of inflammatory mediators. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. Rhoifolin also has cytotoxic activity against different cancer cell lines .
|
-
-
- HY-P2869
-
|
EC 3.2.1.23; GAL
|
Glycosidase
|
Metabolic Disease
|
|
β-Galactosidase, E. coli (EC 3.2.1.23; GAL) is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. β-Galactosidase, E. coli can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides .
|
-
-
- HY-B0481
-
|
BAY1099; BAY-m1099
|
Glycosidase
AMPK
Reactive Oxygen Species (ROS)
|
Metabolic Disease
|
|
Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called α-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets .
|
-
-
- HY-N0668
-
|
|
GLUT
Amylases
NF-κB
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
|
-
-
- HY-N0466
-
|
|
Glycosidase
HMG-CoA Reductase (HMGCR)
Fatty Acid Synthase (FASN)
LDLR
|
Others
|
|
Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC50 value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity .
|
-
-
- HY-P2875
-
|
|
Endogenous Metabolite
|
Others
|
|
Hemicellulase is a hemicellulose-targeting hydrolase that breaks down the binding of glucose and polymers to water molecules present in plant fibers. Hemicellulase specifically degrades hemicellulose (such as xylan and mannan) in plant cell walls by hydrolyzing β-1,4-xylosidic bonds and ester bonds (such as acetyl and ferulic acid ester bonds). Hemicellulase relies on the synergistic action of the glycoside hydrolase (GH) and carbohydrate esterase (CE) families to achieve efficient hydrolysis through acid-base catalysis (such as Glu/Asp residues) and substrate binding pockets. Hemicellulase can be used in the food industry (such as improving bread texture), biofuel production (lignocellulose pretreatment) and paper industry (biobleaching) .
|
-
-
- HY-N6082
-
|
|
Apoptosis
Bcl-2 Family
Caspase
TGF-beta/Smad
Bacterial
|
Infection
Metabolic Disease
Inflammation/Immunology
|
|
Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
|
-
-
- HY-N12445
-
|
|
Topoisomerase
Caspase
Apoptosis
SOD
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Quercetin-3'-O-glucoside is an orally active flavonoid glycoside. Quercetin-3'-O-glucoside reduces liver glucose-6-phosphatase activity, alters serum insulin and glucose levels, and regulates the activities of antioxidant enzymes in the liver and kidney. Quercetin-3'-O-glucoside inhibits DNA topoisomerase II, induces S-phase cell cycle arrest and caspase-3-mediated apoptosis in hepatocellular carcinoma cells. Quercetin-3'-O-glucoside selectively inhibits EGFR-mediated signaling pathways targeting AKT, ERK1/2, FAK and MEK1/2. Quercetin-3'-O-glucoside inhibits growth factor-induced migration and invasion in pancreatic cancer cells. Quercetin-3'-O-glucoside exerts free radical scavenging effects. Quercetin-3'-O-glucoside is applicable to research related to pancreatic cancer, diabetes, hepatocellular carcinoma and malignant tumors .
|
-
-
- HY-P2741
-
|
E.C. 2.4.1.8
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Maltose phosphorylase is a dimerase which catalyzes the transformation of maltose and inorganic phosphate into β-D-glucose-1-phosphate and glucose. Maltose phosphorylases have been classified in family 65 of the glycoside hydrolases .
|
-
-
- HY-W142618
-
|
|
Biochemical Assay Reagents
|
Others
|
|
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
|
-
-
- HY-N2093
-
Vicine
2 Publications Verification
|
Drug Metabolite
|
Cardiovascular Disease
Metabolic Disease
|
|
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food .
|
-
-
- HY-P2869I
-
|
|
Glycosidase
|
Metabolic Disease
|
|
β-Galactosidase, Sweet almond is a glycoside hydrolase that hydrolyzes the β-glycosidic bonds formed between galactose and its organic moieties. β-Galactosidase, Sweet almond can hydrolyze lactose to form glucose and galactose, and enter glycolysis; it can also catalyze the transgalactosylation of lactose into allolactose; allolactose can be cracked into monosaccharides .
|
-
-
- HY-N0466R
-
|
|
Reference Standards
Glycosidase
HMG-CoA Reductase (HMGCR)
Fatty Acid Synthase (FASN)
LDLR
|
Others
|
|
Rebaudioside A (Standard) is the analytical standard of Rebaudioside A. This product is intended for research and analytical applications. Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC50 value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity.
|
-
-
- HY-N0755R
-
|
|
Reference Standards
Insulin Receptor
GLUT
NF-κB
p38 MAPK
Autophagy
|
Metabolic Disease
Endocrinology
Cancer
|
|
Rhoifolin (Standard) is the analytical standard of Rhoifolin. This product is intended for research and analytical applications. Rhoifolin is a flavone glycoside can be isolated from Rhus succedanea. Rhoifolin has anti-diabetic effect acting through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation. Rhoifolin has an anti-inflammatory action via multi-level regulation of inflammatory mediators. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. Rhoifolin also has cytotoxic activity against different cancer cell lines .
|
-
-
- HY-N0668R
-
|
|
GLUT
Amylases
NF-κB
Reference Standards
|
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Rubusoside (Standard) is the analytical standard of Rubusoside. This product is intended for research and analytical applications. Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
|
-
-
- HY-N16640
-
-
-
- HY-N15691
-
|
|
Keap1-Nrf2
NF-κB
|
Metabolic Disease
Inflammation/Immunology
|
|
Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes .
|
-
-
- HY-N9525
-
|
|
Others
|
Others
|
|
Limocitrin 3-β-D-glucose is a flavonoid glycoside .
|
-
-
- HY-N11573
-
|
|
Others
|
Others
|
|
Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (compound 1) is a flavonoid glycoside that can be found in Euonymus fortune.
|
-
-
- HY-N15691A
-
|
|
Keap1-Nrf2
NF-κB
|
Metabolic Disease
Inflammation/Immunology
|
|
(E)-Tadehaginoside is the E-isomer of Tadehaginoside (HY-N15691). Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes .
|
-
-
- HY-N6082R
-
|
|
Reference Standards
Apoptosis
Bacterial
Bcl-2 Family
Caspase
TGF-beta/Smad
|
Infection
Metabolic Disease
Inflammation/Immunology
|
|
Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
|
-
-
- HY-N18046
-
|
|
Drug Derivative
|
Cancer
|
|
Otophylloside Q is a pregnane glycoside (C-21 steroidal glycoside) isolated from the roots of Cynanchum otophyllum. With caudatin (HY-N1983), an anticancer agent, as its aglycone, Otophylloside Q contains a sugar chain composed of cymarose, oleandrose and glucose units .
|
-
-
- HY-P2766B
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Trehalase, Porcine (EC 3.2.1.28) is a glycoside hydrolase enzyme located in on the brush border of the small intestine that catalyzes the conversion of trehalose to glucose.
|
-
-
- HY-N17531
-
|
|
Drug Derivative
|
Others
|
|
4-(β-D-Glucopyranosyloxy) benzenepropanoic acid is a phenolic acid glycoside natural product, which has an O-β-D-glucoside structure formed by a phenylpropanoic acid derivative and glucose .
|
-
-
- HY-N17435
-
|
|
Drug Derivative
|
Others
|
|
Phloridzin 2''-acetate is a dihydrochalcone glycoside found in the leaves of Kalmia latifolia .
|
-
-
- HY-P2775A
-
|
|
Glycosidase
|
Metabolic Disease
|
|
β-Glucosidase(thermostable) is a glucosidase enzyme located in on the brush border of the small intestine that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose). β-Glucosidase(thermostable) is an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-P2763A
-
|
|
Glycosidase
|
Metabolic Disease
|
|
β-Glucanase 2(thermostable) is a glucosidase enzyme located in on the brush border of the small intestine that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose). β-Glucanase 2 (thermostable) is an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-P2763B
-
|
|
Glycosidase
|
Metabolic Disease
|
|
β-Glucanase 1(thermostable) is a glucosidase enzyme located in on the brush border of the small intestine that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose). β-Glucanase 1 (thermostable) is an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E70898
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Trehalose-6-phosphate hydrolase, Escherichia coli (EC 3.2.1.93), belongs to the hydrolase family and is a glycosidase that hydrolyzes O- and S-glycoside compounds. Trehalose-6-phosphate hydrolase participates in the metabolism of starch and sucrose. Its substrates are α,α'-trehalose-6-phosphate and water, and its products are D-glucose and D-glucose-6-phosphate.
|
-
-
- HY-E70898A
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Trehalose-6-phosphate hydrolase, Bacillus subtilis (EC 3.2.1.93), belongs to the hydrolase family and is a glycosidase that hydrolyzes O- and S-glycoside compounds. Trehalose-6-phosphate hydrolase participates in the metabolism of starch and sucrose. Its substrates are α,α'-trehalose-6-phosphate and water, and its products are D-glucose and D-glucose-6-phosphate.
|
-
-
- HY-E71305H
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Saccharophagus degradans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305K
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Thermus thermophilus (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305A
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Caldicellulosiruptor saccharolyticus (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305I
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Thermobifida fusca (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305B
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Clostridium cellulovorans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305D
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Bacillus halodurans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Bacillus halodurans (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305J
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Thermotoga petrophila (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305E
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Pectobacterium carotovorum (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71305C
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 1A, Paenibacillus polymyxa (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-E71306
-
|
|
Glycosidase
|
Others
|
|
β-Glucosidase 3A, Bacteroides ovatus (EC 3.2.1.21) is a glucosidase enzyme that acts upon β1->4 bonds linking two glucose or glucose-substituted molecules (i.e., the disaccharide cellobiose) . β-Glucosidase is one of the cellulases, enzymes involved in the decomposition of cellulose and related polysaccharides; more specifically, an exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of glucose.
|
-
-
- HY-N18023
-
|
|
Others
|
Others
|
|
Kaempferol-3-O-β-D-Glucose-7-O-β-D-Gentianoside is a kaempferol glycoside found in the seeds of Lepidium apetalum Willd. Kaempferol-3-O-β-D-Glucose-7-O-β-D-Gentianoside shows no obvious inhibitory effect on Sodium oleate (HY-N1446B)-induced triglyceride overloading in liver cells .
|
-
-
- HY-N17897
-
|
|
Endogenous Metabolite
|
Others
|
|
Tubuloside E is a phenylethanoid glycoside compound that can be isolated from the whole plant of Cistanche tubulosa (Schrenk) Hook. f. (Orobanchaceae) .
|
-
-
- HY-W750858
-
|
|
Drug Derivative
Herbicide
|
Others
|
|
DIBOA-Glucoside is a glycoside derivative that can be found in cereal crops like rye, wheat, and maize. DIBOA-Glucoside is a stable, less toxic glucoside form of DIBOA. DIBOA-Glucoside, upon pest or pathogen attack, is hydrolyzed by an enzyme, releasing the toxic aglycone DIBOA and glucose, thereby deterring insects and suppressing weeds through an allelopathic effect .
|
-
-
- HY-N18008
-
|
|
Others
|
Others
|
|
Otophylloside P is a pregnane glycosid. Otophylloside P can be isolated from the roots of Cynanchum otophyllum .
|
-
-
- HY-E71366
-
|
|
Glycosidase
Endogenous Metabolite
|
Metabolic Disease
|
|
Endo-1,4-β-D-glucanase is a glycoside hydrolase that cleaves internal β-1,4-glycosidic bonds in cellulose and related β-D-glucans (β-D-Glucan) (HY-139413). Endo-1,4-β-D-glucanase randomly cuts long, insoluble cellulose polymer chains into shorter, soluble fragments such as oligosaccharides, thereby paving the way for further digestion into glucose .
|
-
-
- HY-N17976
-
|
|
Drug Derivative
|
Inflammation/Immunology
|
|
Scrophenoside A (compound 1) is a phenyl glycoside found in the stems of Picrorhiza scrophulariiflora.Scrophenoside A exhibits anti-asthma activity.Scrophenoside A can be used for the research of asthma .
|
-
-
- HY-N17139
-
|
|
Others
|
Inflammation/Immunology
|
|
6'-O-Glucopyranosylalbiflorin is a monoterpene glycoside compound containing two β-D-glucose units, which has bone formation-promoting effects. 0.01-10 μM 6'-O-Glucopyranosylalbiflorin shows significant activity against osteoblast MC3T3-E1 cells, promoting alkaline phosphatase activity and calcium deposition to stimulate osteoblast differentiation. 6'-O-Glucopyranosylalbiflorin can be used in research of osteoporosis. 6'-O-Glucopyranosylalbiflorin can be naturally extracted from the dried roots of Paeonia lactiflora Pall. (peony) from Vinh Phuc province, Vietnam .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W142618
-
|
|
Biochemical Assay Reagents
|
|
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-N0755
-
-
-
- HY-N0668
-
-
-
- HY-N0466
-
-
-
- HY-N6082
-
-
-
- HY-N12445
-
|
|
Malvaceae
Structural Classification
Flavonols
Flavonoids
Abelmoschus manihot (Linn.) Medicus
Plants
Source Classification
|
Topoisomerase
Caspase
Apoptosis
SOD
|
|
Quercetin-3'-O-glucoside is an orally active flavonoid glycoside. Quercetin-3'-O-glucoside reduces liver glucose-6-phosphatase activity, alters serum insulin and glucose levels, and regulates the activities of antioxidant enzymes in the liver and kidney. Quercetin-3'-O-glucoside inhibits DNA topoisomerase II, induces S-phase cell cycle arrest and caspase-3-mediated apoptosis in hepatocellular carcinoma cells. Quercetin-3'-O-glucoside selectively inhibits EGFR-mediated signaling pathways targeting AKT, ERK1/2, FAK and MEK1/2. Quercetin-3'-O-glucoside inhibits growth factor-induced migration and invasion in pancreatic cancer cells. Quercetin-3'-O-glucoside exerts free radical scavenging effects. Quercetin-3'-O-glucoside is applicable to research related to pancreatic cancer, diabetes, hepatocellular carcinoma and malignant tumors .
|
-
-
- HY-N2093
-
-
-
- HY-N0466R
-
|
|
Structural Classification
Trifolium hybridum L.
Terpenoids
Diterpenoids
Plants
Compositae
Endogenous metabolite
Source Classification
|
Reference Standards
Glycosidase
HMG-CoA Reductase (HMGCR)
Fatty Acid Synthase (FASN)
LDLR
|
|
Rebaudioside A (Standard) is the analytical standard of Rebaudioside A. This product is intended for research and analytical applications. Rebaudioside A is an orally effective steviol glycoside with high sweetness. Rebaudioside A acts as an inhibitor of α-glucosidase with an IC50 value of 35.01 μg/mL. Rebaudioside A increases the ATP/ADP ratio in β cells in a glucose-dependent manner, thereby inhibiting KATP channels, leading to membrane depolarization, calcium influx, and ultimately stimulating insulin secretion. Rebaudioside A activates the SREBP signaling pathway by inhibiting HMGCR, the rate-limiting enzyme in cholesterol synthesis, resulting in increased expression of LDLR on the cell surface, thus promoting the uptake of LDL-C in the blood. Rebaudioside A can be used for studies on blood glucose and lipid regulation as well as anti-obesity.
|
-
-
- HY-N0755R
-
|
|
Structural Classification
Rhus succedanea
Flavonoids
Flavones
Plants
Anacardiaceae
|
Reference Standards
Insulin Receptor
GLUT
NF-κB
p38 MAPK
Autophagy
|
|
Rhoifolin (Standard) is the analytical standard of Rhoifolin. This product is intended for research and analytical applications. Rhoifolin is a flavone glycoside can be isolated from Rhus succedanea. Rhoifolin has anti-diabetic effect acting through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation. Rhoifolin has an anti-inflammatory action via multi-level regulation of inflammatory mediators. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. Rhoifolin also has cytotoxic activity against different cancer cell lines .
|
-
-
- HY-N0668R
-
|
|
Structural Classification
other families
Terpenoids
Diterpenoids
Plants
Source Classification
|
GLUT
Amylases
NF-κB
Reference Standards
|
|
Rubusoside (Standard) is the analytical standard of Rubusoside. This product is intended for research and analytical applications. Rubusoside is a diterpene glycoside that is also a sweetener and solubilizer with anti-angiogenic, anti-cancer, anti-obesity, anti-allergic and anti-asthmatic effects. Rubusoside attenuates airway hyperresponsiveness and reduces inflammatory cells in bronchoalveolar lavage fluid (BALF), reducing OVA (HY-W250978)-induced airway inflammation. Rubusoside also prevents palmitic acid-induced lipotoxicity in pancreatic INS-1 cells, reduces the transport of human glucose transporters GLUT-1 and fructose GLUT-5, and inhibits NF-κB and α-amylase (α-amylase) .
|
-
-
- HY-N16640
-
-
-
- HY-N15691
-
-
-
- HY-N9525
-
-
-
- HY-N11573
-
-
-
- HY-N15691A
-
|
|
Leguminosae
Phenols
Polyphenols
Tadehagi triquetrum (L.) Ohashi
Plants
Source Classification
|
Keap1-Nrf2
NF-κB
|
|
(E)-Tadehaginoside is the E-isomer of Tadehaginoside (HY-N15691). Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes .
|
-
-
- HY-N6082R
-
|
|
Quinones
Structural Classification
Monophenols
Rheum palmatum L.
Anthraquinones
Polygonaceae
Phenols
Plants
Source Classification
|
Reference Standards
Apoptosis
Bacterial
Bcl-2 Family
Caspase
TGF-beta/Smad
|
|
Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
|
-
-
- HY-N18046
-
-
-
- HY-N17531
-
-
-
- HY-N17435
-
-
-
- HY-N18023
-
-
-
- HY-N17897
-
-
-
- HY-W750858
-
-
-
- HY-N18008
-
-
-
- HY-N17976
-
-
-
- HY-N17139
-
|
|
Structural Classification
Flavonoids
Paeonia lactiflora Pall.
Flavones
Plants
Paeoniaceae
Source Classification
|
Others
|
|
6'-O-Glucopyranosylalbiflorin is a monoterpene glycoside compound containing two β-D-glucose units, which has bone formation-promoting effects. 0.01-10 μM 6'-O-Glucopyranosylalbiflorin shows significant activity against osteoblast MC3T3-E1 cells, promoting alkaline phosphatase activity and calcium deposition to stimulate osteoblast differentiation. 6'-O-Glucopyranosylalbiflorin can be used in research of osteoporosis. 6'-O-Glucopyranosylalbiflorin can be naturally extracted from the dried roots of Paeonia lactiflora Pall. (peony) from Vinh Phuc province, Vietnam .
|
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: