1. Terpenoids and Glycosides

Rebaudioside A 

Cat. No.: HY-N0466 Purity: >98.0%
Handling Instructions

Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.

For research use only. We do not sell to patients.

Rebaudioside A Chemical Structure

Rebaudioside A Chemical Structure

CAS No. : 58543-16-1

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
500 mg USD 108 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels. Target: α-glucosidase [1] IC 50: 35.01 ug/mL In vitro: rebaudioside A stimulat the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner. In conclusion, the insulinotropic effect of rebaudioside A is mediated via inhibition of ATP-sensitive K+-channels and requires the presence of high glucose. [2] In vivo: in vivo mouse micronucleus test at doses up to 750 mg/kg bw and an unscheduled DNA synthesis test in rats at doses up to 2000 mg/kg bw, rebaudioside A do not cause any genotoxic effects at any of the doses tested.[3]

Solvent & Solubility
In Vitro: 

DMSO : ≥ 150 mg/mL (155.12 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0341 mL 5.1706 mL 10.3412 mL
5 mM 0.2068 mL 1.0341 mL 2.0682 mL
10 mM 0.1034 mL 0.5171 mL 1.0341 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

967.01

Formula

C₄₄H₇₀O₂₃

CAS No.

58543-16-1

SMILES

C[[email protected]]12[[email protected]@]3([H])[[email protected]@](C4)(CC[[email protected]]1([H])[[email protected]@](C)(CCC2)C(O[[email protected]@H]5O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]5O)CO)=O)C[[email protected]@](C4=C)(O[[email protected]@]6([H])[[email protected]@H]([[email protected]]([[email protected]](O)[[email protected]@H](CO)O6)O[[email protected]]7([H])O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]7O)CO)O[[email protected]]8([H])O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]8O)CO)CC3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Rebaudioside A
Cat. No.:
HY-N0466
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Rebaudioside A

Cat. No.: HY-N0466