1. Terpenoids and Glycosides

Rebaudioside A 

Cat. No.: HY-N0466 Purity: >98.0%
Data Sheet SDS Handling Instructions

Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.

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Rebaudioside A Chemical Structure

Rebaudioside A Chemical Structure

CAS No. : 58543-16-1

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Description

Rebaudioside A is a steviol glycoside, α-glucosidase inhibitor with IC50 of 35.01 μg/ml.can inhibit ATP-sensitive K+-channels. Target: α-glucosidase [1] IC 50: 35.01 ug/mL In vitro: rebaudioside A stimulat the insulin secretion from MIN6 cells in a dose- and glucose-dependent manner. In conclusion, the insulinotropic effect of rebaudioside A is mediated via inhibition of ATP-sensitive K+-channels and requires the presence of high glucose. [2] In vivo: in vivo mouse micronucleus test at doses up to 750 mg/kg bw and an unscheduled DNA synthesis test in rats at doses up to 2000 mg/kg bw, rebaudioside A do not cause any genotoxic effects at any of the doses tested.[3]

References
Molecular Weight

967.01

Formula

C₄₄H₇₀O₂₃

CAS No.

58543-16-1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 150 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Rebaudioside A
Cat. No.:
HY-N0466
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