Endo-1,4-β-D-glucanase 

Endo-1,4-β-D-glucanase is a glycoside hydrolase that cleaves internal β-1,4-glycosidic bonds in cellulose and related β-D-glucans (β-D-Glucan) (HY-139413). Endo-1,4-β-D-glucanase randomly cuts long, insoluble cellulose polymer chains into shorter, soluble fragments such as oligosaccharides, thereby paving the way for further digestion into glucose^[1][2].

Endo-1,4-β-D-glucanase is a regulated intracellular recycling protein that undergoes developmentally regulated trafficking through the Golgi apparatus, early endosomes, and vacuolar membranes, and can redistribute in response to cellulose synthesis inhibition^[1].
Endo-1,4-β-D-glucanase is a microtubule-dependent motor component, and some of its vesicular compartments exhibit linear plasma membrane movement that requires the involvement of intact microtubules^[1].
Endo-1,4-β-D-glucanase is a key component of the plant cellulose synthesis machinery. Its expression is associated with hypocotyl cell elongation under dark growth conditions, appears during the germination stage, reaches a peak in the growth stage, and disappears after the completion of elongation^[1].
Endo-1,4-β-D-glucanase is present in the intestinal digestive fluid of adult Hoplasoma unicolor, with an optimal pH of 5.3 and a specific activity of 0.69 U/mg^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

[Endo-1,4-β-D-glucanase]

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• [1]. Robert S, et al. An Arabidopsis endo-1,4-beta-D-glucanase involved in cellulose synthesis undergoes regulated intracellular cycling. Plant Cell. 2005;17(12):3378-3389.

  [2]. Uddin MM, et al. Evaluation of Cellulolytic Endo-1, 4-β-D-Glucanase Activity in the Digestive Fluid of Adult Phytophagous Beetle Hoplasoma unicolor. Tropical Life Sciences Research. 2021 Sep 30;32(3):53.