2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. β-D-Glucan

β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery. β-d-glucan is an enteric delivery vehicle for probiotics.

For research use only. We do not sell to patients.

β-D-Glucan Chemical Structure

β-D-Glucan Chemical Structure

CAS No. : 9041-22-9

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Based on 1 publication(s) in Google Scholar

β-D-Glucan Related Antibodies

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Description

β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery[1]. β-d-glucan is an enteric delivery vehicle for probiotics[2].

In Vitro

β-D-glucan dissolved in DMSO but not water inhibits MCF-7 cell proliferation in a concentration-dependent manner as measured by BrdU incorporation with an IC50 of ∼164 μg/mL. β-D-glucan dissolved in DMSO inhibits tamoxifen/endocrine-resistant LCC9 and LY2 cell proliferation with IC50 values of 4.6 and 24.2 μg/mL, respectively[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

β-D-Glucan Related Antibodies
CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

[beta-D-Glucan]
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Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

1M NaOH : 50 mg/mL (ultrasonic and adjust pH to 12 with NaOH)

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Purity & Documentation

Purity: ≥98.0%

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β-D-Glucan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-D-Glucan9041-22-9Toll-like Receptor (TLR)enteric delivery vehicleprobioticsnon-digestible polysaccharideDectin-1Toll-like receptorsInhibitorinhibitorinhibit

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