1. GPCR/G Protein
  2. Prostaglandin Receptor

Bimatoprost (Synonyms: AGN 192024)

Cat. No.: HY-B0191 Purity: 96.97%
Data Sheet SDS Handling Instructions

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

For research use only. We do not sell to patients.
Bimatoprost Chemical Structure

Bimatoprost Chemical Structure

CAS No. : 155206-00-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO $165 In-stock
1 mg $50 In-stock
5 mg $180 In-stock
10 mg $280 In-stock
50 mg $800 In-stock
100 mg   Get quote  
200 mg   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Target: Prostaglandin Receptor Bimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure (IOP) by increasing the outflow of aqueous fluid from the eyes. In December 2008, the indication to lengthen eyelashes was approved by the U.S. Food and Drug Administration (FDA); the cosmetic formulation of bimatoprost is sold as Latisse. In 2008-2011, at least three case series suggested that bimatoprost has the ability to reduce adipose (fat) tissue. Bimatoprost activates prostamide alpha F2 receptors found in the hair follicle to stimulate its growth rate. Research led by Professor Randall and the University of Bradford found that it may also offer a treatment for scalp hair regrowth in trials conducted on samples taken from men undergoing hair transplants. According to Allergan's package labeling, users of its Latisse cosmetic product didn't develop darker irises in clinical studies; however, "patients should be advised about the potential for increased brown iris pigmentation which is likely to be permanent."

Clinical Trial
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References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 2.4063 mL 12.0317 mL 24.0633 mL
5 mM 0.4813 mL 2.4063 mL 4.8127 mL
10 mM 0.2406 mL 1.2032 mL 2.4063 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

415.57

Formula

C₂₅H₃₇NO₄

CAS No.

155206-00-1

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Bimatoprost
Cat. No.:
HY-B0191
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