Bimatoprost-d5
Based on 1 Customer Validation
Bimatoprost-d5 is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect.
For research use only. We do not sell to patients.
- Purity: 98.24%
- Formula: C25H32D5NO4
- Molecular Weight:420.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 155206-00-1
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Appearance Solid
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Molecular Weight 420.60
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Formula C25H32D5NO4
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Color White to off-white
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SMILES
O=C(NC([2H])([2H])C([2H])([2H])[2H])CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C[C@@H]1O
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Synonyms
AGN 192024 d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (237.76 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Park J, et al. Changes to upper eyelid orbital fat from use of topical bimatoprost, travoprost, and latanoprost. Jpn J Ophthalmol. 2011 Jan;55(1):22-7. [Content Brief]
[2]. Krauss AH, et al. Update on the mechanism of action of bimatoprost: a review and discussion of new evidence. Surv Ophthalmol. 2004 Mar;49 Suppl 1:S5-11. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3776 mL | 11.8878 mL | 23.7756 mL | 59.4389 mL |
| 5 mM | 0.4755 mL | 2.3776 mL | 4.7551 mL | 11.8878 mL | |
| 10 mM | 0.2378 mL | 1.1888 mL | 2.3776 mL | 5.9439 mL | |
| 15 mM | 0.1585 mL | 0.7925 mL | 1.5850 mL | 3.9626 mL | |
| 20 mM | 0.1189 mL | 0.5944 mL | 1.1888 mL | 2.9719 mL | |
| 25 mM | 0.0951 mL | 0.4755 mL | 0.9510 mL | 2.3776 mL | |
| 30 mM | 0.0793 mL | 0.3963 mL | 0.7925 mL | 1.9813 mL | |
| 40 mM | 0.0594 mL | 0.2972 mL | 0.5944 mL | 1.4860 mL | |
| 50 mM | 0.0476 mL | 0.2378 mL | 0.4755 mL | 1.1888 mL | |
| 60 mM | 0.0396 mL | 0.1981 mL | 0.3963 mL | 0.9906 mL | |
| 80 mM | 0.0297 mL | 0.1486 mL | 0.2972 mL | 0.7430 mL | |
| 100 mM | 0.0238 mL | 0.1189 mL | 0.2378 mL | 0.5944 mL |