Search Result
Results for "
photosensitizing
" in MedChemExpress (MCE) Product Catalog:
4
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-D1648
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Fluorescent Dye
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Others
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8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λabs=502 nm, λem=516 nm) (*abs: main absorption maxima) .
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- HY-157503
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Others
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Cancer
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Photosensitizer-3 is a photosensitizer that exhibits powerful selective killing effects on transfected HEK cells and affibody-targeted A431 cancer cells when exposed to near-infrared light excitation .
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- HY-146416
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Others
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Cancer
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Antitumor photosensitizer-2 (Compound 11) is a potent photosensitizer. Antitumor photosensitizer-2 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new agent candidates for photodynamic research .
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- HY-146414
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Others
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Cancer
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Antitumor photosensitizer-1 (Compound 8) is a potent photosensitizer. Antitumor photosensitizer-1 has outstanding photodynamic anti-tumor effects without obvious skin photo-toxicity, and can act as new agent candidates for photodynamic research .
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- HY-145265
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Bacterial
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Infection
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Antimicrobial photosensitizer-1 is a promising candidate as the antimicrobial photosensitizer for combating pathogenic microorganism infections. Antimicrobial photosensitizer-1 exhibits an impressive antimicrobial efficacy in S. aureus-infected mice wounds .
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- HY-156092
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BCRP
Apoptosis
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Cancer
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Antitumor photosensitizer-4 (compound 10b) is a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. Antitumor photosensitizer-4 is a photosensitizer (PS) consisting of a conjugate of dasatinib (HY-10181) and imatinib (HY-15463). Antitumor photosensitizer-4 induces apoptosis and ROS production and exhibits strong phototoxicity to HepG2 and B16-F10 cells .
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- HY-157943
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HAL
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Fluorescent Dye
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Cancer
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Hexyl 5-aminolevulinate (HAL) is a photosensitizer, and can increase the efficiency of PDT due to the high lipophilicity. Hexyl 5-aminolevulinate can be used for research of photodynamic therapy (PDT) .
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- HY-D1472
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Fluorescent Dye
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Others
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Azure A eosinate is a dye for hematological and histological applications. Azure A eosinate can be used as new photosensitizer prototypes to determine growth inhibition of Candida albicans .
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- HY-155070
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DNA/RNA Synthesis
Apoptosis
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Cancer
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SRE-II, an amide derivative, is an activatable photosensitizer for photodynamic cancer research with decreased fluorescence and photosensitizing capabilities. SRE-II can be further converted into the active photosensitizer SDU Red via carboxylesterase-catalyzed amide bond cleavage. SRE-II induces DNA damage and cell apoptosis in the presence of light. SRE-II can act as a promising theranostic agent for triple-negative breast cancer .
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- HY-117665
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TPCS2a
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Others
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Cancer
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Fimaporfin (TPCS2a) is an endosomal/lysosomal-localizing photosensitizer .
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- HY-P2213
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MMP
Apoptosis
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Cancer
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GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
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- HY-P2213A
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MMP
Apoptosis
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Cancer
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GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
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- HY-16477
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ME2906; Mono-L-aspartyl chlorin e6; NPe6
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Others
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Cancer
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Talaporfin (ME2906) sodium is a chlorin based photosensitizer. Talaporfin sodium can be used for the research of various cancers by using photodynamic therapy (PDT) .
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- HY-137475
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Reactive Oxygen Species
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Cancer
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Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT) .
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- HY-D1673
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Fluorescent Dye
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Cancer
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Tetrabromorhodamine 123 (TBR) bromide is a photosensitizer. Tetrabromorhodamine 123 bromide can be used for the research of photo dynamic therapy (PDT) and cancer .
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- HY-149778
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Fungal
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Infection
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Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC50 = 1 nM for T. rubrum) .
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- HY-U00128
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Parasite
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Infection
Inflammation/Immunology
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PPA-904 is a specific phenothiazine photosensitizer in photodynamic research (PDT) research, especially topical application for cutaneous leishmaniasis in vivo .
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- HY-137474
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Others
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Cancer
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Purpurin 18 methyl ester, a chlorophyll-a derivative, is a photosensitizer that can be used in photodynamic therapy (PDT). Purpurin 18 methyl ester has photodynamic activity to induce cancer cell death .
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- HY-D1452
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Fluorescent Dye
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Cancer
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BDP-4 is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .
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- HY-D1453
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Biochemical Assay Reagents
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Cancer
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Immune initiator-1 (Compound 1a) is an amino acid-modified near-infrared Aza-BODIPY photosensitizer, acts as an immune initiator for potent photodynamic research in melanoma .
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- HY-B0754
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Hematoporphyrin IX
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Apoptosis
Endogenous Metabolite
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Cancer
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Hematoporphyrin (Hematoporphyrin IX), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light .
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- HY-B0754A
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Hematoporphyrin IX dihydrochloride
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Apoptosis
Endogenous Metabolite
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Cancer
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Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride), a photosensitizer, is a substrate for affinity chromatography of heme-binding proteins. Hematoporphyrin dihydrochloride can induce apoptosis in U87 glioma cells and decrease tumor growth in vivo when exposed to red light .
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- HY-144314
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Estrogen Receptor/ERR
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Cancer
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PSDalpha is an ERα degrader conjugating photosensitizer (PS), triphenylamine benzothiadiazole (TB) and 17β-estradiol via an acetylene bond. PSDalpha shows excellent anti-proliferation performance on MCF-7 cells. The maximum absorption wavelength of PSDalpha in the visible region is located at 465 nm .
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- HY-126861
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Reactive Oxygen Species
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Others
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2'-Deoxy-5-formylcytidine is an effective internal triplet photosensitizer in DNA. 2'-Deoxy-5-formylcytidine could act as a new hot spot in DNA photodamage .
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- HY-N10611
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Reactive Oxygen Species
Apoptosis
Autophagy
Fungal
Fluorescent Dye
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Infection
Cancer
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Elsinochrome A is a perylene quinone photosensitizer, and can generate reactive oxygen species (ROS) to induce apoptosis and autophagy under light excitation. Elsinochrome A also shows antifungal activity against C. albicans biofilm through photodynamic antimicrobial chemotherapy (PACT). Elsinochrome A can be used for research of photodynamic therapy (PDT) (Ex: 460 nm) .
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- HY-157051
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Others
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Cancer
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[Ru(DIP)2TAP]Cl2, Ruthenium(II) polypyridyl compound, is a photosensitizer. [Ru(DIP)2TAP]Cl2 can be used for the research of photodynamic therapy (PDT) .
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- HY-137473
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Pyropheophorbide-a methyl ester
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Apoptosis
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Cancer
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Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth .
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- HY-16488
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m-THPC; KW2345
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Reactive Oxygen Species
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Cancer
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Temoporfin (m-THPC), a reduced porphyrin, is a potent second-generation photosensitizer. Temoporfin can be used in the research of photodynamic therapy (PDT) for head and neck cancers .
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- HY-150015
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DNA/RNA Synthesis
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Cancer
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4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent .
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- HY-151940
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Reactive Oxygen Species
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Cancer
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Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells .
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- HY-150970
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Pyroptosis
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Cancer
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ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm,λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway .
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- HY-D1293
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- HY-D1293A
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- HY-147521
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Necroptosis
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Cancer
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Antitumor photosensitizer-3 (Compound I) is a chlorin derivative. Antitumor photosensitizer-3 induces tumor cells apoptosis and necrosis under 650 nm laser irradiation. Antitumor photosensitizer-3 exhibits lower skin photo-toxicity than positive reference m-THPC in vivo .
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- HY-147690
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Others
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Cancer
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Photosensitizer-2 (compound 1) is a organic D-π-A sensitizer against phototoxicity. Photosensitizer-2 contains an acrylic acid moiety that exerts high levels of phototoxicity. Photosensitizer-2 shows antitumor activity against HeLa cells, with IC50 values of 20.9 ± 4.5 μM (dark) and 0.046 ± 0.012 μM (irradiation), respectively .
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- HY-163034
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Apoptosis
Reactive Oxygen Species
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Cancer
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Antitumor photosensitizer-5 (Ru2) is a photosensitizer which effectively target tumor mitochondria with an IC50 of 0.3 μM for phototoxicity to A549 cells. Under 460 nm light irradiation, antitumor photosensitizer-5 induces the generation of reactive oxygen species and NADH depletion, causes mitochondrial damage and activation of caspase-3, inducing apoptosis and suppressing cell migration. Antitumor photosensitizer-5 has the potential to prevent the growth of malignant tumors, therefore, shows the potential to be applied to photodynamic therapy .
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- HY-B1814
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Synkamin; Synkamin base
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Pyruvate Kinase
Bacterial
Fungal
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Infection
Cancer
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Vitamin K5 (Synkamin) is a photosensitizer and a antimicrobial agent. Vitamin K5 is a specific PKM2 inhibitor with IC50 values of 28, 191 and 120 μM for PKM2, PKM1 and PKL. Vitamin K5 induces apoptosis of colon 26 cells. Vitamin K5 can be used for the research of infection and cancer, and it also can be used as a preservative for pharmaceuticals, foods, and beverages .
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- HY-134990
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Apoptosis
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Cancer
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Hematoporphyrin monomethyl ether, second generation of porphyrin-related photosensitizer, is characterized by its single form, high yield of singlet oxygen, high selectivity, and low toxicity, which has been widely used in the diagnosis and research of various tumors, including lung cancer, bladder cancer, and nevus flammeus and brain glioma .
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- HY-W130236
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Cholinesterase (ChE)
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Cancer
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Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy) .
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- HY-128972
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- HY-128973
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- HY-111959
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- HY-13722
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HPPH
3 Publications Verification
Photochlor
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Reactive Oxygen Species
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Cancer
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HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent.
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- HY-145241
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Others
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Neurological Disease
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TBTDC is a highly efficient multifunctional organic photosensitizer with aggregation-induced emission for in vivo bioimaging and photodynamic research.
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- HY-131410
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Others
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Cancer
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Sinoporphyrin (sodium) (DVDMS-2) is a potential photosensitizer that inhibits tumor growth in vivo and in vitro and can be used in cancer research .
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- HY-D2189
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IRDye 700DX NHS ester
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Fluorescent Dye
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Others
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IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
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- HY-W035051
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Fluorescent Dye
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Infection
Cancer
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TSPP tetrasodium is a photosensitizer that has shown impressive effects in in vivo regression of cancer and microorganism infections (Ex: 413 nm, Em: 640 nm) .
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- HY-17644
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LUZ11; F2BMet
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Redaporfin (LUZ11) acts as a potent photosensitizer. Redaporfin causes direct antineoplastic effects as well as indirect immune-dependent destruction of malignant lesions .
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- HY-D0259
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Erythrosin extra bluish
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Fluorescent Dye
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Others
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Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
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- HY-157053
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Others
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Cancer
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[Ru(dppn)2phen](PF6)2 (compound 4) is a polypyridylruthenium compound used in photodynamic therapy (PDT). [Ru(dppn)2phen](PF6)2 is normally nontoxic under dark conditions and induces mitochondrial respiratory damage upon light exposure. [Ru(dppn)2phen](PF6)2 exhibits high levels of singlet oxygen quantum yield and phototoxicity against cancer cells .
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- HY-128419
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Others
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Others
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Biguanidinium-porphyrin is a mitochondria-targeting photosensitizer. Biguanidinium-porphyrin distributes within cell membranes with a large component in vesicles that correlated to some extent with the lysosomes and, upon longer exposures, in mitochondria and the cytosolic membrane .
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- HY-W127820
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Tetrakis(2-N-methylpyridyl)porphine chloride
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Biochemical Assay Reagents
Fluorescent Dye
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Others
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H2TMpyP-2 (tetrakis(2-N-methylpyridyl)porphine) chloride is an active photosensitizer with strong absorption properties in the visible to near-infrared region and excellent singlet oxygen quantum yield. Captisol-TMPyP complexes can be used in supramolecular nanosynthesis to increase singlet oxygen production, improve photostability and better photosensitization, and support photodynamic therapy activity. The Captisol:TMPyP complex also exhibited antibacterial activity against Escherichia coli and was cytotoxic against lung cancer A549 cells .
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- HY-N2575
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PKC
Bacterial
Parasite
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Infection
Cancer
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Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising photosensitizer for anticancer photodynamic therapy (PDT) .
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- HY-W424779
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Drug Metabolite
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Infection
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5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine . 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine .
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- HY-125665
-
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Apoptosis
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Cardiovascular Disease
Cancer
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Pheophorbide A is an intermediate product in the chlorophyll degradation pathway. Pheophorbide A can be used as a photosensitizer. Pheophorbide A is a lymphatic vascular activator. Pheophorbide A has antitumor activity. Pheophorbide A can be used for human lymphatic vascular insufficiencies research .
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- HY-N1453
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|
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Hypocrellin B, a pigment isolated from the fungi Hypocrella bambusae and Shiraia bambusicola, is an apoptosis inducer. Hypocrellin B can be used as a photosensitizer for photodynamic therapy of cancer. Hypocrellin B also has antimicrobial and antileishmanial activities .
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- HY-155003
-
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Fluorescent Dye
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Cancer
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TPEQM-DMA is a NIR-II photosensitizer. TPEQM-DMA accumulates in cancerous mitochondria, and inhibits cancer cell growth. TPEQM-DMA has potent type-I phototherapeutic efficacy to overcome the intrinsic pitfalls of PDT in combating hypoxic tumors .
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- HY-B1157
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Trisoralen; Trioxysalen; TMP
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DNA Alkylator/Crosslinker
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Inflammation/Immunology
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Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation .
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- HY-W127725
-
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Biochemical Assay Reagents
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Others
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Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.
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- HY-B0146
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Verteporfin
Maximum Cited Publications
142 Publications Verification
CL 318952
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YAP
Apoptosis
Autophagy
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Cancer
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Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .
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- HY-N6743
-
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PKC
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Cancer
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Cercosporin is produced by a plant pathogen, Pseudocercosporella capsellae. Cercosporin is a potent photosensitizer with a short activation wavelength, mostly suitable for superficial photodynamic therapy (PDT) treatments, especially when it is necessary to avoid perforations .
Cercosporin contains the perylenequinone structural features necessary to PKC activity with an IC50 of 0.6-1.3 μM .
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- HY-13594
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Ce6
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Bcl-2 Family
Caspase
PARP
Apoptosis
Fluorescent Dye
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Infection
Cancer
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Chlorin e6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
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- HY-132141
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5-Propargylamino-dUTP
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DNA/RNA Synthesis
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Others
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5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery . 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-147915
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Reactive Oxygen Species
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Cancer
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Benz-AP is a potent photosensitizer. Benz-AP produces singlet oxygen, with a negative correlation with hCES2 (Human carboxylesterase 2) activity. Benz-AP displays a higher photocytotoxicity potency in cancer cells under low hCES2 environments. Upon TPE (Two-photon excitation), Benz-AP produces ROS and kills cancer cells and tumor spheroids .
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- HY-W127805
-
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Biochemical Assay Reagents
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Others
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Pentacarboxylporphyrin I dihydrochloride is an organic compound belonging to the family of porphyrin derivatives. It is commonly used in biochemical research as a reference standard for the quantification of porphyrins and related compounds in biological samples. Pentacarboxylporphyrin I dihydrochloride has several applications in the diagnosis and monitoring of porphyrias, a group of inherited disorders characterized by abnormalities in heme metabolism. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.
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- HY-W127809
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Biochemical Assay Reagents
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Others
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Chlorin e4 is an organic compound belonging to the family of chlorins, which are macrocyclic compounds with a similar structure to porphyrins. It is commonly used to improve photodynamic therapy for cancer and other diseases. Chlorin e4 has multiple applications in medical research, including as a photosensitizer for localized tumor destruction. In addition, its antimicrobial properties and potential use in disinfection applications were investigated.
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- HY-161341
-
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Others
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Cancer
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β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity. β-Glucuronidase responsive conjugate 1 inhibits T-24 cell viability and growth with an IC50 of 0.2 μM. β-Glucuronidase responsive conjugate 1 can used to study bladder cancers .
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- HY-W011240
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Methforylthiazidine; Rontyl
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Others
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Metabolic Disease
Endocrinology
|
Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas .
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- HY-D1719A
-
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Fluorescent Dye
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Cancer
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Cypate is a near-infrared fluorescent dye that belongs to the family of photosensitizers. Cypate has high photostability and optical properties, and is often used in near-infrared optical imaging, as well as optical imaging, tumor marking, and drug delivery. In addition, Cypate is also used as a molecular probe and combined with targeting molecules (such as CBT or small interfering RNA) to achieve efficient detection and imaging of specific cells or tissues .
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- HY-B0146R
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CL 318952 (Standard)
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YAP
Apoptosis
Autophagy
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Cancer
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Verteporfin (Standard) is the analytical standard of Verteporfin. This product is intended for research and analytical applications. Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis . Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation .
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- HY-W008566
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Norharman; β-Carboline
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Monoamine Oxidase
Endogenous Metabolite
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Infection
Neurological Disease
Cancer
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Norharmane (Norharman), a β-carboline alkaloid, is a potent and reversible monoamine oxidase inhibitor, with IC50 values of 6.5 and 4.7 μM for MAO-A and MAO-B, respectively. Norharmane causes antidepressant responses. Norharmane is also a prospective anti-cancer photosensitizer. Norharmane alters polar auxin transport (PAT) by inhibiting PIN2, PIN3 and PIN7 transport proteins, thus causing a significant inhibitory effect on the growth of Arabidopsis thaliana seedlings .
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- HY-W051271
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Titanium dioxide
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Biochemical Assay Reagents
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Others
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Titanium(IV) oxide is a photosensitizer. Titanium(IV) oxide can be used as an excipient, such as glidant, coating agent, opacifier, coloring agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs .
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- HY-149801A
-
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Bacterial
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Infection
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Antibacterial agent 140 chloride is a promising antibacterial agent. Antibacterial agent 140 chloride is also the first Ru-based AIEgen photosensitizer for simultaneous dual applications of Gram-positive bacteria (G+) detection and treatment. Antibacterial agent 140 chloride uniquely selective discriminates and efficient exterminates Gram-positive bacteria (G+) from other bacteria due to its interaction with lipoteichoic acids (LTA). Antibacterial agent 140 chloride also possessed robust antibacterial activity for G+ under light irradiation .
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- HY-D1658
-
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Fluorescent Dye
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Others
|
BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups .
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- HY-151486
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GLUT
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Cancer
|
GLUT1-IN-1 is a glucose transporter 1 (GLUT1) inhibitor and has a GLUT1-specific inactivation ability. GLUT1-IN-1 exhibits concentration-dependent cytotoxicity for HeLa, A549 and HepG2 cells with IC50 values of 5.49 μM, 11.14 μM, and 8.73 μM, respectively. GLUT1-IN-1 can be used for the research of photodynamic therapy (PDT) and severals cancer .
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Cat. No. |
Product Name |
Type |
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- HY-D0259
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Erythrosin extra bluish
|
Fluorescent Dyes/Probes
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Erythrosine B is an artificial dye widely used in the food and textile industries. Erythrosine B is also a novel photosensitizer which has been used to develop animal models.
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- HY-D1648
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Fluorescent Dyes/Probes
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8-(2,4,6-Trimethylphenyl)-BODIPY is a highly fluorescent dye, can be used as photosensitizer or synthesize other BODIPY-based photosensitizer (λabs=502 nm, λem=516 nm) (*abs: main absorption maxima) .
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- HY-D1472
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Dyes
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Azure A eosinate is a dye for hematological and histological applications. Azure A eosinate can be used as new photosensitizer prototypes to determine growth inhibition of Candida albicans .
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- HY-D2189
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IRDye 700DX NHS ester
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Dyes
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IRDye 700DX (IRDye 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye that acts as a highly flexible photosensitizer .
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- HY-162129
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Fluorescent Dyes/Probes
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Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC50 value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics .
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- HY-W127725
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Dyes
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Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.
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- HY-D1658
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Fluorescent Dyes/Probes
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BDP 581/591 amine hydrochloride is a BODIPY dye linker. BDP 581/591 is a universal, photostable fluorophore. The addition of the amine group allows for the compound to react with carboxylic acids, activated NHS esters and other carbonyl groups .
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Cat. No. |
Product Name |
Type |
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- HY-W035051
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Biochemical Assay Reagents
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TSPP tetrasodium is a photosensitizer that has shown impressive effects in in vivo regression of cancer and microorganism infections (Ex: 413 nm, Em: 640 nm) .
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- HY-132141
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5-Propargylamino-dUTP
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Gene Sequencing and Synthesis
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5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery . 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-W127805
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Biochemical Assay Reagents
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Pentacarboxylporphyrin I dihydrochloride is an organic compound belonging to the family of porphyrin derivatives. It is commonly used in biochemical research as a reference standard for the quantification of porphyrins and related compounds in biological samples. Pentacarboxylporphyrin I dihydrochloride has several applications in the diagnosis and monitoring of porphyrias, a group of inherited disorders characterized by abnormalities in heme metabolism. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.
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- HY-W127809
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Biochemical Assay Reagents
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Chlorin e4 is an organic compound belonging to the family of chlorins, which are macrocyclic compounds with a similar structure to porphyrins. It is commonly used to improve photodynamic therapy for cancer and other diseases. Chlorin e4 has multiple applications in medical research, including as a photosensitizer for localized tumor destruction. In addition, its antimicrobial properties and potential use in disinfection applications were investigated.
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P2213A
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MMP
Apoptosis
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Cancer
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GPLGIAGQ TFA, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ TFA can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
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- HY-P2213
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MMP
Apoptosis
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Cancer
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GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting. GPLGIAGQ can be used to synthesis unique MMP2-targeted photosensitizer in photodynamic therapy (PDT) .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
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Classification |
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- HY-162129
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Azide
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Antitumor agent-131 (Compound 2-p) is an ER fluorescent probe with an IC50 value of 23 nM for HepG2 tumor cells. Antitumor agent-131 can be used as a photosensitizer for the study of cancer photodynamics .
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