Antifungal agent 87
Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC50 = 1 nM for T. rubrum).
For research use only. We do not sell to patients.
- CAS No.: 692730-21-5
- Formula: C14H14O4
- Molecular Weight:246.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
PDT-IC50 = 1 nM for T. rubrum
In Vitro
Antifungal agent 87(10) penetrates to a depth of approximately 50-70 μm in the cattle’s hoof keratin membranes, which has significant keratinophilic features[1].
Antifungal agent 87(10) produces local antifungal effects by irradiating light at keratinpenetrating wavelength (~500 nm)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 692730-21-5
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Molecular Weight 246.26
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Formula C14H14O4
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SMILES
O=C1C(CCCC)=CC(C2=C1C(O)=CC=C2O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)