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Temoporfin (Synonyms: m-THPC; KW2345)

Cat. No.: HY-16488 Purity: 95.28%
Handling Instructions

Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck.

For research use only. We do not sell to patients.

Temoporfin Chemical Structure

Temoporfin Chemical Structure

CAS No. : 122341-38-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 198 In-stock
Estimated Time of Arrival: December 31
5 mg USD 132 In-stock
Estimated Time of Arrival: December 31
10 mg USD 228 In-stock
Estimated Time of Arrival: December 31
25 mg USD 468 In-stock
Estimated Time of Arrival: December 31
50 mg USD 828 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products

Publications Citing Use of MCE Temoporfin

    Temoporfin purchased from MCE. Usage Cited in: Theranostics. 2018 Feb 4;8(5):1435-1448.

    In vivo fluorescence images of glioma-bearing mice intravenously receiving different mTHPC-containing formulations.
    • Biological Activity

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    Description

    Temoporfin(KW 2345) used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. Target: Others Temoporfin used in photodynamic therapy for the treatment of squamous cell carcinoma of the head and neck. Patients can remain photosensitive for several weeks after treatment.

    Clinical Trial
    Molecular Weight

    680.75

    Formula

    C₄₄H₃₂N₄O₄

    CAS No.

    122341-38-2

    SMILES

    OC1=CC=CC(/C2=C3CCC(/C(C4=CC(O)=CC=C4)=C5C=C/C(N/5)=C(C6=CC(O)=CC=C6)/C(C=C/7)=NC7=C(C8=CC(O)=CC=C8)/C9=CC=C2N9)=N\3)=C1

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 30 mg/mL (44.07 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 1.4690 mL 7.3448 mL 14.6897 mL
    5 mM 0.2938 mL 1.4690 mL 2.9379 mL
    10 mM 0.1469 mL 0.7345 mL 1.4690 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 1 mg/mL (1.47 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 1 mg/mL (1.47 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References
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    Keywords:

    Temoporfinm-THPCKW2345KW 2345KW-2345OthersInhibitorinhibitorinhibit

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    Product name:
    Temoporfin
    Cat. No.:
    HY-16488
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