Temoporfin (Foscan®, 5,10,15,20-tetra(m-hydroxyphenyl)chlorin)--a second-generation photosensitizer

  • Photochem Photobiol. 2011 Nov-Dec;87(6):1240-96. doi: 10.1111/j.1751-1097.2011.00986.x.
Mathias O Senge  1 ,  Johan C Brandt
Affiliations
  • 1. Medicinal Chemistry, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland. [email protected]
PMID: 21848905 DOI: 10.1111/j.1751-1097.2011.00986.x
Abstract

This review traces the development and study of the second-generation Photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin through to its acceptance and clinical use in modern photodynamic (Cancer) therapy. The literature has been covered up to early 2011.

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